Related references
Note: Only part of the references are listed.HIF-1: upstream and downstream of cancer metabolism
Gregg L. Semenza
CURRENT OPINION IN GENETICS & DEVELOPMENT (2010)
Lactacidosis modulates glutathione metabolism and oxidative glutamate toxicity
Jan Lawerenz et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Warburg effect in chemosensitivity: Targeting lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol
Ming Zhou et al.
MOLECULAR CANCER (2010)
Spatial correlation between brain aerobic glycolysis and amyloid-β (Aβ) deposition
Andrei G. Vlassenko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Regional aerobic glycolysis in the human brain
S. Neil Vaishnavi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
Anne Le et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Metabolic Modulation of Glioblastoma with Dichloroacetate
E. D. Michelakis et al.
SCIENCE TRANSLATIONAL MEDICINE (2010)
Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease
Magali Dumont et al.
FASEB JOURNAL (2009)
Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer
E. D. Michelakis et al.
BRITISH JOURNAL OF CANCER (2008)
Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells
Thomas McFate et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Alzheimer's disease is associated with reduced expression of energy in posterior cingulate metabolism genes neurons
Winnie S. Liang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Increase in expression levels and resistance to sulfhydryl oxidation of peroxiredoxin isoforms in amyloid β-resistant nerve cells
Robert C. Cumming et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
HIF-1 mediates the Warburg effect in clear cell renal carcinoma
Gregg L. Semenza
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2007)
Hypoxia-inducible factor 1α (HIF-1α)-mediated hypoxia increases BACE1 expression and β-amyloid generation
Xian Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Selective defect of in vivo glycolysis in early Huntington's disease striatum
William J. Powers et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Gene expression profiles of metabolic enzyme transcripts in Alzheimer's disease
Wendy M. Brooks et al.
BRAIN RESEARCH (2007)
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
Sebastien Bonnet et al.
CANCER CELL (2007)
Roles of amyloid beta-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment
D. Allan Butterfield et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
Transcriptional regulation of APH-1A and increased γ-secretase cleavage of APP and Notch by HIF-1 and hypoxia
Ruishan Wang et al.
FASEB JOURNAL (2006)
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
I Papandreou et al.
CELL METABOLISM (2006)
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
JW Kim et al.
CELL METABOLISM (2006)
Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
Valeria R. Fantin et al.
CANCER CELL (2006)
Glucose metabolism and Alzheimer's disease
D Schubert
AGEING RESEARCH REVIEWS (2005)
Pyruvate dehydrogenase and pyruvate dehydrogenase kinase expression in non small cell lung cancer and tumor-associated stromal
MI Koukourakis et al.
NEOPLASIA (2005)
Pain: Moving from symptom control toward mechanism-specific pharmacologic management
CJ Woolf
ANNALS OF INTERNAL MEDICINE (2004)
Why do cancers have high aerobic glycolysis?
RA Gatenby et al.
NATURE REVIEWS CANCER (2004)
Protein disulfide bond formation in the cytoplasm during oxidative stress
RC Cumming et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The regulation of glucose metabolism by HIF-1 mediates a neuroprotective response to amyloid beta peptide
T Soucek et al.
NEURON (2003)
Dichloroacetate effects on glucose and lactate oxidation by neurons and astroglia in vitro and on glucose utilization by brain in vivo
Y Itoh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Specificity of resistance to oxidative stress
R Dargusch et al.
JOURNAL OF NEUROCHEMISTRY (2002)
beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities
CS Casley et al.
JOURNAL OF NEUROCHEMISTRY (2002)