Related references
Note: Only part of the references are listed.Helicobacter pylori HtrA is a new secreted virulence factor that cleaves E-cadherin to disrupt intercellular adhesion
Benjamin Hoy et al.
EMBO REPORTS (2010)
A Medicinal Chemist's Guide to Molecular Interactions (vol 53, pg 5061, 2010)
Caterina Bissantz et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Automatic identification and representation of protein binding sites for molecular docking
Jim Ruppert et al.
PROTEIN SCIENCE (2010)
Structural basis of substrate specificity in the serine proteases
John J. Perona et al.
PROTEIN SCIENCE (2010)
Troubleshooting computational methods in drug discovery
Sandhya Kortagere et al.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2010)
G Protein-Coupled Receptors: Target-Based In Silico Screening
Hanoch Senderowitz et al.
CURRENT PHARMACEUTICAL DESIGN (2009)
Form follows function: Shape analysis of protein cavities for receptor-based drug design
Martin Weisel et al.
PROTEOMICS (2009)
Combining docking with pharmacophore filtering for improved virtual screening
Megan L. Peach et al.
JOURNAL OF CHEMINFORMATICS (2009)
The cell-cell adhesion molecule E-cadherin
F. van Roy et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Hot-spots-guided receptor-based pharmacophores (HS-Pharm): A knowledge-based approach to identify ligand-anchoring atoms in protein cavities and prioritize structure-based pharmacophores
Caterina Barillari et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2008)
Targets Looking for Drugs: A Multistep Computational Protocol for the Development of Structure-Based Pharmacophores and Their Applications for Hit Discovery
Cristina Tintori et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2008)
Structure-activity landscape index: Identifying and quantifying activity cliffs
Rajarshi Guha et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2008)
How to do an evaluation: pitfalls and traps
Paul C. D. Hawkins et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2008)
Essential factors for successful virtual screening
Markus H. J. Seifert et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2008)
Structural basis for the regulated protease and chaperone function of DegP
Tobias Krojer et al.
NATURE (2008)
Prediction of Extracellular Proteases of the Human Pathogen Helicobacter pylori Reveals Proteolytic Activity of the Hp1018/19 Protein HtrA
Martin Loewer et al.
PLOS ONE (2008)
New concepts of resistance in the treatment of Helicobacter pylori infections
David Y. Graham et al.
NATURE CLINICAL PRACTICE GASTROENTEROLOGY & HEPATOLOGY (2008)
Scaffold hopping by Fuzzy pharmacophores and its application to RNA targets
Yusuf Tanrikulu et al.
CHEMBIOCHEM (2007)
Soluble cadherins as cancer biomarkers
Olivier De Wever et al.
CLINICAL & EXPERIMENTAL METASTASIS (2007)
CagA-independent disruption of adherence junction complexes involves E-cadherin shedding and implies multiple steps in Helicobacter pylori pathogenicity
Christiane Weydig et al.
EXPERIMENTAL CELL RESEARCH (2007)
PocketPicker: analysis of ligand binding-sites with shape descriptors
Martin Weisel et al.
CHEMISTRY CENTRAL JOURNAL (2007)
Evaluating virtual screening methods: Good and bad metrics for the early recognition problem
Jean-Francois Truchon et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2007)
In silico pharmacology for drug discovery: methods for virtual ligand screening and profiling
S. Ekins et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
A pseudo-ligand approach to virtual screening
Andreas Schueller et al.
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2006)
E-cadherin in gastric cancer
Annie On On Chan
WORLD JOURNAL OF GASTROENTEROLOGY (2006)
An introduction to ROC analysis
Tom Fawcett
PATTERN RECOGNITION LETTERS (2006)
Screening drug-like compounds by docking to homology models: A systematic study
V Kairys et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2006)
LigandScout: 3-d pharmacophores derived from protein-bound Ligands and their use as virtual screening filters
G Wolber et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2005)
High-throughput modeling of human G-protein coupled receptors: Amino acid sequence alignment, three-dimensional model building, and receptor library screening
C Bissantz et al.
JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES (2004)
Helicobacter pylori virulence factors -: one part of a big picture
M Höcker et al.
LANCET (2003)
Collection of bioactive reference compounds for focused library design
P Schneider et al.
QSAR & COMBINATORIAL SCIENCE (2003)
SWISS-MODEL: an automated protein homology-modeling server
T Schwede et al.
NUCLEIC ACIDS RESEARCH (2003)
The Chemistry Development Kit (CDK): An open-source Java library for chemo- and bioinformatics
C Steinbeck et al.
JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES (2003)
The Protein Data Bank
HM Berman et al.
NUCLEIC ACIDS RESEARCH (2000)