Journal
PLOS ONE
Volume 6, Issue 3, Pages -Publisher
PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pone.0017530
Keywords
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Categories
Funding
- NIH [R21 EB007707]
- W.H. Coulter Foundation
- Integration of Medicine and Innovative Technology (CIMIT) under U.S. Army Medical Research Acquisition Activity Cooperative Agreement
- U.S. Army Medical Research & Materiel Command (USAMRMC)
- Telemedicine & Advanced Technology Research Center (TATRC), at Fort Detrick, MD
- [RO1 A1081534]
- [R21 AI087107]
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Blood banking has a broad public health impact influencing millions of lives daily. It could potentially benefit from emerging biopreservation technologies. However, although vitrification has shown advantages over traditional cryopreservation techniques, it has not been incorporated into transfusion medicine mainly due to throughput challenges. Here, we present a scalable method that can vitrify red blood cells in microdroplets. This approach enables the vitrification of large volumes of blood in a short amount of time, and makes it a viable and scalable biotechnology tool for blood cryopreservation.
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