Related references
Note: Only part of the references are listed.NMR evidence for differential phosphorylation-dependent interactions in WT and ΔF508 CFTR
Voula Kanelis et al.
EMBO JOURNAL (2010)
Structure and Dynamics of NBD1 from CFTR Characterized Using Crystallography and Hydrogen/Deuterium Exchange Mass Spectrometry
H. A. Lewis et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant
Shane Atwell et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2010)
Molecular models of the open and closed states of the whole human CFTR protein
Jean-Paul Mornon et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2009)
Cooperative Assembly and Misfolding of CFTR Domains In Vivo
Kai Du et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Chaperone displacement from mutant cystic fibrosis transmembrane conductance regulator restores its function in human airway epithelia
Fei Sun et al.
FASEB JOURNAL (2008)
Processing mutations disrupt interactions between the nucleotide binding and transmembrane domains of P-glycoprotein and the cystic fibrosis transmembrane conductance regulator (CFTR)
Tip W. Loo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Adeno-associated virus-targeted disruption of the CFTR gene in cloned ferrets
Xingshen Sun et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function
Adrian W. R. Serohijos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs
Christopher S. Rogers et al.
SCIENCE (2008)
Building an understanding of cystic fibrosis on the foundation of ABC transporter structures
Juan L. Mendoza et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2007)
Domain interdependence in the biosynthetic assembly of CFTR
Liying Cui et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Revertant mutants G550E and 4RK rescue cystic fibrosis mutants in the first nucleotide-binding domain of CFTR by different mechanisms
Monica Roxo-Rosa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis
Xiaodong Wang et al.
CELL (2006)
Structure of a bacterial multidrug ABC transporter
Roger J. P. Dawson et al.
NATURE (2006)
Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator
J. Michael Younger et al.
CELL (2006)
Folding of CFTR is predominantly cotranslational
B Kleizen et al.
MOLECULAR CELL (2005)
CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains
P Vergani et al.
NATURE (2005)
Impact of the ΔF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure
HA Lewis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Side chain and backbone contributions of Phe508 to CFTR folding
PH Thibodeau et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
The F508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR
K Du et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator
HA Lewis et al.
EMBO JOURNAL (2004)
A foldable CFTRΔF508 biogenic intermediate accumulates upon inhibition of the Hsc70-CHIP E3 ubiquitin ligase
JM Younger et al.
JOURNAL OF CELL BIOLOGY (2004)
Organic solutes rescue the functional defect in ΔF508 cystic fibrosis transmembrane conductance regulator
XM Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mutations in the nucleotide binding domain 1 signature motif region rescue processing and functional defects of cystic fibrosis transmembrane conductance regulator ΔF508
ACV deCarvalho et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation
GC Meacham et al.
NATURE CELL BIOLOGY (2001)
Share Paper
