4.6 Article

Inhibiting α-Synuclein Oligomerization by Stable Cell-Penetrating β-Synuclein Fragments Recovers Phenotype of Parkinson's Disease Model Flies

Related references

Note: Only part of the references are listed.
Review Neurosciences

α-Synuclein and neuronal cell death

Mark R. Cookson

MOLECULAR NEURODEGENERATION (2009)

Article Biochemistry & Molecular Biology

Assembly-dependent endocytosis and clearance of extracellular alpha-synuclein

He-Jin Lee et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2008)

Review Biochemistry & Molecular Biology

Parkinson's disease

Bobby Thomas et al.

HUMAN MOLECULAR GENETICS (2007)

Article Biochemistry & Molecular Biology

Structural characterization of the intrinsically unfolded protein β-synuclein, a natural negative regulator of α-synuclein aggregation

Carlos W. Bertoncini et al.

JOURNAL OF MOLECULAR BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Dynamics of α-synuclein aggregation and inhibition of pore-like oligomer development by β-synuclein

Igor F. Tsigelny et al.

FEBS JOURNAL (2007)

Article Biochemistry & Molecular Biology

Relationships between the sequence of α-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicity

Michael J. Volles et al.

JOURNAL OF MOLECULAR BIOLOGY (2007)

Review Multidisciplinary Sciences

A century-old debate on protein aggregation and neurodegeneration enters the clinic

Peter T. Lansbury et al.

NATURE (2006)

Article Biochemistry & Molecular Biology

Prediction of aggregation-prone and aggregation-susceptible regions in proteins associated with neurodegenerative diseases

AP Pawar et al.

JOURNAL OF MOLECULAR BIOLOGY (2005)

Article Neurosciences

Intravesicular localization and exocytosis of α-synuclein and its aggregates

HJ Lee et al.

JOURNAL OF NEUROSCIENCE (2005)

Article Multidisciplinary Sciences

Partial D-amino acid substitution:: Improved enzymatic stability and preserved Ab recognition of a MUC2 epitope peptide

R Tugyi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

beta-synuclein-derived peptides with neuroprotective activity - An alternative treatment of neurodegenerative disorders?

M Windisch et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2004)

Review Multidisciplinary Sciences

Folding proteins in fatal ways

DJ Selkoe

NATURE (2003)

Article Biochemistry & Molecular Biology

The N-terminal repeat domain of α-synuclein inhibits β-sheet and amyloid fibril formation

JC Kessler et al.

BIOCHEMISTRY (2003)

Article Multidisciplinary Sciences

Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases

F Chiti et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Review Neurosciences

Pathogenesis of Parkinson's disease:: Dopamine, vesicles and α-synuclein

J Lotharius et al.

NATURE REVIEWS NEUROSCIENCE (2002)

Article Biochemistry & Molecular Biology

α-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils

HA Lashuel et al.

JOURNAL OF MOLECULAR BIOLOGY (2002)

Review Biotechnology & Applied Microbiology

Therapeutic strategies for human amyloid diseases

JC Sacchettini et al.

NATURE REVIEWS DRUG DISCOVERY (2002)

Article Biochemistry & Molecular Biology

A possible role for pi-stacking in the self-assembly of amyloid fibrils

E Gazit

FASEB JOURNAL (2002)

Review Neurosciences

Targeting small Aβ oligomers:: the solution to an Alzheimer's disease conundrum?

WL Klein et al.

TRENDS IN NEUROSCIENCES (2001)

Review Biochemistry & Molecular Biology

Review: History of the amyloid fibril

JD Sipe et al.

JOURNAL OF STRUCTURAL BIOLOGY (2000)

Article Multidisciplinary Sciences

Fiber diffraction of synthetic α-synuclein filaments shows amyloid-like cross-β conformation

LC Serpell et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

Article Multidisciplinary Sciences

A Drosophila model of Parkinson's disease

MB Feany et al.

NATURE (2000)

Article Multidisciplinary Sciences

Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease:: Implications for pathogenesis and therapy

KA Conway et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)