Related references
Note: Only part of the references are listed.SIRT3 interacts with the daf-16 homolog FOXO3a in the Mitochondria, as well as increases FOXO3a Dependent Gene expression
Kristi Muldoon Jacobs et al.
International Journal of Biological Sciences (2012)
Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Enhances Antiproliferative Activity of 5′-Deoxy-5-Fluorouridine in Cancer Cells through Induction of Uridine Phosphorylase
Xingxing Kong et al.
MOLECULAR PHARMACOLOGY (2009)
A New Splice Variant of the Mouse SIRT3 Gene Encodes the Mitochondrial Precursor Protein
Helen M. Cooper et al.
PLOS ONE (2009)
Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3
Lei Jin et al.
PROTEIN SCIENCE (2009)
SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70
Nagalingam R. Sundaresan et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
Bong-Hyun Ahn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Mammalian sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
David B. Lombard et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival
Hongying Yang et al.
CELL (2007)
Sirtuins: critical regulators at the crossroads between cancer and aging
L. R. Saunders et al.
ONCOGENE (2007)
Sirtuins in mammals: insights into their biological function
Shaday Michan et al.
BIOCHEMICAL JOURNAL (2007)
Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRα and γ
Catherine R. Dufour et al.
CELL METABOLISM (2007)
SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress
Michael B. Scher et al.
GENES & DEVELOPMENT (2007)
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α
Zachary Gerhart-Hines et al.
EMBO JOURNAL (2007)
SIRT1: Linking adaptive cellular responses to aging-associated changes in organismal physiology
Dimitrios Anastasiou et al.
PHYSIOLOGY (2006)
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
Julie St-Pierre et al.
CELL (2006)
Mutation of succinate dehydrogenase subunit C results in increased O2•-, oxidative stress, and genomic instability
Benjamin G. Slane et al.
CANCER RESEARCH (2006)
Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases
William C. Hallows et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
Bjoern Schwer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
PGC-1 coactivators: inducible regulators of energy metabolism in health and disease
BN Finck et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Estrogen-related receptor α is a repressor of phosphoenolpyruvate carboxykinase gene transcription
B Herzog et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Activation of AMP-activated protein kinase reduces hyperglycemia-Induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells
D Kukidome et al.
DIABETES (2006)
PGC-1α coactivates PDK4 gene expression via the orphan nuclear receptor ERRα:: a mechanism for transcriptional control of muscle glucose metabolism
AR Wende et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
PGC-1α regulates the mitochondrial antioxidant defense system in vascular endothelial cells
I Valle et al.
CARDIOVASCULAR RESEARCH (2005)
Metabolic control through the PGC-1 family of transcription coactivators
JD Lin et al.
CELL METABOLISM (2005)
SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes
T Shi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
PGC-1α deficiency causes multi-system energy metabolic derangements:: Muscle dysfunction, abnormal weight control and hepatic steatosis
TC Leone et al.
PLOS BIOLOGY (2005)
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
JT Rodgers et al.
NATURE (2005)
Mitochondria, oxidants, and aging
RS Balaban et al.
CELL (2005)
A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages
D Bellizzi et al.
GENOMICS (2005)
PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3
SH Koo et al.
NATURE MEDICINE (2004)
Errα and Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle
VK Mootha et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The estrogen-related receptor α (ERRα) functions in PPARγ coactivator 1α (PGC-1α)-induced mitochondrial biogenesis
SN Schreiber et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Primary hepatocyte culture in collagen gel mixture and collagen sandwich
Ying-Jie Wang et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2004)
Defects in adaptive energy metabolism with CNS-Linked hyperactivity in PGC-1α null mice
JD Lin et al.
CELL (2004)
Estrogen receptor-related receptors: orphan receptors desperately seeking a ligand
B Horard et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2003)
Specific gene inhibition by adenovirus-mediated expression of small interfering RNA
LJ Zhao et al.
GENE (2003)
PPARγ coactivator 1β/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity
Y Kamei et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly
G Rose et al.
EXPERIMENTAL GERONTOLOGY (2003)
Bioenergetic analysis of peroxisome proliferator-activated receptor γ coactivators 1α and 1β (PGC-1α and PGC-1β) in muscle cells
J St-Pierre et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Peroxisome-proliferator-activated receptor δ activates fat metabolism to prevent obesity
YX Wang et al.
CELL (2003)
Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha
JM Luo et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Peroxisome proliferator-activated receptor coactivator-1α (PGC-1α) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-α and -γ -: Identification of novel leucine-rich interaction motif within PGC-1α
JM Huss et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria
P Onyango et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
The human silent information regulator NO homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
B Schwer et al.
JOURNAL OF CELL BIOLOGY (2002)
To ERR in the estrogen pathway
V Giguère
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2002)
Superoxide activates mitochondrial uncoupling proteins
KS Echtay et al.
NATURE (2002)
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
S Herzig et al.
NATURE (2001)
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
JC Yoon et al.
NATURE (2001)
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production
D Arsenijevic et al.
NATURE GENETICS (2000)
Cloning and characterization of two mouse genes with homology to the yeast Sir2 gene
YH Yang et al.
GENOMICS (2000)