Journal
PLASMA PROCESSES AND POLYMERS
Volume 11, Issue 6, Pages 596-605Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ppap.201400001
Keywords
biocompatibility; cardiovascular implants; platelet activation; polymer surface; weakly ionized oxygen plasma
Funding
- Slovenian Research Agency [Z3-4261]
- Ministry of Higher Education, Science and Technology of the Republic of Slovenia [3211-10-000057]
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Improved hemocompatibility from the perspective of platelets adhesion and activation on polyethylene terephthalate surfaces has been addressed. The activation stage of platelets has been determined from their size and morphology using scanning electron microscopy (SEM). The activation of platelets on untreated polymer materials was very intensive. Polymer materials were treated with weakly ionized oxygen plasma in order to repel platelet adhesion. Already short treatment times (3s) showed significant reduction of the total number and of highly activated forms of adhered platelets. Possible mechanisms of different behaviour of blood platelets on plasma treated polymer were discussed in terms of surface adhesion and changes in morphology.
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