4.5 Article

Bisnortriterpenoids Possessing an 18-Nor-schiartane Skeleton from Schisandra propinqua var. propinqua

Journal

PLANTA MEDICA
Volume 76, Issue 14, Pages 1611-1615

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1241018

Keywords

Propindilactone; Schisandra propinqua var. propinqua; Schisandraceae; triterpenoid; 18-nor-schiartane; anti-HBV activity

Funding

  1. NSFC [30830115, 2008GA031]
  2. Major State Basic Research Development Program of China [2009CB522300, 2009CB940900]
  3. CAS [KZCX2-XB2-15]
  4. NSF of the Yunnan Province [2007BC004]

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Six C(28) triterpenoids with an 18-nor-schiartane framework were isolated from the aerial parts of Schisandra propinqua var. propinqua. The new compounds, propindilactones P-S (1-4), were structurally characterized by extensive spectroscopic methods. New compounds 2 and 3, together with known wuweizidilactones B and H (5-6), were evaluated for their anti-HBV activity.

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