Journal
PLANTA MEDICA
Volume 77, Issue 3, Pages 284-286Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1250239
Keywords
monoterpenoid indole alkaloid; Turpinia arguta; Staphyleaceae; DNA strand scission
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Funding
- Chinese Academy of Sciences [KSCX2-YW-R-218]
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Two new monoterpenoid indole alkaloid derivatives, turpiniside (1) and 11-methoxyjavaniside (2), along with the known alkaloids, vincosamide (3), (3R)-pumiloside (4), and paratunamide C (5), were isolated from the leaves of Turpinia arguta (Lind1.) Seem. Their structures were determined on the basis of spectroscopic data. Compounds 1 and 3-5 were found to effect relaxation of the supercoiled pBR322 plasmid DNA in the presence of Cu2+.
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