Journal
PLANTA MEDICA
Volume 75, Issue 3, Pages 249-255Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0028-1112202
Keywords
Morus wittiorum; Moraceae; Diels-AldeF-type adducts; flavonoid; antioxidant activities
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Funding
- National Natural Science Foundation of China [20432 030]
- Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine (Peking Union Medical College, Ministry of Education)
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Six new Diels-Alder-type adducts, wittiorumins A-F (1-6) along with the three known compounds chalcomoracin (7), mulberrofuran J (8), and mongolicin F (9), were isolated from the stem bark of Mortis wittiorum. Their structures including their absolute configurations were determined on the basis of spectroscopic analysis and chemical methods. Some of the isolated Compounds (1-4) were assayed for their antioxidant activities, among which compounds 1-3 were active as antioxidants, with inhibitory ratios of 73.0%, 82.0%, and 82.0%, respectively, at a concentration of 10(-5) M.
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