Journal
PLANTA MEDICA
Volume 76, Issue 5, Pages 464-466Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1186227
Keywords
antibacterial activity; Fomitopsis pinicola (Polyporaceae); lanostane triterpenoid; ergostane steroid; Bacillus cereus
Categories
Funding
- Direct For Mathematical & Physical Scien
- Division Of Chemistry [0923388] Funding Source: National Science Foundation
Ask authors/readers for more resources
Anti-Bacillus cereus bioassay-guided fractionation of a crude extract of the American mushroom, Fomitopsis pinicola, was performed using thin-layer chromatography, Sephadex LH-20 column chromatography, and preparative-scale HPLC. Five lanostane triterpenoids (1-5) and one ergostane steroid (6) were isolated and identified. Compound 1 is a new lanostane triterpenoid, and its structure was determined using 1D and 2D NMR experiments, HR-MS, and physical data. Each of the purified compounds (1-6) was tested for antibacterial activity against B. cereus using standard MIC assays. Compounds 1-6 had MIC values of 32, 16, 32, 32, 128, and 64 mu g/mL, respectively.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available