Journal
PLANTA MEDICA
Volume 75, Issue 11, Pages 1262-1265Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1185523
Keywords
Viburnum propinquum; Caprifoliaceae; chalcone glycosides; tetrahydrofuranoid lignan; antioxidative activity
Ask authors/readers for more resources
A new chalcone glycoside (2) and a new tetrahydrofuranoid lignan (3), along with 12 known compounds, were isolated from the stems and leaves of Viburnum propinquum Hemsl. The structures of all isolated compounds were deduced using spectroscopic and chemical methods. Antioxidative activities of most phenolic compounds were evaluated. Compounds 1 (3,4,2',4'-tetrahydroxy-trans-chalcone), 2 (3,4,2',4'-tetrahydroxy-trans-chalcone-2'-O-beta-D-glucoside), 12 (quercetin), 13 ((+)-dihydroquercetin), and 14 (eriodictyol) showed antioxidative capacities in the DPPH and hydroxyl free-radical assays, with IC50 values of 3.80-6.12 mu g/mL, and 9.24-11.87 mu g/mL, respectively. Compounds 1, 2, 12, 13, and 14 also exhibited inhibitory activities against lipid peroxidation in rat liver homogenate, with an inhibitory rate of 10.8-39.9% at 20 mu g/mL, 38.8-57.2% at 100 mu g/mL, and 44.2-72.4% at 200 mu g/mL, respectively.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available