Journal
PLANTA MEDICA
Volume 74, Issue 4, Pages 422-426Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2008-1034327
Keywords
Erythrino abyssinica; Leguminosae; chalcones; cytotoxic activity
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Four new chalcones 1-4, named abyssinones A-D, were isolated from the stem bark of the plant Erythrina abyssinica and their structures were elucidated on the basis of spectroscopic analyses. The compounds 1, 3, and 4 were found to exhibit moderate cytotoxic activity against the human colorectal cancer cell line (Caco2) with IC50 values of 13.3,15.1, and 11.1 mu M, respectively.
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