Journal
WORLD JOURNAL OF GASTROENTEROLOGY
Volume 21, Issue 25, Pages 7842-7850Publisher
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.v21.i25.7842
Keywords
Epidemiological study; Familial history; Hepatitis B surface antigen; Immunization; General population
Categories
Funding
- National S and T Major Project Foundation of China [2011ZX10004-902]
- Priority Academic Program Development of Jiangsu Higher Education Institutions, Jiangsu Province Health Development Project with Science and Education [ZX201109]
- Research and Innovation Project for College Graduates of Jiangsu Province of China [KYZZ_0265]
Ask authors/readers for more resources
AIM: To investigate hepatitis B virus (HBV) prevalence in the general population in China. METHODS: A total of 148931 individuals were investigated by multistage random sampling in Eastern China. Data were collected on demographics and hepatitis B vaccination history, and serum was tested for hepatitis B surface antigen (HBsAg) by ELISA. RESULTS: A total of 11469 participants (7.70%, 95% CI: 7.57%-7.84%) were positive for HBsAg. HBsAg prevalence was 0.77% among children < 5 years old but increased progressively from adolescents (1.40%-2.55%) to adults (5.69%-11.22%). A decrease in HBsAg prevalence was strongly associated with vaccination and familial history of HBV among both children and adult groups. Meanwhile, HBsAg risk in adults was associated with invasive testing and sharing needles. The HBV immunization rate among participants aged < 20 years was 93.30% (95% CI: 93.01%-93.58%). Significant difference in HBsAg prevalence appeared between vaccinated and unvaccinated participants (3.59% vs 10.22%). CONCLUSION: Although the national goal of HBsAg prevalence < 1% among children < 5 years old has been reached, immunization programs should be maintained to prevent resurgence.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available