Journal
PLANT MOLECULAR BIOLOGY REPORTER
Volume 32, Issue 2, Pages 558-565Publisher
SPRINGER
DOI: 10.1007/s11105-013-0673-1
Keywords
Epigenetics; Histonedemethylase; Methylation; Chromatin; JmjC
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Funding
- National Basic Research Program of China (973 program) [2012CB910900]
- National Natural Science Foundation of China [31200965, 31371308]
- Guangdong Natural Science Foundation [S2012040006474]
- Foundation of Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences
- National Science Council of Taiwan [101-2923-B-002-005-MY3, 101-2311-B-002-012-MY3, 102-2321-B-002-074-]
- National Taiwan University [101R892005]
- Academia Sinica [AS-1102-TP-B05]
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Histone methylation-transfer of methyl groups to lysines or arginines residues of histone tails-plays an important role in the regulation of gene expression in eukaryotic cells. Histone methylation levels are regulated by histone methyltransferases and histone demethylases. There are two types of histone lysine demethylases (KDMs) in eukaryotes: KDM1/LSD1-like and JmjC domain-containing demethylases. KDMs can regulate gene expression directly through histone modification or indirectly through DNA methylation and siRNA regeneration. Recent studies indicate that KDMs play important regulatory roles in plant growth and developmental processes such as flowering time control, hormone response and circadian regulation.
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