Journal
WORLD JOURNAL OF GASTROENTEROLOGY
Volume 21, Issue 46, Pages 12989-12995Publisher
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.v21.i46.12989
Keywords
Hepatocellular carcinoma; Hepatitis B virus; Hepatitis C virus; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis
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Nonalcoholic fatty liver disease (NAFLD) including nonalcoholic steatohepatitis (NASH) is globally increasing and has become a world-wide health problem. Chronic infection with hepatitis B virus or hepatitis C virus (HCV) is associated with hepatic steatosis. Viral hepatitis-associated hepatic steatosis is often caused by metabolic syndrome including obesity, type 2 diabetes mellitus and/or dyslipidemia. It has been reported that HCV genotype 3 exerts direct metabolic effects that lead to hepatic steatosis. In this review, the differences between NAFLD/NASH and viral hepatitis-associated steatosis are discussed.
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