Journal
PLANT CELL REPORTS
Volume 33, Issue 4, Pages 585-594Publisher
SPRINGER
DOI: 10.1007/s00299-013-1559-2
Keywords
Molecular pharming; Transgenic rice; endosperm; Plant-made pharmaceutical (PMP); Manufacturing of PMP
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Plants provide a promising expression platform for producing recombinant proteins with several advantages in terms of high expression level, lower production cost, scalability, and safety and environment-friendly. Molecular pharming has been recognized as an emerging industry with strategic importance that could play an important role in economic development and healthcare in China. Here, this review represents the significant advances using transgenic rice endosperm as bioreactor to produce various therapeutic recombinant proteins in transgenic rice endosperm and large-scale production of OsrHSA, and discusses the challenges to develop molecular pharming as an emerging industry with strategic importance in China.
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