Journal
PLANT BIOLOGY
Volume 10, Issue 2, Pages 231-236Publisher
WILEY
DOI: 10.1111/j.1438-8677.2007.00028.x
Keywords
14-3-3 proteins; gating K+ channel; KAT1; modulation; trafficking; voltage-dependence
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KAT1 is a cloned plant potassium channel belonging to the superfamily of Shaker-like Kv channels. Previous studies have shown that 14-3-3 proteins significantly increase KAT1 current by modifying the channel open probability. Employing a 14-3-3 scavenger construct to lower the long-term availability of endogenous 14-3-3 proteins, we found that 14-3-3 proteins not only control the voltage dependency of the channel but also the number of channels in the plasma membrane.
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