Journal
PLACENTA
Volume 35, Issue 5, Pages 331-333Publisher
W B SAUNDERS CO LTD
DOI: 10.1016/j.placenta.2014.03.008
Keywords
PPROM; PGRMC1; Expression; Fetal membrane cells
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PGRMC1 function is implicated in maintaining fetal membrane (FM) integrity. PGRMC1 was detectable primarily in the cytoplasm of FM cells and was actively regulated in FMs and relevant for PGRMC1-mediated progesterone action. By cell type, PGRMC1 expression was higher in amnion and chorion compared with decidua. By clinical phenotype, PGRMC1 expression was higher among preterm-no-labor and term-no-labor subjects compared to PPROM. PGRMC1 expression appears to be diminished in PPROM subjects. (C) 2014 Elsevier Ltd. All rights reserved.
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