4.7 Article

Acute Effect of High-dose Isoflavones from Pueraria lobata (Willd.) Ohwi on Lipid and Bone Metabolism in Ovariectomized Mice

Journal

PHYTOTHERAPY RESEARCH
Volume 26, Issue 12, Pages 1864-1871

Publisher

WILEY
DOI: 10.1002/ptr.4669

Keywords

puerarin; Pueraria lobata (Willd.) Ohwi; lipid metabolism; bone; ovariectomy

Funding

  1. Ministry of Health and Welfare, Republic of Korea [A050376]
  2. Ministry of Agriculture and Forestry [105054-03-2-HD110]
  3. Rural Development Administration, Republic of Korea [PJ008506]

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We investigated the acute metabolic effects of isoflavones from Pueraria lobata (Willd.) Ohwi (IPL) in ovariectomized (OVX) mice. After 4?weeks of IPL feeding at 500?mg/day/kg body weight (OVX500), plasma 17 beta-estradiol concentrations were significantly higher (+25%, p?

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