Journal
PHYTOTHERAPY RESEARCH
Volume 26, Issue 3, Pages 432-437Publisher
WILEY
DOI: 10.1002/ptr.3570
Keywords
quercetin; onion peel extract; adipokine; mesenteric fat; antiobesity
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Funding
- Korea Science and Engineering Foundation (KOSEF)
- Korea government (MOST) [R01-2008-000-20879-0]
- National Research Foundation of Korea [R01-2008-000-20879-0] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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We examined the effects of quercetin-rich onion peel extract supplementation on adipokine expressions from adipose tissues in a diet-induced obese animal model. Male Sprague-Dawley rats (n?=?24) were randomly assigned into control (n?=?8), high fat diet (HF, n?=?8) and high fat diet with onion peel extract (HFOE, n?=?8). After 8?weeks, serum biochemical parameters, weights of adipose tissues (epididymal, perirenal and mesenteric fats) and adipokine mRNA levels (adiponectin, IL (interleukin)-6 and visfatin) along with PPAR (peroxisome proliferator-activated receptor) ?2 from adipose tissues were measured. After the 8?week supplementation, mesenteric fat weights were lower in the HFOE group than the HF group (p?
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