Journal
PHYTOMEDICINE
Volume 15, Issue 8, Pages 635-638Publisher
ELSEVIER GMBH, URBAN & FISCHER VERLAG
DOI: 10.1016/j.phymed.2008.05.001
Keywords
antifungal drugs; Amphotericin B; synergism; Pelargonium graveolens
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In this work we highlight a possible synergistic anti-Candida effect between Melaleuca alternifolia, Origanum vulgare and Pelargonium graveolens essential oils and the antifungal compound Amphotericin B. The antifungal activity was assessed using the agar dilution method in eleven Candida strains. The results obtained indicate the occurrence of a synergistic interaction between the essential oils under study and Amphotericin B. P. graveolens essential oil appeared to be the most effective, inhibiting all the Candida species evaluated by this study. (c) 2008 Elsevier GmbH. All rights reserved.
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