4.5 Article

Anticancer effects of bioactive berry compounds

Journal

PHYTOCHEMISTRY REVIEWS
Volume 13, Issue 1, Pages 295-322

Publisher

SPRINGER
DOI: 10.1007/s11101-013-9319-z

Keywords

Anthocyanin; Anti-cancer; Anti-inflammatory; Anti-oxidant; Berry; Flavonoid

Categories

Funding

  1. Recherche Cancer et Sang'' foundation
  2. Recherches Scientifiques Luxembourg asbl
  3. Een Haerz fir Kriibskrank Kanner association
  4. Action Lions Vaincre le Cancer'' Luxembourg
  5. Fonds National de la Recherche Luxembourg
  6. Televie Luxembourg
  7. Foundation for Scientific Cooperation
  8. European Union [215009]
  9. National Research Foundation (NRF) by the MEST of Korea for Tumor Microenvironment Global Core Research Center (GCRC) grant [2012-0001184]
  10. Seoul National University Research grant
  11. Research Settlement Fund for the new faculty of SNU
  12. National Research Foundation of Korea [2011-0030001] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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In the present review, we describe chemical and chemopreventive properties as well as health benefits of both extracts and bioactive compounds from various types of berries including small soft-fleshed edible berries and from berry-like fruits such as strawberries, raspberries, blackberries, blueberries, mulberries, currants, gooseberries, elderberries, a double dagger ai berries, and pomegranates. In particular, we describe how berry-derided phytochemicals, including anthocyanidins, proanthocyanidins, flavonols, flavanols, stilbenoids, terpenoids, ellagitannins, and ellagic acid target oxidative and UV radiation stress-induced DNA damage, Helicobacter pilori infection, pro-inflammatory as well as the major cancer hallmarks.

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