4.3 Article

Four new bibenzyl derivatives from Dendrobium sinense

Journal

PHYTOCHEMISTRY LETTERS
Volume 9, Issue -, Pages 107-112

Publisher

ELSEVIER
DOI: 10.1016/j.phytol.2014.04.012

Keywords

Dendrobium sinense; Dendrosinen A; Dendrosinen B; Dendrosinen C; Dendrosinen D; Cytotoxicity

Funding

  1. Special Fund for Agro-Scientific Research in the Public Interest [201303117]
  2. National Support Science and Technology Subject [2013BAI11B04]
  3. Major Technology Project of Hainan Province [ZDZX2013023-1]
  4. National Natural Science Foundation of China [31160178]
  5. State Key Subject of Botany at Hainan University [071001]

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Four new bibenzyl derivatives, named dendrosinens A-D (1-4), together with twelve known phenolic compounds were isolated from the whole plant of Dendrobium sinense T. Tang et F. T. Wang, an endemic and endangered orchid in Hainan Island, PR China. Their structures were elucidated by 1D, 2D NMR (HMBC, HMQC, COSY and NOESY), and HREIMS analyses. Bioassay results demonstrated that compounds 5-8 showed cytotoxic activity. (C) 2014 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

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