Journal
PHYTOCHEMISTRY LETTERS
Volume 9, Issue -, Pages 184-187Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.phytol.2014.06.012
Keywords
Nicotiana tabacum; Phenolic amides; Tabamides A-C; Anti-tobacco mosaic virus activity
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Funding
- National Natural Science Foundation of China [31360081]
- Basic Research Foundation of Yunnan Tobacco Industry Co. Ltd. [2012JC01]
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Three new phenolic amides, tabamides A-C (1-3), together with three known phenolic amides (4-6), were isolated from the leaves of Nicotiana tabacum. Their structures were elucidated by spectroscopic methods, including extensive 1D- and 2D NMR techniques. Compounds 1-6 were also tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compound 1 exhibited high anti-TMV activity with inhibition rate of 38.6%, which is higher than that of positive control (ningnanmycin). The other compounds also showed potential anti-TMV activity with inhibition rates in the range of 15.3-26.5%, respectively. (C) 2014 Published by Elsevier B.V. on behalf of Phytochemical Society of Europe.
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