Journal
PHYTOCHEMISTRY LETTERS
Volume 7, Issue -, Pages 130-132Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.phytol.2013.11.001
Keywords
Miconia prasina; Melastomataceae; Flavanone; Flavanone glycoside; Cannabinoids receptors
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Funding
- National Institute of General Medical Sciences a component of the National Institutes of Health (NIH) [9P20GM104932]
- NIH National Center for Research Resources [C06RR14503]
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A glycosidic flavanone miconioside C (1) has been isolated from the methanolic extract of the stems of Miconia prasina, together with 7-O-beta-D-apiofuranosyl-(1 -> 6)-beta-D-glucopyranosylmatteucinol (2), miconioside B (3), matteucinol (4), farrerol (5) and desmethoxymatteucinol (6). Their structures were mainly established by extensive NMR studies (H-1 NMR, C-13 NMR, DEPT, H-1-H-1 COSY, HSQC, HMBC) and mass spectrometry. The compounds 1-3 were evaluated for in vitro binding assays using cannabinoid receptors (CB1 and CB2). (C) 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
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