Journal
PHYTOCHEMISTRY LETTERS
Volume 7, Issue -, Pages 120-123Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.phytol.2013.11.008
Keywords
Marine alga-derived fungus; Aspergillus wentii; Secondary metabolites; Antioxidant activity
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Funding
- programs of the Ministry of Science and Technology [2010CB833802, 2013AA092901]
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Eight secondary metabolites (1-8) including a new seco-anthraquinone (wentiquinone C, 1) and a new benzamide derivative (methyl 4-(3,4-dihydroxybenzamido) butanoate, 2), as well as three other derivatives (4, 7, and 8) that were isolated from natural source for the first time, were characterized from the EtOAc extracts of the marine alga-derived endophytic fungus Aspergillus wentii EN-48. The structures of the isolated compounds were elucidated on the basis of 1D and 2D NMR experiments. Each of the isolated compounds was evaluated for a, a-diphenyl-picrylhydrazyl (DPPH) radical scavenging activity, and some of them showed potent activities with IC50 values ranging from 5.2 to 99.4 mu g/mL, compared to the positive control, butylated hydroxytoluene (BHT), with an IC50 of 36.9 mu g/mL. (C) 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
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