Journal
PHYTOCHEMISTRY LETTERS
Volume 6, Issue 3, Pages 491-494Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.phytol.2013.06.007
Keywords
beta-Carbolines; Actinomycetes; Actinomadura; Bioactive secondary metabolite
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Funding
- Bioresources Research Network, National Center for Genetic Engineering and Biotechnology (BIOTEC)
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Four new beta-carbolines 1-4 and two new indoles 5-6 were isolated together with thirteen known compounds from actinomycete, Actinomadura BCC 24717. Structures of the new compounds, 1-6, were determined by NMR spectroscopic and MS spectrometric analyses. Compound 4 exhibited cytotoxicity to Vero cells and compound 6 showed antifungal activity with IC50 35.91 mu g/mL and 41.97 mu g/mL, respectively. (C) 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
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