4.7 Article

Secondary metabolites from a marine-derived fungus Aspergillus carneus Blochwitz

Journal

PHYTOCHEMISTRY
Volume 80, Issue -, Pages 123-131

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phytochem.2012.05.008

Keywords

Secondary metabolites; Marine-derived fungus; Aspergillus carneus; Trichocomaceae; Alkaloids; C-glycosides; Drimane sesquiterpenes

Funding

  1. Russian Foundation for Basic Research [RFBR N 09-04-00388, 11-04-00772-a]
  2. Program of the Presidium RAS Molecular and Cell Biology [FEBRAS N 12-III-B-05-73]
  3. President of the Russian Federation Program for Support of the Leading Scientific Schools [N 546.2012.4]

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Prenylated indole alkaloids, carneamides A-C (1-3), quinazolinone derivatives, carnequinazolines A-C (5-7), aryl C-glycosides, carnemycin A, B (8, 9) and a drimane sesquiterpenoid (10), together with known compounds (11-21) were isolated from the marine-derived fungus Aspergillus carneus (Trichocomaceae) KMM 4638. The antimicrobial and cytotoxic activities of the several alkaloids were examined. (C) 2012 Elsevier Ltd. All rights reserved.

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