Journal
PHYTOCHEMISTRY
Volume 72, Issue 9, Pages 935-941Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phytochem.2011.03.007
Keywords
Ginger; Zingerines; Alkaloids; Phase-trafficking; Natural products; Fractionation
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Funding
- National Institutes of Health (NIH) [1R21AT004182-01A2]
- University of Kansas Center for Research [2506014-910/099]
- LASPAU-Fulbright
- University of Costa Rica
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Three unprecedented purine-containing compounds, named [6]-, [8]-, and [10]-zingerines as they are 5-(6-amino-9H-purin-9-yl) analogs of [6]-, [8]-, and [10]-gingerols, respectively, were isolated from a methanolic extract of ginger rhizomes using a phase trafficking-based method that utilizes solid phase reagents allowing for fast and selective simultaneous separation of basic, acidic, and neutral components of natural products extracts. (C) 2011 Elsevier Ltd. All rights reserved.
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