4.7 Article

Antibacterial clerodane diterpenes from Goldenrod (Solidago virgaurea)

Journal

PHYTOCHEMISTRY
Volume 71, Issue 1, Pages 104-109

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phytochem.2009.09.032

Keywords

Goldenrod (or woundwort); Solidago virgaurea; Asteraceae; Clerodane; Diterpene; Solidagoic acid; Antibacterial; Staphylococcus aureus

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Nine clerodane diterpenes, solidagoic acids C-I (1-7), cleroda-3,13(14)-dien-16,15:18,19-diolide (8) and cleroda-3,13(14)-dien-15,16:18,19-diolide (9) were isolated and characterised from the ethanol-ethyl acetate (1:1) extract of Solidago virgaurea. The structures were determined by NMR spectroscopic analysis. Several displayed moderate antibacterial activity against Staphylococcus aureus. (C) 2009 Elsevier Ltd. All rights reserved.

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