Journal
PHYTOCHEMISTRY
Volume 71, Issue 13, Pages 1528-1533Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phytochem.2010.06.008
Keywords
Pine resin; Pinus massoniana; Pinaceae; Diterpenoid; Cytotoxicity; A431 cell; A549 cell
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Funding
- Commonweal Foundation of Jiangsu Province
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Five diterpenoids and 14 known diterpenoids were isolated from the petroleum ether extract of Pinus massoniana resin. Their structures were elucidated by spectroscopic data interpretation. The cytotoxic activities of these compounds were evaluated using the MTT method. The results showed that three of the less polar diterpenoids had strong cytotoxicity against A431 and A549 cancer cells, whereas those of high polarity had none. (C) 2010 Elsevier Ltd. All rights reserved.
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