Journal
PHYTOCHEMISTRY
Volume 70, Issue 6, Pages 807-815Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phytochem.2009.02.013
Keywords
Agave utahensis Engelm.; Agavaceae; Spirostanol saponins; Furostanol saponins; Cytotoxic activity; HL-60 cells
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Phytochemical investigation of the whole plants of Agave utahensis Engelm. (Agavaceae) has resulted in the isolation of 15 steroidal saponins (1-15), including five spirostanol saponins (1-5) and three furostanol saponins (11-13). Structures of compounds 1-5 and 11-13 were determined by spectroscopic analysis and the results of hydrolytic cleavage. The isolated compounds were evaluated for their cytotoxic activity against HL-60 human promyelocytic leukemia cells. (C) 2009 Elsevier Ltd. All rights reserved.
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