Journal
PHYTOCHEMISTRY
Volume 70, Issue 2, Pages 250-255Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phytochem.2008.12.007
Keywords
Sargassum fallax; Brown alga; Isolation; Structure elucidation; Meroditerpenoids; Chromenes; Natural products; Plastoquinones; Tetraprenyltoluquinols
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Funding
- Victorian Institute for Chemical Sciences (VICS)
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Chemical investigation of the southern Australian marine brown alga Sargassum fallax resulted in the isolation of three meroditerpenoids fallahydroquinone, fallaquinone and fallachromenoic acid together with the previously reported compounds sargaquinone [isolated and identified in a mixture with sargaquinoic acid), sargahydroquinoic acid, sargaquinoic acid and sargachromenol. As a result of this study the complete 2D NMR characterisation for sargaquinoic acid and sargahydroquinoic acid can now be reported for the first time. All structures were elucidated by detailed spectrometric analysis. Sargaquinoic acid and sargahydroquinoic acid displayed moderate antitumour activity. Crown Copyright (C) 2008 Published by Elsevier Ltd. All rights reserved.
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