4.5 Article

Relations between mucosal immunity and children's mental health The role of child sex

Journal

PHYSIOLOGY & BEHAVIOR
Volume 101, Issue 5, Pages 705-712

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.physbeh.2010.08.012

Keywords

Mucosal immunity; Salivary interleukin 6; Secretory immunoglobulin A; Child mental health; Internalizing symptoms; Externalizing symptoms; Sex differences

Funding

  1. AAES [ALA080-049]
  2. National Science Foundation [0623936]
  3. National Institutes of Health [R01-HD046795]
  4. Division Of Behavioral and Cognitive Sci
  5. Direct For Social, Behav & Economic Scie [0623936] Funding Source: National Science Foundation

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This study examines relations between children s salivary interleukin-6 ( IL-6) and secretory immunoglobulin A (SIgA) and mental health Child sex was considered as a moderator of relations Data were from 329 normally developing children (M age = 9 85 years SD = 98 years) 67% of children were European American and 33% were African American Saliva samples were obtained during the afternoon and assayed for SIgA and IL-6 Parents completed questionnaire measures of child internalizing and externalizing symptoms and children completed self-report measures of anxiety and depression Structural equation models were fit to the data and indicated that greater levels of salivary IL-6 and SIgA were associated with adjustment problems more strongly for girls than for boys (C) 2010 Elsevier Inc All rights reserved

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