Journal
PHYSIOLOGY
Volume 27, Issue 3, Pages 130-139Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00009.2012
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Funding
- National Heart, Lung, and Blood Institute [HL-77860]
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Protein kinase C (PKC) isoforms have emerged as important regulators of cardiac contraction, hypertrophy, and signaling pathways that influence ischemic/reperfusion injury. This review focuses on newer concepts regarding PKC isoform-specific activation mechanisms and actions that have implications for the development of PKC-targeted therapeutics.
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