Journal
PHYSIOLOGY
Volume 26, Issue 4, Pages 266-272Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00008.2011
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The intercalated cell of collecting ducts of the kidney is of two forms, the alpha form secretes acid, whereas the beta form secretes HCO3. Here, we review recent work that shows that the alpha form is derived from the beta form and that the pathway is mediated by an extracellular matrix protein called hensin/DMBT1.
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