4.5 Review

Social Regulation of Gene Expression in the Hypothalamic-Pituitary-Gonadal Axis

Journal

PHYSIOLOGY
Volume 26, Issue 6, Pages 412-423

Publisher

AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00032.2011

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Funding

  1. National Institute of Neurological Disorders and Stroke [F32NS-061431, NS-034950]
  2. National Science Foundation [IOS-0923588]
  3. Division Of Integrative Organismal Systems
  4. Direct For Biological Sciences [923588] Funding Source: National Science Foundation

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Reproduction is a critically important event in every animals' life and in all vertebrates is controlled by the brain via the hypothalamic-pituitary-gonadal (HPG) axis. In many species, this axis, and hence reproductive fitness, can be profoundly influenced by the social environment. Here, we review how the reception of information in a social context causes genomic changes at each level of the HPG axis.

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