Journal
PHYSIOLOGY
Volume 26, Issue 6, Pages 393-411Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00013.2011
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Funding
- BBSRC [BB/F015488/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/F015488/1] Funding Source: researchfish
- Biotechnology and Biological Sciences Research Council [BB/F015488/1] Funding Source: Medline
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Vertebrate locomotion must be adaptable in light of changing environmental, organismal, and developmental demands. Much of the underlying flexibility in the output of central pattern generating (CPG) networks of the spinal cord and brain stem is endowed by neuromodulation. This review provides a synthesis of current knowledge on the way that various neuromodulators modify the properties of and connections between CPG neurons to sculpt CPG network output during locomotion.
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