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What's New About Osmotic Regulation of Glycerophosphocholine

Journal

PHYSIOLOGY
Volume 24, Issue 4, Pages 245-249

Publisher

AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00009.2009

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Funding

  1. Intramural NIH HHS [ZIA HL001283-22] Funding Source: Medline

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Glycerophosphocholine is an abundant renal medullary organic osmolyte that protects renal medullary cells from the high interstitial concentrations of NaCl and urea to which they are normally exposed. We consider the metabolism of glycerophosphocholine, its osmotic regulation, and the recently discovered molecular identity of the enzymes that osmoregulate its abundance.

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