Journal
PHYSIOLOGY
Volume 24, Issue 2, Pages 127-139Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00042.2008
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Funding
- CIHR
- Christopher and Dana Reeve Foundation (CDRF)
- Institut de Recherche sur la Moelle et l'Encephale (IRME)
- Multidisciplinary Team
- Fonds de la Recherche en Sante du Quebec
- Groupe de Recherche sur le Systeme Nerveux Central
- Natural Sciences and Engineering Research Council of Canada
- CDRF
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After a complete spinal section, quadruped mammals (cats, rats, and mice) can generally regain hindlimb locomotion on a treadmill because the spinal cord below the lesion can express locomotion through a neural circuitry termed the central pattern generator (CPG). In this review, we propose that the spinal CPG also plays a crucial role in the locomotor recovery after incomplete spinal cord injury.
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