Journal
PHYSIOLOGY
Volume 23, Issue 4, Pages 187-193Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00002.2008
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Funding
- NHLBI NIH HHS [P50 HL055006-10, R37 HL048058, P01 HL084207-01A10001, R37 HL048058-14, P50 HL055006, P50 HL055006-100006, P01 HL084207-020001, P01 HL084207, P01 HL084207-02, R37 HL048058-15, P01 HL084207-01A1, R37 HL048058-13] Funding Source: Medline
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The renin-angiotensin system in the brain acts to regulate a number of physiological processes. Evidence suggests that angiotensin peptides may act as neurotransmitters, although their biosynthetic pathways are poorly understood. We review evidence for neuronal production of angiotensin peptides and hypothesize that angiotensin may be synthesized intracellularly in neurons.
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