Related references
Note: Only part of the references are listed.Bone Morphogenetic Proteins in Vascular Homeostasis and Disease
Marie-Jose Goumans et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2018)
Bone Morphogenetic Protein-Based Therapeutic Approaches
Jonathan W. Lowery et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2018)
Signaling Cross Talk between TGF-beta/Smad and Other Signaling Pathways
Kunxin Luo
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)
Regulation of TGF-β Family Signaling by Inhibitory Smads
Keiji Miyazawa et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)
Alternative cleavage of the bone morphogenetic protein (BMP), Gbb, produces ligands with distinct developmental functions and receptor preferences
Edward N. Anderson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass
Brian C. Goh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Bone Morphogenetic Protein
Eric A. Barcak et al.
ORTHOPEDIC CLINICS OF NORTH AMERICA (2017)
BmpR1A is a major type 1 BMP receptor for BMP-Smad signaling during skull development
Haichun Pan et al.
DEVELOPMENTAL BIOLOGY (2017)
Combinatorial Signal Perception in the BMP Pathway
Yaron E. Antebi et al.
CELL (2017)
Bone Morphogenetic Protein (BMP) signaling in animal reproductive system development and function
Amaneet K. Lochab et al.
DEVELOPMENTAL BIOLOGY (2017)
Bone morphogenetic proteins in inflammation, glucose homeostasis and adipose tissue energy metabolism
Lovorka Grgurevic et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2016)
Transient Local Bone Remodeling Effects of rhBMP-2 in an Ovine Interbody Spine Fusion Model
Hyun W. Bae et al.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME (2016)
BMP signalling in skeletal development, disease and repair
Valerie S. Salazar et al.
NATURE REVIEWS ENDOCRINOLOGY (2016)
Agonists and Antagonists of TGF-β Family Ligands
Chenbei Chang
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)
Bone Morphogenetic Proteins
Takenobu Katagiri et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)
Epidemiology of Fracture Nonunion in 18 Human Bones
Robert Zura et al.
JAMA SURGERY (2016)
A Survey of Strategies to Modulate the Bone Morphogenetic Protein Signaling Pathway: Current and Future Perspectives
Jonathan W. Lowery et al.
STEM CELLS INTERNATIONAL (2016)
Bone healing in 2016
John A. Buza et al.
CLINICAL CASES IN MINERAL AND BONE METABOLISM (2016)
TGF-β and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and disease
Mengrui Wu et al.
BONE RESEARCH (2016)
The history and histology of bone morphogenetic protein
Samuel S. Murray et al.
HISTOLOGY AND HISTOPATHOLOGY (2016)
Bmp2 conditional knockout in osteoblasts and endothelial cells does not impair bone formation after injury or mechanical loading in adult mice
Sarah Howe McBride-Gagyi et al.
BONE (2015)
BMP-Smad4 signaling is required for precartilaginous mesenchymal condensation independent of Sox9 in the mouse
Joohyun Lim et al.
DEVELOPMENTAL BIOLOGY (2015)
The Type I BMP Receptor ACVR1/ALK2 is Required for Chondrogenesis During Development
Diana Rigueur et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2015)
Loss of BMPR2 leads to high bone mass due to increased osteoblast activity
Jonathan W. Lowery et al.
JOURNAL OF CELL SCIENCE (2015)
The prodomain of BMP4 is necessary and sufficient to generate stable BMP4/7 heterodimers with enhanced bioactivity in vivo
Judith M. Neugebauer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Neofunction of ACVR1 in fibrodysplasia ossificans progressiva
Kyosuke Hino et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Expression and purification of active recombinant human bone morphogenetic 7-2 dimer fusion protein
Jianli Dang et al.
PROTEIN EXPRESSION AND PURIFICATION (2015)
ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A
Sarah J. Hatsell et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
The bone morphogenetic protein-2/7 heterodimer is a stronger inducer of bone regeneration than the individual homodimers in a rat spinal fusion model
Tokimitsu Morimoto et al.
SPINE JOURNAL (2015)
Dynamics and Cellular Localization of Bmp2, Bmp4, and Noggin Transcription in the Postnatal Mouse Skeleton
Steven K. Pregizer et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2015)
MicroRNA-302a Stimulates Osteoblastic Differentiation by Repressing COUP-TFII Expression
In-Hong Kang et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2015)
Systemic Injection of CK2.3, a Novel Peptide Acting Downstream of Bone Morphogenetic Protein Receptor BMPRIa, Leads to Increased Trabecular Bone Mass
Hemanth Akkiraju et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2015)
Fracture healing: mechanisms and interventions
Thomas A. Einhorn et al.
NATURE REVIEWS RHEUMATOLOGY (2015)
Bone Morphogenetic Protein for the Healing of Tibial Fracture: A Meta-Analysis of Randomized Controlled Trials
Jiezhi Dai et al.
PLOS ONE (2015)
TGF-β/BMP signaling and other molecular events: regulation of osteoblastogenesis and bone formation
Md Shaifur Rahman et al.
BONE RESEARCH (2015)
Mesenchymal stem cells from osteoporotic patients reveal reduced migration and invasion upon stimulation with BMP-2 or BMP-7
Florian Haasters et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
A myostatin and activin decoy receptor enhances bone formation in mice
P. Bialek et al.
BONE (2014)
BMP-2 and titanium particles synergistically activate osteoclast formation
S. X. Sun et al.
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (2014)
Systemically available bone morphogenetic protein two and seven affect bone metabolism
Ivo Dumic-Cule et al.
INTERNATIONAL ORTHOPAEDICS (2014)
GATA4 is Essential for Bone Mineralization via ERα and TGFβ/BMP Pathways
Miriam Gueemes et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2014)
Ligand- and Stage-Dependent Divergent Functions of BMP Signaling in the Differentiation of Embryonic Skeletogenic Progenitors In Vitro
Carlos I. Lorda-Diez et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2014)
The Recent Prevalence of Osteoporosis and Low Bone Mass in the United States Based on Bone Mineral Density at the Femoral Neck or Lumbar Spine
Nicole C. Wright et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2014)
Optimizing the osteogenic differentiation of human mesenchymal stromal cells by the synergistic action of growth factors
Yahya Acil et al.
JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY (2014)
Bone substitutes in orthopaedic surgery: from basic science to clinical practice
V. Campana et al.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE (2014)
An Antibody Blocking Activin Type II Receptors Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy
Estelle Lach-Trifilieff et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
BMP activation and Wnt-signalling affect biochemistry and functional biomechanical properties of cartilage tissue engineering constructs
A. Krase et al.
OSTEOARTHRITIS AND CARTILAGE (2014)
Long Bone Structure and Strength Depend on BMP2 from Osteoblasts and Osteocytes, but Not Vascular Endothelial Cells
Sarah H. McBride et al.
PLOS ONE (2014)
Regulation of TGFβ and related signals by precursor processing
Daniel B. Constam
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2014)
Expansion of Murine Periosteal Progenitor Cells with Fibroblast Growth Factor 2 Reveals an Intrinsic Endochondral Ossification Program Mediated by Bone Morphogenetic Protein 2
Nick van Gastel et al.
STEM CELLS (2014)
miR-542-3p suppresses osteoblast cell proliferation and differentiation, targets BMP-7 signaling and inhibits bone formation
J. Kureel et al.
CELL DEATH & DISEASE (2014)
Selective Small Molecule Compounds Increase BMP-2 Responsiveness by Inhibiting Smurf1-mediated Smad1/5 Degradation
Yu Cao et al.
SCIENTIFIC REPORTS (2014)
Smad9 is a new type of transcriptional regulator in bone morphogenetic protein signaling
S. Tsukamoto et al.
SCIENTIFIC REPORTS (2014)
Bone regenerative medicine: classic options, novel strategies, and future directions
Ahmad Oryan et al.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH (2014)
Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis
Amanda B. Core et al.
FRONTIERS IN PHARMACOLOGY (2014)
Interactions between FGF21 and BMP-2 in osteogenesis
Kazunari Ishida et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Mesenchymal stem cells from osteoporotic patients feature impaired signal transduction but sustained osteoinduction in response to BMP-2 stimulation
Wolf Christian Prall et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
New insights in osteogenic differentiation revealed by mass spectrometric assessment of phosphorylated substrates in murine skin mesenchymal cells
Erik Halcsik et al.
BMC CELL BIOLOGY (2013)
Activins bind and signal via bone morphogenetic protein receptor type II (BMPR2) in immortalized gonadotrope-like cells
Carlis A. Rejon et al.
CELLULAR SIGNALLING (2013)
Bone morphogenetic protein-9 activates Smad and ERK pathways and supports human osteoclast function and survival in vitro
David Fong et al.
CELLULAR SIGNALLING (2013)
Smad7 regulates terminal maturation of chondrocytes in the growth plate
Kristine D. Estrada et al.
DEVELOPMENTAL BIOLOGY (2013)
Effects of the activin A-myostatin-follistatin system on aging bone and muscle progenitor cells
Matthew Bowser et al.
EXPERIMENTAL GERONTOLOGY (2013)
Chondrocyte BMP2 signaling plays an essential role in bone fracture healing
Meng Mi et al.
GENE (2013)
Marker Gene Screening for Human Mesenchymal Stem Cells in Early Osteogenic Response to Bone Morphogenetic Protein 6 with DNA Microarray
Shien Zou et al.
GENETIC TESTING AND MOLECULAR BIOMARKERS (2013)
Fibroblast growth factor 2 inhibits bone morphogenetic protein 9-induced osteogenic differentiation of mesenchymal stem cells by repressing Smads signaling and subsequently reducing Smads dependent up-regulation of ALK1 and ALK2
Tao Song et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2013)
Bone Morphogenetic Proteins Signal Via SMAD and Mitogen-activated Protein (MAP) Kinase Pathways at Distinct Times during Osteoclastogenesis
Aaron Broege et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Postnatal ablation of osteoblast Smad4 enhances proliferative responses to canonical Wnt signaling through interactions with β-catenin
Valerie S. Salazar et al.
JOURNAL OF CELL SCIENCE (2013)
Embryonic ablation of osteoblast Smad4 interrupts matrix synthesis in response to canonical Wnt signaling and causes an osteogenesis-imperfecta-like phenotype
Valerie S. Salazar et al.
JOURNAL OF CELL SCIENCE (2013)
Bmp2 in osteoblasts of periosteum and trabecular bone links bone formation to vascularization and mesenchymal stem cells
Wuchen Yang et al.
JOURNAL OF CELL SCIENCE (2013)
Multiple-Dose, Safety, Pharmacokinetic, and Pharmacodynamic Study of Sotatercept (ActRIIA-IgG1), a Novel Erythropoietic Agent, in Healthy Postmenopausal Women
Matthew L. Sherman et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2013)
Noggin Resistance Contributes to the Potent Osteogenic Capability of BMP9 in Mesenchymal Stem Cells
Yi Wang et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2013)
Fibroblast Growth Factor-2 and Bone Morphogenetic Protein-2 Have a Synergistic Stimulatory Effect on Bone Formation in Cell Cultures From Elderly Mouse and Human Bone
Liisa T. Kuhn et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2013)
Activin A Suppresses Osteoblast Mineralization Capacity by Altering Extracellular Matrix (ECM) Composition and Impairing Matrix Vesicle (MV) Production
Rodrigo D. A. M. Alves et al.
MOLECULAR & CELLULAR PROTEOMICS (2013)
Expression profiling of lncRNAs in C3H10T1/2 mesenchymal stem cells undergoing early osteoblast differentiation
Changqing Zuo et al.
MOLECULAR MEDICINE REPORTS (2013)
Comparative Genomics Identifies the Mouse Bmp3 Promoter and an Upstream Evolutionary Conserved Region (ECR) in Mammals
Jonathan W. Lowery et al.
PLOS ONE (2013)
Pin1 Null Mice Exhibit Low Bone Mass and Attenuation of BMP Signaling
Zhong-Jian Shen et al.
PLOS ONE (2013)
Deficiency of Retinaldehyde Dehydrogenase 1 Induces BMP2 and Increases Bone Mass In Vivo
Shriram Nallamshetty et al.
PLOS ONE (2013)
Heterodimeric BMP-2/7 Antagonizes the Inhibition of All-Trans Retinoic Acid and Promotes the Osteoblastogenesis
Wenjuan Bi et al.
PLOS ONE (2013)
Beyond osteogenesis: an in vitro comparison of the potentials of six bone morphogenetic proteins
Jessica C. Rivera et al.
FRONTIERS IN PHARMACOLOGY (2013)
Fibroblast growth factor 2 inhibits up-regulation of bone morphogenic proteins and their receptors during osteoblastic differentiation of human mesenchymal stem cells
Emmanuel Biver et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Control of osteogenesis by the canonical Wnt and BMP pathways in vivo
Sylvain Marcellini et al.
BIOESSAYS (2012)
Skeletal Morphogenesis during Embryonic Development
Yingzi Yang
CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION (2012)
Smad4 is required to induce digit ray primordia and to initiate the aggregation and differentiation of chondrogenic progenitors in mouse limb buds
Jean-Denis Benazet et al.
DEVELOPMENT (2012)
Activin A and cardiovascular disease in type 2 diabetes mellitus
Thor Ueland et al.
DIABETES & VASCULAR DISEASE RESEARCH (2012)
Conditional Inactivation of Noggin in the Postnatal Skeleton Causes Osteopenia
Ernesto Canalis et al.
ENDOCRINOLOGY (2012)
Structural studies of the TGF-βs and their receptors - insights into evolution of the TGF-β superfamily
Andrew P. Hinck
FEBS LETTERS (2012)
Regulation of bone and cartilage development by network between BMP signalling and transcription factors
Riko Nishimura et al.
JOURNAL OF BIOCHEMISTRY (2012)
SMAD versus Non-SMAD Signaling Is Determined by Lateral Mobility of Bone Morphogenetic Protein (BMP) Receptors
Asja Guzman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Homeodomain Transcription Factors Regulate BMP-2-Induced Osteoactivin Transcription in Osteoblasts
Maneet Singh et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2012)
Functional redundancy of type II BMP receptor and type IIB activin receptor in BMP2-induced osteoblast differentiation
Hongbin Liu et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2012)
The roles of activin A and its binding protein, follistatin, in inflammation and tissue repair
David M. de Kretser et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2012)
BMP3 Suppresses Osteoblast Differentiation of Bone Marrow Stromal Cells via Interaction with Acvr2b
Shoichiro Kokabu et al.
MOLECULAR ENDOCRINOLOGY (2012)
Inhibition of Osteoclast Generation: A Novel Function of the Bone Morphogenetic Protein 7/Osteogenic Protein 1
Thomas Maurer et al.
MEDIATORS OF INFLAMMATION (2012)
The BMP2/7 heterodimer inhibits the human breast cancer stem cell subpopulation and bone metastases formation
J. T. Buijs et al.
ONCOGENE (2012)
A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength
Marc Baud'huin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Brief Review of Models of Ectopic Bone Formation
Michelle A. Scott et al.
STEM CELLS AND DEVELOPMENT (2012)
BMP2/7 Heterodimer Can Modulate All Cellular Events of the In Vitro RANKL-Mediated Osteoclastogenesis, Respectively, in Different Dose Patterns
Yuanna Zheng et al.
TISSUE ENGINEERING PART A (2012)
Regulation of TGF-β receptor activity
Fei Huang et al.
CELL AND BIOSCIENCE (2012)
Loss-of-function of ACVR1 in osteoblasts increases bone mass and activates canonical Wnt signaling through suppression of Wnt inhibitors SOST and DKK1
Nobuhiro Kamiya et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Time series gene expression profiling and temporal regulatory pathway analysis of BMP6 induced osteoblast differentiation and mineralization
Weijun Luo et al.
BMC SYSTEMS BIOLOGY (2011)
The myogenic transcriptional network
Shigetoshi Yokoyama et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2011)
Cooperative activity of noggin and gremlin 1 in axial skeleton development
David A. Stafford et al.
DEVELOPMENT (2011)
BMPR-II is Dispensable for Formation of the Limb Skeleton
Laura W. Gamer et al.
GENESIS (2011)
Divergent activities of osteogenic BMP2, and tenogenic BMP12 and BMP13 independent of receptor binding affinities
Stephen P. Berasi et al.
GROWTH FACTORS (2011)
Prodomains of Transforming Growth Factor β (TGFβ) Superfamily Members Specify Different Functions EXTRACELLULAR MATRIX INTERACTIONS AND GROWTH FACTOR BIOAVAILABILITY
Gerhard Sengle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Smad6 Is Essential to Limit BMP Signaling During Cartilage Development
Kristine D. Estrada et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2011)
Conditional Deletion of Bmpr1a in Differentiated Osteoclasts Increases Osteoblastic Bone Formation, Increasing Volume of Remodeling Bone in Mice
Mina Okamoto et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2011)
BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development
Bing Shu et al.
JOURNAL OF CELL SCIENCE (2011)
Integration of BMP, Wnt, and Notch Signaling Pathways in Osteoblast Differentiation
Grace L. Lin et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2011)
A synthetic compound that potentiates bone morphogenetic protein-2-induced transdifferentiation of myoblasts into the osteoblastic phenotype
Satoshi Kato et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2011)
Self-complementary AAV2.5-BMP2-coated Femoral Allografts Mediated Superior Bone Healing Versus Live Autografts in Mice With Equivalent Biomechanics to Unfractured Femur
Cemal Yazici et al.
MOLECULAR THERAPY (2011)
Smad1 plays an essential role in bone development and postnatal bone formation
M. Wang et al.
OSTEOARTHRITIS AND CARTILAGE (2011)
Interaction of TGFβ and BMP Signaling Pathways during Chondrogenesis
Bettina Keller et al.
PLOS ONE (2011)
Spatial Segregation of BMP/Smad Signaling Affects Osteoblast Differentiation in C2C12 Cells
Eva Heining et al.
PLOS ONE (2011)
Osteogenic Responses to Different Concentrations/Ratios of BMP-2 and bFGF in Bone Formation
Lei Wang et al.
ANNALS OF BIOMEDICAL ENGINEERING (2010)
Generation of a mouse model with expression of bone morphogenetic protein type II receptor lacking the cytoplasmic domain in osteoblasts
Chaozhe Yang et al.
SKELETAL BIOLOGY AND MEDICINE (2010)
Site-Specific PEGylation of Bone Morphogenetic Protein-2 Cysteine Analogues
Junli Hu et al.
BIOCONJUGATE CHEMISTRY (2010)
Treatment with a soluble receptor for activin improves bone mass and structure in the axial and appendicular skeleton of female cynomolgus macaques (Macaca fascicularis)
Roberto Jose Fajardo et al.
BONE (2010)
A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys
Sutada Lotinun et al.
BONE (2010)
Osteo-transcriptomics of human mesenchymal stem cells: Accelerated gene expression and osteoblast differentiation induced by vitamin D reveals c-MYC as an enhancer of BMP2-induced osteogenesis
Ester Piek et al.
BONE (2010)
BMP signaling in vascular development and disease
Jonathan W. Lowery et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2010)
A Soluble Activin Receptor Type IIB Prevents the Effects of Androgen Deprivation on Body Composition and Bone Health
Alan Koncarevic et al.
ENDOCRINOLOGY (2010)
Nephroblastoma Overexpressed (Nov) Inactivation Sensitizes Osteoblasts to Bone Morphogenetic Protein-2, But Nov Is Dispensable for Skeletal Homeostasis
Ernesto Canalis et al.
ENDOCRINOLOGY (2010)
Identification of a Key Residue Mediating Bone Morphogenetic Protein (BMP)-6 Resistance to Noggin Inhibition Allows for Engineered BMPs with Superior Agonist Activity
Kening Song et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Characterization of the Ligand Binding Functionality of the Extracellular Domain of Activin Receptor Type IIB
Dianne Sako et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
BMP2-activated Erk/MAP Kinase Stabilizes Runx2 by Increasing p300 Levels and Histone Acetyltransferase Activity
Ji Hae Jun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
rhBMP-2 Induces Transient Bone Resorption Followed by Bone Formation in a Nonhuman Primate Core-Defect Model
Howard J. Seeherman et al.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME (2010)
Wnt Inhibitors Dkk1 and Sost Are Downstream Targets of BMP Signaling Through the Type IA Receptor (BMPRIA) in Osteoblasts
Nobuhiro Kamiya et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Inhibition of TGF-β Signaling by 1D11 Antibody Treatment Increases Bone Mass and Quality In Vivo
James R. Edwards et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
Bone Morphogenic Protein 2 Directly Enhances Differentiation of Murine Osteoclast Precursors
Eric D. Jensen et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2010)
Virtual screening and selection of drug-like compounds to block noggin interaction with bone morphogenetic proteins
Shaila Ahmed et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2010)
Bone Morphogenetic Proteins 2, 5, and 6 in Combination Stimulate Osteoblasts but Not Osteoclasts In Vitro
Arno Wutzl et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2010)
Bone Morphogenetic Protein-2 and-6 Heterodimer Illustrates the Nature of Ligand-Receptor Assembly
Michael J. Isaacs et al.
MOLECULAR ENDOCRINOLOGY (2010)
BMP-2/6 Heterodimer Is More Effective than BMP-2 or BMP-6 Homodimers as Inductor of Differentiation of Human Embryonic Stem Cells
Elvira Valera et al.
PLOS ONE (2010)
Extracellular BMP-antagonist regulation in development and disease: tied up in knots
David W. Walsh et al.
TRENDS IN CELL BIOLOGY (2010)
Receptor oligomerization and beyond: a case study in bone morphogenetic proteins
Kai Heinecke et al.
BMC BIOLOGY (2009)
New insights into BMP-7 mediated osteoblastic differentiation of primary human mesenchymal stem cells
Karen Lavery et al.
BONE (2009)
Development and optimization of a cell-based assay for the selection of synthetic compounds that potentiate bone morphogenetic protein-2 activity
Motohiro Okada et al.
CELL BIOCHEMISTRY AND FUNCTION (2009)
Activin and related proteins in inflammation: Not just interested bystanders
David J. Phillips et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2009)
BMP2 signaling in bone development and repair
Vicki Rosen
CYTOKINE & GROWTH FACTOR REVIEWS (2009)
BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation
Kelsey N. Retting et al.
DEVELOPMENT (2009)
Endogenous bone morphogenetic proteins in human bone marrow-derived multipotent mesenchymal stromal cells
F. Philipp Seib et al.
EUROPEAN JOURNAL OF CELL BIOLOGY (2009)
A comparative study on BMP-induced osteoclastogenesis and osteoblastogenesis in primary cultures of adult rat bone marrow cells
Sangita Paul et al.
GROWTH FACTORS (2009)
Molecular Regulation of Matrix Extracellular Phosphoglycoprotein Expression by Bone Morphogenetic Protein-2
Young-Dan Cho et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Enhanced Osteoclastogenesis Causes Osteopenia in Twisted Gastrulation-Deficient Mice Through Increased BMP Signaling
Julio E. Sotillo Rodriguez et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2009)
Sustained BMP Signaling in Osteoblasts Stimulates Bone Formation by Promoting Angiogenesis and Osteoblast Differentiation
Fengjie Zhang et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2009)
Single-Dose, Randomized, Double-Blind, Placebo-Controlled Study of ACE-011 (ActRIIA-IgG1) in Postmenopausal Women
Jon Ruckle et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2009)
Axin2 controls bone remodeling through the β-catenin-BMP signaling pathway in adult mice
Ying Yan et al.
JOURNAL OF CELL SCIENCE (2009)
Sustained and Localized In Vitro Release of BMP-2/7, RANKL, and Tetracycline from FlexBone, an Elastomeric Osteoconductive Bone Substitute
Jianwen Xu et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2009)
'Two-Stage Double-Technique Hybrid (TSDTH)' Identification Strategy for the Analysis of BMP2-Induced Transdifferentiation of Premyoblast C2C12 Cells to Osteoblast
Byung-Gyu Kim et al.
JOURNAL OF PROTEOME RESEARCH (2009)
Id1 Represses Osteoclast-Dependent Transcription and Affects Bone Formation and Hematopoiesis
April S. Chan et al.
PLOS ONE (2009)
Expression, purification and osteogenic bioactivity of recombinant human BMP-4,-9,-10,-11 and-14
P. C. Bessa et al.
PROTEIN EXPRESSION AND PURIFICATION (2009)
Short-term Osteoclastic Activity Induced by Locally High Concentrations of Recombinant Human Bone Morphogenetic Protein-2 in a Cancellous Bone Environment
Jeffrey M. Toth et al.
SPINE (2009)
A Comprehensive Analysis of the Dual Roles of BMPs in Regulating Adipogenic and Osteogenic Differentiation of Mesenchymal Progenitor Cells
Quan Kang et al.
STEM CELLS AND DEVELOPMENT (2009)
BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway
Nobuhiro Kamiya et al.
DEVELOPMENT (2008)
BMP4 is dispensable for skeletogenesis and fracture-healing in the limb
Kunikazu Tsuji et al.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME (2008)
Osteocyte-derived sclerostin inhibits bone formation:: Its role in bone morphogenetic protein and Wnt signaling
Peter ten Dijke et al.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME (2008)
Disruption of BMP Signaling in Osteoblasts Through Type IA Receptor (BMPRIA) Increases Bone Mass
Nobuhiro Kamiya et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2008)
Reduced expression and function of bone morphogenetic protein-2 in bones of Fgf2 null mice
Takahiro Naganawa et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2008)
A new model for growth factor activation:: Type II receptors compete with the prodomain for BMP-7
Gerhard Sengle et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Accelerated hypertrophic chondrocyte kinetics in GDF-7 deficient murine tibial growth plates
Borjana Mikic et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2008)
Cooperative assembly of TGF-β superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding
Jay Groppe et al.
MOLECULAR CELL (2008)
SMAD proteins control DROSHA-mediated microRNA maturation
Brandi N. Davis et al.
NATURE (2008)
BMP type I receptor inhibition reduces heterotopic ossification
Paul B. Yu et al.
NATURE MEDICINE (2008)
A soluble activin type IIA receptor induces bone formation and improves skeletal integrity
R. Scott Pearsall et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
A microRNA signature for a BMP2-induced osteoblast lineage commitment program
Zhaoyong Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Effects of low intensity pulsed ultrasound with and without increased cortical porosity on structural bone allograft incorporation
Brandon G Santoni et al.
Journal of Orthopaedic Surgery and Research (2008)
Identification of novel Runx2 targets in osteoblasts:: Cell type-specific BMP-dependent regulation of Tram2
Steven Pregizer et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
BMP-3 and BMP-6 structures illuminate the nature of binding specificity with receptors
George P. Allendorph et al.
BIOCHEMISTRY (2007)
Conditional deletion of gremlin causes a transient increase in bone formation and bone mass
Elisabetta Gazzerro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The activin A-follistatin system: potent regulator of human extracellular matrix mineralization
Marco Eijken et al.
FASEB JOURNAL (2007)
Recent advances in gene delivery for structural bone allografts
Hani A. Awad et al.
TISSUE ENGINEERING (2007)
Nephroblastoma overexpressed (Nov) inhibits osteoblastogenesis and causes osteopenia
Sheila Rydziel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Smad4 is required for maintaining normal murine postnatal bone homeostasis
Xiaohong Tan et al.
JOURNAL OF CELL SCIENCE (2007)
Distinct roles of bone morphogenetic proteins in osteogenic differentiation of mesenchymal stem cells
Hue H. Luu et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2007)
Bone morphogenetic protein 2 activates Smad6 gene transcription through bone-specific transcription factor Runx2
Qing Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Inhibin A is an endocrine stimulator of bone mass and strength
Daniel S. Perrien et al.
ENDOCRINOLOGY (2007)
BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network
Mohammad Q. Hassan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing
Kunikazu Tsuji et al.
NATURE GENETICS (2006)
Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis
Amitabha Bandyopadhyay et al.
PLOS GENETICS (2006)
Twisted gastrulation, a bone morphogenetic protein agonist/antagonist, is not required for post-natal skeletal function
Elisabetta Gazzerro et al.
BONE (2006)
Systemically administered bone morphogenetic protein-6 restores bone in aged ovariectomized rats by increasing bone formation and suppressing bone resorption
Petra Simic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
BMP receptor type IA in limb bud mesenchyrne regulates distal outgrowth and patterning
Dmitry A. Ovchinnikov et al.
DEVELOPMENTAL BIOLOGY (2006)
Structure of the ternary signaling complex of a TGF-β superfamily member
George P. Allendorph et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Expression and regulation of CCN genes in murine osteoblasts
Muriel S. Parisi et al.
BONE (2006)
Bone morphogenetic proteins 5 and 6 stimulate osteoclast generation
A Wutzl et al.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2006)
Expression of the human activin type I and II receptor extracellular domains in Pichia pastoris
R Daly et al.
PROTEIN EXPRESSION AND PURIFICATION (2006)
Critical molecular switches involved in BMP-2-induced osteogenic differentiation of mesenchymal cells
HM Ryoo et al.
GENE (2006)
Noggin antagonism of BMP4 signaling controls development of the axial skeleton in the mouse
M Wijgerde et al.
DEVELOPMENTAL BIOLOGY (2005)
BMP-3 is a novel inhibitor of both activin and BMP-4 signaling in Xenopus embryos
LW Gamer et al.
DEVELOPMENTAL BIOLOGY (2005)
Smad4 is required for the normal organization of the cartilage growth plate
JH Zhang et al.
DEVELOPMENTAL BIOLOGY (2005)
BMP signaling and early embryonic patterning
S Kishigami et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2005)
Osx transcriptional regulation is mediated by additional pathways to BMP2/Smad signaling
AB Celil et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2005)
Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo
BS Yoon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Skeletal overexpression of gremlin impairs bone formation and causes osteopenia
E Gazzerro et al.
ENDOCRINOLOGY (2005)
A flexible activin explains the membrane-dependent cooperative assembly of TGF-β family receptors
J Greenwald et al.
MOLECULAR CELL (2004)
Inhibins, activins, and follistatin in the aging female and male
JM Hurwitz et al.
SEMINARS IN REPRODUCTIVE MEDICINE (2004)
Inhibitor of DNA binding/differentiation helix-loop-helix proteins mediate bone morphogenetic protein-induced osteoblast differentiation of mesenchymal stem cells
Y Peng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells:: the role of PPAR-γ2 transcription factor and TGF-β/BMP signaling pathways
EJ Moerman et al.
AGING CELL (2004)
Bone morphogenetic protein type IA receptor signaling regulates postnatal osteoblast function and bone remodeling
Y Mishina et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Identification of novel regulators associated with early-phase osteoblast differentiation
DS de Jong et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2004)
Inhibitory helix-loop-helix transcription factors Id1/Id3 promote bone formation in vivo
Y Maeda et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2004)
Transcriptional characterization of bone morphogenetic proteins (BMPs)-mediated osteogenic signaling
Y Peng et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2003)
Myostatin signals through a transforming growth factor β-like signaling pathway to block adipogenesis
A Rebbapragada et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
BMP-2-induced Osterix expression is mediated by Dlx5 but is independent of Runx2
MH Lee et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Transcriptional regulation of BMP-2 activated genes in osteoblasts using gene expression microarray analysis: Role of DLX2 and DLX5 transcription factors
SE Harris et al.
FRONTIERS IN BIOSCIENCE (2003)
Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs)
HW Cheng et al.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME (2003)
Id proteins in development, cell cycle and cancer
MB Ruzinova et al.
TRENDS IN CELL BIOLOGY (2003)
Transcriptional regulation of the human Runx2/Cbfa1 gene promoter by bone morphogenetic protein-7
LQ Tou et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2003)
Gene array analysis of bone morphogenetic protein type I receptor-induced osteoblast differentiation
O Korchynskyi et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2003)
Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning
MK Khokha et al.
NATURE GENETICS (2003)
Sclerostin is a novel secreted osteoclast-derived bone morphogenetic protein antagonist with unique ligand specificity
N Kusu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Phenotype discovery by gene expression profiling: Mapping of biological processes linked to BMP-2-mediated osteoblast differentiation
E Balint et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2003)
Skeletal overexpression of noggin results in osteopenia and reduced bone formation
RD Devlin et al.
ENDOCRINOLOGY (2003)
Bone morphogenetic proteins, their antagonists, and the skeleton
E Canalis et al.
ENDOCRINE REVIEWS (2003)
The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly
J Greenwald et al.
MOLECULAR CELL (2003)
Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes
SH Settle et al.
DEVELOPMENTAL BIOLOGY (2003)
Initiation of Smad-dependent and Smad-independent signaling via distinct BMP-receptor complexes
S Hassel et al.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME (2003)
BMP signaling is required for septation of the outflow tract of the mammalian heart
EC Delot et al.
DEVELOPMENT (2003)
Osteocyte control of bone formation via sclerostin, a novel BMP antagonist
DG Winkler et al.
EMBO JOURNAL (2003)
Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot
J Laurikkala et al.
DEVELOPMENTAL BIOLOGY (2003)
Microarray analysis of bone morphogenetic protein, transforming growth factor β, and activin early response genes during osteoblastic cell differentiation
DS De Jong et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2002)
Bone morphogenetic protein receptor signaling is necessary for normal murine postnatal bone formation
M Zhao et al.
JOURNAL OF CELL BIOLOGY (2002)
Expression of Cre recombinase in the developing mouse limb bud driven by a Prxl enhancer
M Logan et al.
GENESIS (2002)
α2-HS glycoprotein/fetuin, a transforming growth factor-β/bone morphogenetic protein antagonist, regulates postnatal bone growth and remodeling
M Szweras et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways
A Nohe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Systemically administered rhBMP-2 promotes MSC activity and reverses bone and cartilage loss in osteopenic mice
G Turgeman et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2002)
Role of TGF-beta family in osteoclastogenesis induced by RANKL
T Koseki et al.
CELLULAR SIGNALLING (2002)
Assessment of gene regulation by bone morphogenetic protein 2 in human marrow stromal cells using gene array technology
RM Locklin et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2001)
Activin A serum levels and aging of the pituitary-gonadal axis: a cross-sectional study in middle-aged and elderly healthy subjects
A Baccarelli et al.
EXPERIMENTAL GERONTOLOGY (2001)
Cooperativity of binding epitopes and receptor chains in the BMP/TGFβ superfamily
P Knaus et al.
BIOLOGICAL CHEMISTRY (2001)
Characterization of the upstream mouse Cbfa1/Runx2 promoter
ZS Xiao et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2001)
Bone morphogenetic protein-3 is a negative regulator of bone density
A Daluiski et al.
NATURE GENETICS (2001)
Essential requirement of BMPs-2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: Antagonism by noggin
E Abe et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2000)
Runx2 is a common target of transforming growth factor β1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12
KS Lee et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Direct stimulation of osteoclastic bone resorption by bone morphogenetic protein (BMP)-2 and expression of BMP receptors in mature osteoclasts
H Kaneko et al.
BONE (2000)
BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II
T Kirsch et al.
EMBO JOURNAL (2000)
Share Paper
