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Nora Kloeting et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2010)
Lipopolysaccharide, high glucose and saturated fatty acids induce endoplasmic reticulum stress in cultured primary human adipocytes: Salicylate alleviates this stress
Saif Alhusaini et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Fat cell turnover in humans
Peter Arner et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2
Stefania Mitola et al.
BLOOD (2010)
Adipocyte Turnover: Relevance to Human Adipose Tissue Morphology
Erik Arner et al.
DIABETES (2010)
Pro-Inflammatory CD11c+CD206+ Adipose Tissue Macrophages Are Associated With Insulin Resistance in Human Obesity
John M. Wentworth et al.
DIABETES (2010)
Regional impact of adipose tissue morphology on the metabolic profile in morbid obesity
J. Hoffstedt et al.
DIABETOLOGIA (2010)
Saturated- and n-6 Polyunsaturated-Fat Diets Each Induce Ceramide Accumulation in Mouse Skeletal Muscle: Reversal and Improvement of Glucose Tolerance by Lipid Metabolism Inhibitors
G. Frangioudakis et al.
ENDOCRINOLOGY (2010)
Adipocyte size predicts incidence of type 2 diabetes in women
Malin Lonn et al.
FASEB JOURNAL (2010)
Adipose tissue as an endocrine organ
Sandra Galic et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2010)
Angiogenesis and development of adipose tissue
V. Christiaens et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2010)
Transcriptional control of preadipocyte determination by Zfp423
Rana K. Gupta et al.
NATURE (2010)
Vascular endothelial growth factor B controls endothelial fatty acid uptake
Carolina E. Hagberg et al.
NATURE (2010)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
Elizabeth K. Speliotes et al.
NATURE GENETICS (2010)
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
Fabio Martinon et al.
NATURE IMMUNOLOGY (2010)
Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases
Yihai Cao
NATURE REVIEWS DRUG DISCOVERY (2010)
Hyperglycemia-induced endoplasmic reticulum stress in endothelial cells
Mae Sheikh-Ali et al.
NUTRITION (2010)
Traditional Anthropometric Parameters Still Predict Metabolic Disorders in Women With Severe Obesity
Severine Ledoux et al.
OBESITY (2010)
The Relationship of Omental and Subcutaneous Adipocyte Size to Metabolic Disease in Severe Obesity
Jean O'Connell et al.
PLOS ONE (2010)
Evidence for a Relationship between VEGF and BMI Independent of Insulin Sensitivity by Glucose Clamp Procedure in a Homogenous Group Healthy Young Men
Michaela Loebig et al.
PLOS ONE (2010)
Regional differences in cellular mechanisms of adipose tissue gain with overfeeding
Yourka D. Tchoukalova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Two New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for Early-Onset Extreme Obesity in French and German Study Groups
Andre Scherag et al.
PLOS GENETICS (2010)
CCN5, a secreted protein, localizes to the nucleus
Kristina C. Wiesman et al.
JOURNAL OF CELL COMMUNICATION AND SIGNALING (2010)
Inflammation and impaired adipogenesis in hypertrophic obesity in man
Birgit Gustafson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Role of hypoxia in obesity-induced disorders of glucose and lipid metabolism in adipose tissue
Jun Yin et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Role of Insulin Resistance and Lipotoxicity in Non-Alcoholic Steatohepatitis
Kenneth Cusi
CLINICS IN LIVER DISEASE (2009)
Hypoxia Decreases Insulin Signaling Pathways in Adipocytes
Claire Regazzetti et al.
DIABETES (2009)
Endoplasmic Reticulum Stress Is Reduced in Tissues of Obese Subjects After Weight Loss
Margaret F. Gregor et al.
DIABETES (2009)
Reduced Adipose Tissue Oxygenation in Human Obesity Evidence for Rarefaction, Macrophage Chemotaxis, and Inflammation Without an Angiogenic Response
Magdalena Pasarica et al.
DIABETES (2009)
Changes in Insulin Sensitivity and Insulin Release in Relation to Glycemia and Glucose Tolerance in 6,414 Finnish Men
Alena Stancakova et al.
DIABETES (2009)
Impaired Preadipocyte Differentiation in Human Abdominal Obesity Role of Wnt, Tumor Necrosis Factor-α, and Inflammation
Petter Isakson et al.
DIABETES (2009)
High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans Effects of Cold Exposure and Adiposity
Masayuki Saito et al.
DIABETES (2009)
Lower Total Adipocyte Number but No Evidence for Small Adipocyte Depletion in Patients With Type 2 Diabetes
Magdalena Pasarica et al.
DIABETES CARE (2009)
Markers of de novo lipogenesis in adipose tissue: associations with small adipocytes and insulin sensitivity in humans
R. Roberts et al.
DIABETOLOGIA (2009)
Obesity and Cancer Part 1 of the Diabetes and Cancer Mini-Review Series
R. Percik et al.
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES (2009)
Mechanisms of obesity and related pathologies: The macro- and microcirculation of adipose tissue
Joseph M. Rutkowski et al.
FEBS JOURNAL (2009)
Intramuscular Lipid Metabolism, Insulin Action, and Obesity
Leslie A. Consitt et al.
IUBMB LIFE (2009)
Uncoupling Protein-1 and Related Messenger Ribonucleic Acids in Human Epicardial and Other Adipose Tissues: Epicardial Fat Functioning as Brown Fat
Harold S. Sacks et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
Kupffer cells in non-alcoholic fatty liver disease: The emerging view
Gyoergy Baffy
JOURNAL OF HEPATOLOGY (2009)
Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue
Nils Halberg et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Brief Report: Functional Brown Adipose Tissue in Healthy Adults.
Kirsi A. Virtanen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Cold-Activated Brown Adipose Tissue in Healthy Men
Wouter D. van Marken Lichtenbelt et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Identification and Importance of Brown Adipose Tissue in Adult Humans.
Aaron M. Cypess et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Adipogenesis and WNT signalling
Constantinos Christodoulides et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2009)
Subcutaneous adipocyte size and body fat distribution
Yourka D. Tchoukalova et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2008)
Enhanced angiogenesis in obesity and in response to PPARγ activators through adipocyte VEGF and ANGPTL4 production
Olga Gealekman et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
Exercise-induced alterations in intramyocellular lipids and insulin resistance:: the athlete's paradox revisited
John J. Dube et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
Fat and beyond: The diverse biology of PPAR gamma
Peter Tontonoz et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2008)
The obese without cardiometabolic risk factor clustering and the normal weight with cardiometabolic risk factor clustering - Prevalence and correlates of 2 phenotypes among the US population (NHANES 1999-2004)
Rachel P. Wildman et al.
ARCHIVES OF INTERNAL MEDICINE (2008)
White Adipose Tissue as Endocrine Organ and Its Role in Obesity
Maria Eugenia Frigolet Vazquez-Vela et al.
ARCHIVES OF MEDICAL RESEARCH (2008)
Angiogenesis and obesity
H. Roger Lijnen
CARDIOVASCULAR RESEARCH (2008)
Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals
Guenther Boden et al.
DIABETES (2008)
Angiogenesis Associated With Visceral and Subcutaneous Adipose Tissue in Severe Human Obesity
Severine Ledoux et al.
DIABETES (2008)
Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes
Carey N. Lumeng et al.
DIABETES (2008)
Early hematopoietic zinc finger protein-zinc finger protein 521: A candidate regulator of diverse immature cells
Heather M. Bond et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2008)
Endoplasmic Reticulum Stress Markers Are Associated with Obesity in Nondiabetic Subjects
Neeraj K. Sharma et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
Dynamics of fat cell turnover in humans
Kirsty L. Spalding et al.
NATURE (2008)
New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
Yu-Hua Tseng et al.
NATURE (2008)
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
Adilson Guilherme et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Defining Stem and Progenitor Cells within Adipose Tissue
Guiting Lin et al.
STEM CELLS AND DEVELOPMENT (2008)
Mutations in ligands and receptors of the leptin-melanocortin pathway that lead to obesity
I. Sadaf Farooqi et al.
NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM (2008)
Multipotential human adipose-derived stromal stem cells exhibit a perivascular phenotype in vitro and in vivo
A. C. W. Zannettino et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2008)
BMPs promote proliferation and migration of endothelial cells via stimulation of VEGF-A/VEGFR2 and Angiopoietin-1/Tie2 signalling
Yuka Suzuki et al.
JOURNAL OF BIOCHEMISTRY (2008)
Obesity-associated improvements in metabolic profile through expansion of adipose tissue
Ja-Young Kim et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
PPARγ activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties
M. Amine Bouhlel et al.
CELL METABOLISM (2007)
Enhanced proportion of small adipose cells in insulin-resistant vs insulin-sensitive obese individuals implicates impaired adipogenesis
T. McLaugblin et al.
DIABETOLOGIA (2007)
Functional implication of BMP4 expression on angiogenesis in malignant melanoma
T. Rothhammer et al.
ONCOGENE (2007)
Comparative studies of the role of hormone-sensitive lipase and adipose triglyceride lipase in human fat cell lipolysis
Mikael Ryden et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
Adipogenesis in obesity requires close interplay between differentiating adipocytes, strontal cells, and blood vessels
Satoshi Nishimura et al.
DIABETES (2007)
The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARγ expression
Hironori Waki et al.
CELL METABOLISM (2007)
NF-κB is important for TNF-α-induced lipolysis in human adipocytes
Jurga Laurencikiene et al.
JOURNAL OF LIPID RESEARCH (2007)
Relationship between adipocyte size and adipokine expression and secretion
Thomas Skurk et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)
Fat cell enlargement is an independent marker of insulin resistance and 'hyperleptinaemia'
M. Lundgren et al.
DIABETOLOGIA (2007)
Inhibition of protein kinase Cε prevents hepatic insulin resistance in nonalcoholic fatty liver disease
Varman T. Samuel et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Interleukin-1 beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression
Jennifer Jager et al.
ENDOCRINOLOGY (2007)
Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade
Maria A. Jimenez et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity
Carey N. Lumeng et al.
DIABETES (2007)
Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation
Naomi Hosogai et al.
DIABETES (2007)
Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor
Helena Stabile et al.
BLOOD (2007)
Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acid-induced skeletal muscle insulin resistance in vitro
S. K. Pinnamaneni et al.
DIABETOLOGIA (2006)
TLR4 links innate immunity and fatty acid-induced insulin resistance
Hang Shi et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Adipocytokines: mediators linking adipose tissue, inflammation and immunity
Herbert Tilg et al.
NATURE REVIEWS IMMUNOLOGY (2006)
Transcriptional control of adipocyte formation
Stephen R. Farmer
CELL METABOLISM (2006)
Non-DNA binding, dominant-negative, human PPARγ mutations cause lipodystrophic insulin resistance
Maura Agostini et al.
CELL METABOLISM (2006)
Stable stem cell commitment to the adipocyte lineage by inhibition of DNA methylation: Role of the BMP-4 gene
Robert R. Bowers et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Regulation of bone mass by Wnt signaling
V Krishnan et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Nonalcoholic fatty liver disease: Cytokine-adipokine interplay and regulation of insulin resistance
Herbert Tilg et al.
GASTROENTEROLOGY (2006)
Production of chemokines by perivascular adipose tissue - A role in the pathogenesis of atherosclerosis?
E Henrichot et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)
Link between obesity and type 2 diabetes
A Golay et al.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
Specific inhibition of hormone-sensitive lipase improves lipid profile while reducing plasma glucose
TH Claus et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery induced weight loss
R Cancello et al.
DIABETES (2005)
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
Q Yang et al.
NATURE (2005)
Sequential phosphorylation of CCAAT enhancer-binding protein β by MAPK and glycogen synthase kinase 3β is required for adipogenesis
QQ Tang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy
UB Pajvani et al.
NATURE MEDICINE (2005)
Adiponectin: Identification, physiology and clinical relevance in metabolic and vascular disease
Y Matsuzawa
ATHEROSCLEROSIS SUPPLEMENTS (2005)
Considerable disturbances of cardiovascular risk factors in women with diabetes and myocardial infarction
A Dotevall et al.
JOURNAL OF DIABETES AND ITS COMPLICATIONS (2005)
Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity
UB Pajvani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
High local concentrations and effects on differentiation implicate interleukin-6 as a paracrine regulator
VR Sopasakis et al.
OBESITY RESEARCH (2004)
Role of CREB in transcriptional regulation of CCAAT/enhancer-binding protein β gene during adipogenesis
JW Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Obesity decreases perioperative tissue oxygenation
B Kabon et al.
ANESTHESIOLOGY (2004)
Metabolic syndrome in normal-weight Americans - New definition of the metabolically obese, normal-weight individual
MP St-Onge et al.
DIABETES CARE (2004)
Ovarian hormone status and abdominal visceral adipose tissue metabolism
A Tchernof et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Ceramide content is increased in skeletal muscle from obese insulin-resistant humans
JM Adams et al.
DIABETES (2004)
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
U Özcan et al.
SCIENCE (2004)
Evidence of impaired adipogenesis in insulin resistance
XL Yang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle
WM He et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-α, overexpressed in human fat cells from insulin-resistant subjects
V Rotter et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Hypoxia-inducible factor-1 mediates activation of cultured vascular endothelial cells by inducing multiple angiogenic factors
M Yamakawa et al.
CIRCULATION RESEARCH (2003)
Angiogenesis in health and disease
P Carmeliet
NATURE MEDICINE (2003)
Triglyceride accumulation protects against fatty acid-induced lipotoxicity
LL Listenberger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Inflammatory cytokines and the risk to develop type 2 diabetes -: Results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study
J Spranger et al.
DIABETES (2003)
CCAAT/enhancer-binding protein β is required for mitotic clonal expansion during adipogenesis
QQ Tang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Early B-cell factor (O/E-1) is a promoter of adipogenesis and involved in control of genes important for terminal adipocyte differentiation
P Åkerblad et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects
JG Yu et al.
DIABETES (2002)
Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IκB-α
SI Itani et al.
DIABETES (2002)
Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability
I Janssen et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2002)
C/EBPα is required for differentiation of white, but not brown, adipose tissue
HG Linhart et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Elevated C-reactive protein -: Another component of the atherothrombotic profile of abdominal obesity
I Lemieux et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2001)
Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver
ED Abel et al.
NATURE (2001)
Enlarged subcutaneous abdominal adipocyte size, but not obesity itself, predicts Type II diabetes independent of insulin resistance
C Weyer et al.
DIABETOLOGIA (2000)
Lipoatrophy revisited
ML Reitman et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2000)
Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones
L Chao et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes
J Himms-Hagen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2000)
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