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Richard D'Mello et al.
MOLECULAR THERAPY (2011)
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
Christopher J. Bohlen et al.
NATURE (2011)
Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca2+ channel complex
Joel M. Brittain et al.
NATURE MEDICINE (2011)
The Cavβ subunit prevents RFP2-mediated ubiquitination and proteasomal degradation of L-type channels
Christophe Altier et al.
NATURE NEUROSCIENCE (2011)
Transient receptor potential channels as therapeutic targets
Magdalene M. Moran et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
Behavioral analysis of NR2C knockout mouse reveals deficit in acquisition of conditioned fear and working memory
Brandon G. Hillman et al.
NEUROBIOLOGY OF LEARNING AND MEMORY (2011)
Mix and Match: Heterodimers and Opioid Tolerance
Gavril W. Pasternak et al.
NEURON (2011)
TRPM3 Is a Nociceptor Channel Involved in the Detection of Noxious Heat
Joris Vriens et al.
NEURON (2011)
Cav2.3 Channels Are Critical for Oscillatory Burst Discharges in the Reticular Thalamus and Absence Epilepsy
Tariq Zaman et al.
NEURON (2011)
Brain-derived neurotrophic factor from microglia: a molecular substrate for neuropathic pain
Tuan Trang et al.
NEURON GLIA BIOLOGY (2011)
TRPV1, TRPA1, and CB1 in the isolated vagus nerve - Axonal chemosensitivity and control of neuropeptide release
K. Weller et al.
NEUROPEPTIDES (2011)
GABAergic disinhibition induced pain hypersensitivity by upregulating NMDA receptor functions in spinal dorsal horn
Jing Cao et al.
NEUROPHARMACOLOGY (2011)
SELECTIVE KNOCKDOWN OF NMDA RECEPTORS IN PRIMARY AFFERENT NEURONS DECREASES PAIN DURING PHASE 2 OF THE FORMALIN TEST
J. A. McRoberts et al.
NEUROSCIENCE (2011)
PROTEINASE-ACTIVATED RECEPTOR 2 SENSITIZES TRANSIENT RECEPTOR POTENTIAL VANILLOID 1, TRANSIENT RECEPTOR POTENTIAL VANILLOID 4, AND TRANSIENT RECEPTOR POTENTIAL ANKYRIN 1 IN PACLITAXEL-INDUCED NEUROPATHIC PAIN
Y. Chen et al.
NEUROSCIENCE (2011)
Differential gene expression of neonatal and adult DRG neurons correlates with the differential sensitization of TRPV1 responses to nerve growth factor
Weiguo Zhu et al.
NEUROSCIENCE LETTERS (2011)
Induction of the P2X7 receptor in spinal microglia in a neuropathic pain model
Kimiko Kobayashi et al.
NEUROSCIENCE LETTERS (2011)
Synaptic Plasticity and Pain: Role of Ionotropic Glutamate Receptors
Max Larsson et al.
NEUROSCIENTIST (2011)
Mechanistic differentiation of cancer pain: A pivotal role of P2X7 is absent
Iain Chessell et al.
PAIN (2011)
Contribution of afferent pathways to nerve injury-induced spontaneous pain and evoked hypersensitivity
Tamara King et al.
PAIN (2011)
Leptin enhances NMDA-induced spinal excitation in rats: A functional link between adipocytokine and neuropathic pain
Yinghong Tian et al.
PAIN (2011)
A novel slow-inactivation-specific ion channel modulator attenuates neuropathic pain
Michael E. Hildebrand et al.
PAIN (2011)
Calcium channel alpha-2-delta-1 protein upregulation in dorsal spinal cord mediates spinal cord injury-induced neuropathic pain states
Amin Boroujerdi et al.
PAIN (2011)
A novel role for TRPM8 in visceral afferent function
Andrea M. Harrington et al.
PAIN (2011)
Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation
Jun Chen et al.
PAIN (2011)
Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia
Claire Gaveriaux-Ruff et al.
PAIN (2011)
Central sensitization: Implications for the diagnosis and treatment of pain
Clifford J. Woolf
PAIN (2011)
Blockade of Persistent Sodium Currents Contributes to the Riluzole-Induced Inhibition of Spontaneous Activity and Oscillations in Injured DRG Neurons
Rou-Gang Xie et al.
PLOS ONE (2011)
Pharmacological Blockade of TRPM8 Ion Channels Alters Cold and Cold Pain Responses in Mice
Wendy M. Knowlton et al.
PLOS ONE (2011)
Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system
Peter Holzer
PHARMACOLOGY & THERAPEUTICS (2011)
T-type calcium channels contribute to colonic hypersensitivity in a rat model of irritable bowel syndrome
Fabrice Marger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Voltage-Gated Calcium Channels
William A. Catterall
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)
EphrinB2 induces pelvic-urethra reflex potentiation via Src kinase-dependent tyrosine phosphorylation of NR2B
Hsi-Chin Wu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2011)
Mechanism for Noncompetitive Inhibition by Novel GluN2C/D N-Methyl-D-aspartate Receptor Subunit-Selective Modulators
Timothy M. Acker et al.
MOLECULAR PHARMACOLOGY (2011)
TTA-P2 Is a Potent and Selective Blocker of T-Type Calcium Channels in Rat Sensory Neurons and a Novel Antinociceptive Agent
WonJoo Choe et al.
MOLECULAR PHARMACOLOGY (2011)
Transient receptor potential ion channels V4 and A1 contribute to pancreatitis pain in mice
Eugene Ceppa et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)
Transient receptor potential ankyrin-1 has a major role in mediating visceral pain in mice
Fiore Cattaruzza et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)
Time to Onset of Neuropathic Pain Reduction: A Retrospective Analysis of Data From Nine Controlled Trials of Pregabalin for Painful Diabetic Peripheral Neuropathy and Postherpetic Neuralgia
Uma Sharma et al.
AMERICAN JOURNAL OF THERAPEUTICS (2010)
The anti-allodynic α2δ ligand pregabalin inhibits the trafficking of the calcium channel α2δ-1 subunit to presynaptic terminals in vivo
Claudia S. Bauer et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2010)
Structure-activity relationships of diphenylpiperazine N-type calcium channel inhibitors
Hassan Pajouhesh et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Involvement of the spinal NMDA receptor/PKCγ signaling pathway in the development of bone cancer pain
Gu Xiaoping et al.
BRAIN RESEARCH (2010)
A role for transient receptor potential vanilloid 4 in tonicity-induced neurogenic inflammation
N. Vergnolle et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Reversal of acid-induced and inflammatory pain by the selective ASIC3 inhibitor, APETx2
Jerzy Karczewski et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Time course and specificity of the pharmacological disruption of the trafficking of voltage-gated calcium channels by gabapentin
Fay Heblich et al.
Channels (2010)
Splice-variant changes of the CaV3.2 T-type calcium channel mediate voltage-dependent facilitation and associate with cardiac hypertrophy and development
Laurence S. David et al.
CHANNELS (2010)
Acute modulation of calcium currents and synaptic transmission by gabapentinoids
Osvaldo D. Uchitel et al.
CHANNELS (2010)
G protein inhibition of CaV2 calcium channels
Kevin P. M. Currie
CHANNELS (2010)
Analgesic alpha-conotoxins Vc1.1 and RgIA inhibit N-type calcium channels in sensory neurons of alpha 9 nicotinic receptor knockout mice
Brid Callaghan et al.
CHANNELS (2010)
The neuronal splicing factor Nova controls alternative splicing in N-type and P-type CaV2 calcium channels
Summer E. Allen et al.
CHANNELS (2010)
Progress in the structural understanding of voltage-gated calcium channel (CaV) function and modulation
Felix Findeisen et al.
CHANNELS (2010)
Impact of Socioeconomic Status, Race, and Ethnicity on Quality of Life in Patients With Cystic Fibrosis in the United States
Alexandra L. Quittner et al.
CHEST (2010)
CCR2 Antagonists
Mary Struthers et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2010)
P2X4 receptors mediate PGE2 release by tissue-resident macrophages and initiate inflammatory pain
Lauriane Ulmann et al.
EMBO JOURNAL (2010)
Impairment of CaMKII activation and attenuation of neuropathic pain in mice lacking NR2B phosphorylated at Tyr1472
Shinji Matsumura et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2010)
Glutamate receptor phosphorylation and trafficking in pain plasticity in spinal cord dorsal horn
Xue Jun Liu et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2010)
The role of N-methyl-D-aspartate receptor subunit NR2B in spinal cord in cancer pain
XiaoPing Gu et al.
EUROPEAN JOURNAL OF PAIN (2010)
Effect of transient receptor potential vanilloid 1 (TRPV1) receptor antagonist compounds SB705498, BCTC and AMG9810 in rat models of thermal hyperalgesia measured with an increasing-temperature water bath
Valeria Tekus et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2010)
Pre-treatment with capsaicin in a rat osteoarthritis model reduces the symptoms of pain and bone damage induced by monosodium iodoacetate
Karel-Martijn Kalff et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2010)
Contribution of the spinal cord BDNF to the development of neuropathic pain by activation of the NR2B-containing NMDA receptors in rats with spinal nerve ligation
Shan-Jing Geng et al.
EXPERIMENTAL NEUROLOGY (2010)
Transient receptor potential vanilloid-1 antagonists: a survey of recent patent literature
Eric A. Voight et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2010)
The P2X7 purinergic receptor: from physiology to neurological disorders
Stephen D. Skaper et al.
FASEB JOURNAL (2010)
Two haplotypes of the P2X7 receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1β secretion
Leanne Stokes et al.
FASEB JOURNAL (2010)
Cathepsin S Release from Primary Cultured Microglia Is Regulated by the P2X7 Receptor
Anna K. Clark et al.
GLIA (2010)
Expression of the TRPV1 receptor differs in quiescent inflammatory bowel disease with or without abdominal pain
Ayesha Akbar et al.
GUT (2010)
Bisphenol-A can bind to human glucocorticoid receptor as an agonist: an in silico study
G. K. Prasanth et al.
JOURNAL OF APPLIED TOXICOLOGY (2010)
Heterodimerization of ORL1 and Opioid Receptors and Its Consequences for N-type Calcium Channel Regulation
Rhian M. Evans et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
What is this thing called pain?
Clifford J. Woolf
JOURNAL OF CLINICAL INVESTIGATION (2010)
Impaired Glial Glutamate Uptake Induces Extrasynaptic Glutamate Spillover in the Spinal Sensory Synapses of Neuropathic Rats
Hui Nie et al.
JOURNAL OF NEUROPHYSIOLOGY (2010)
P2X7-Dependent Release of Interleukin-1β and Nociception in the Spinal Cord following Lipopolysaccharide
Anna K. Clark et al.
JOURNAL OF NEUROSCIENCE (2010)
Cav3.2 T-Type Ca2+ Channel-Dependent Activation of ERK in Paraventricular Thalamus Modulates Acid-Induced Chronic Muscle Pain
Wen-Kwei Chen et al.
JOURNAL OF NEUROSCIENCE (2010)
Contributions of Different Modes of TRPV1 Activation to TRPV1 Antagonist-Induced Hyperthermia
Andras Garami et al.
JOURNAL OF NEUROSCIENCE (2010)
touche Is Required for Touch-Evoked Generator Potentials within Vertebrate Sensory Neurons
Sean E. Low et al.
JOURNAL OF NEUROSCIENCE (2010)
The α2δ Ligand Gabapentin Inhibits the Rab11-Dependent Recycling of the Calcium Channel Subunit α2δ-2
Alexandra Tran-Van-Minh et al.
JOURNAL OF NEUROSCIENCE (2010)
Synaptic Plasticity and Central Sensitization: Author Reply
Alban Latremoliere et al.
JOURNAL OF PAIN (2010)
Central Sensitization Versus Synaptic Long-Term Potentiation (LIP): A Critical Comment
Juergen Sandkuehler
JOURNAL OF PAIN (2010)
A Randomized, Controlled, Open-Label Study of the Long-Term Effects of NGX-4010, a High-Concentration Capsaicin Patch, on Epidermal Nerve Fiber Density and Sensory Function in Healthy Volunteers
William R. Kennedy et al.
JOURNAL OF PAIN (2010)
ASIC1 and ASIC3 Play Different Roles in the Development of Hyperalgesia After Inflammatory Muscle Injury
Roxanne Y. Walder et al.
JOURNAL OF PAIN (2010)
Analgesic Effects of a Substituted N-Triazole Oxindole (TROX-1), a State-Dependent, Voltage-Gated Calcium Channel 2 Blocker
Catherine Abbadie et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
Identification and Characterization of Novel NMDA Receptor Antagonists Selective for NR2A-over NR2B-Containing Receptors
Ezio Bettini et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
NMDAR-mediated EPSCs are maintained and accelerate in time course during maturation of mouse and rat auditory brainstem in vitro
Joern R. Steinert et al.
JOURNAL OF PHYSIOLOGY-LONDON (2010)
R-type Calcium Channel Isoform in Rat Dorsal Root Ganglion Neurons
Zhi Fang et al.
KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY (2010)
Ziconotide for treatment of severe chronic pain
Achim Schmidtko et al.
LANCET (2010)
NR2 subunits and NMDA receptors on lamina II inhibitory and excitatory interneurons of the mouse dorsal horn
Hiroaki Shiokawa et al.
MOLECULAR PAIN (2010)
Analgesic effect of highly reversible ω-conotoxin FVIA on N type Ca2+ channels
Seungkyu Lee et al.
MOLECULAR PAIN (2010)
Nociceptor-expressed ephrin-B2 regulates inflammatory and neuropathic pain
Jing Zhao et al.
MOLECULAR PAIN (2010)
ASIC3 Channels Integrate Agmatine and Multiple Inflammatory Signals through the Nonproton Ligand Sensing Domain
Wei-Guang Li et al.
MOLECULAR PAIN (2010)
TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats
Steve McGaraughty et al.
MOLECULAR PAIN (2010)
Analgesic ω-Conotoxins CVIE and CVIF Selectively and Voltage-Dependently Block Recombinant and Native N-Type Calcium Channels
G. Berecki et al.
MOLECULAR PHARMACOLOGY (2010)
CCR2 Receptor Ligands Inhibit Cav3.2 T-Type Calcium Channels
Haitao You et al.
MOLECULAR PHARMACOLOGY (2010)
Central mechanisms of pathological pain
Rohini Kuner
NATURE MEDICINE (2010)
Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions
Zhen-Zhong Xu et al.
NATURE MEDICINE (2010)
Regulation of neuronal activity by Cav3-Kv4 channel signaling complexes
Dustin Anderson et al.
NATURE NEUROSCIENCE (2010)
Opioid inhibition of N-type Ca2+ channels and spinal analgesia couple to alternative splicing
Arturo Andrade et al.
NATURE NEUROSCIENCE (2010)
Observational fear learning involves affective pain system and Cav1.2 Ca2+ channels in ACC
Daejong Jeon et al.
NATURE NEUROSCIENCE (2010)
Neuronal circuitry for pain processing in the dorsal horn
Andrew J. Todd
NATURE REVIEWS NEUROSCIENCE (2010)
Effects of capsaicin-containing red pepper sauce suspension on esophageal secondary peristalsis in humans
C. L. Chen et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2010)
R-type Ca2+ channels contribute to fast synaptic excitation and action potentials in subsets of myenteric neurons in the guinea pig intestine
V. Naidoo et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2010)
A Nonproton Ligand Sensor in the Acid-Sensing Ion Channel
Ye Yu et al.
NEURON (2010)
Ion Channel Voltage Sensors: Structure, Function, and Pathophysiology
William A. Catterall
NEURON (2010)
A Gain-of-Function Mutation in TRPA1 Causes Familial Episodic Pain Syndrome
Barbara Kremeyer et al.
NEURON (2010)
MORPHINE TOLERANCE ATTENUATES THE RESOLUTION OF POSTOPERATIVE PAIN AND ENHANCES SPINAL MICROGLIAL p38 AND EXTRACELLULAR RECEPTOR KINASE PHOSPHORYLATION
R. J. Horvath et al.
NEUROSCIENCE (2010)
NMDA RECEPTORS IN PRIMARY AFFERENTS REQUIRE PHOSPHORYLATION BY Src FAMILY KINASES TO INDUCE SUBSTANCE P RELEASE IN THE RAT SPINAL CORD
W. Chen et al.
NEUROSCIENCE (2010)
Microneurography: An opportunity for translational drug development in neuropathic pain Introduction
Jordi Serra
NEUROSCIENCE LETTERS (2010)
The beta Subunit of Voltage-Gated Ca2+ Channels
Zafir Buraei et al.
PHYSIOLOGICAL REVIEWS (2010)
Paradoxical effects of the cannabinoid CB2 receptor agonist GW405833 on rat osteoarthritic knee joint pain
N. Schuelert et al.
OSTEOARTHRITIS AND CARTILAGE (2010)
A-995662 [(R)-8-(4-methyl-5-(4-(trifluoromethyl)phenyl)oxazol-2-ylamino)-1,2,3,4-tetrahydronaphthalen-2-ol], a novel, selective TRPV1 receptor antagonist, reduces spinal release of glutamate and CGRP in a rat knee joint pain model
Pamela S. Puttfarcken et al.
PAIN (2010)
Loose ligation of the rat sciatic nerve elicits early accumulation of Shank1 protein in the post-synaptic density of spinal dorsal horn neurons
Gordana Miletic et al.
PAIN (2010)
TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo
Wendy M. Knowlton et al.
PAIN (2010)
Neonatal colon insult alters growth factor expression and TRPA1 responses in adult mice
Julie A. Christianson et al.
PAIN (2010)
NMDA Receptor Antagonists for the Treatment of Neuropathic Pain
Susan Collins et al.
PAIN MEDICINE (2010)
Role of voltage-gated calcium channels in epilepsy
Gerald W. Zamponi et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2010)
Transient receptor potential channelopathies
Bernd Nilius et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2010)
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
Stephen F. Traynelis et al.
PHARMACOLOGICAL REVIEWS (2010)
The Roles of T-Type Calcium Channel in the Development of Neuropathic Pain following Chronic Compression of Rat Dorsal Root Ganglia
Xian-Jie Wen et al.
PHARMACOLOGY (2010)
The paradoxical role of the transient receptor potential vanilloid 1 receptor in inflammation
Khadija Alawi et al.
PHARMACOLOGY & THERAPEUTICS (2010)
The α2δ subunits of voltage-gated calcium channels form GPI-anchored proteins, a posttranslational modification essential for function
Anthony Davies et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Increased Abundance of Opioid Receptor Heteromers After Chronic Morphine Administration
Achla Gupta et al.
SCIENCE SIGNALING (2010)
GABAB receptor activation exacerbates spontaneous spike-and-wave discharges in DBA/2J mice
Marco Bortolato et al.
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY (2010)
The Role of Transient Receptor Potential Cation Channels in Ca2+ Signaling
Maarten Gees et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
A subunit-selective potentiator of NR2C-and NR2D-containing NMDA receptors
Praseeda Mullasseril et al.
NATURE COMMUNICATIONS (2010)
A Post-Burst Afterdepolarization Is Mediated by Group I Metabotropic Glutamate Receptor-Dependent Upregulation of Cav2.3 R-Type Calcium Channels in CA1 Pyramidal Neurons
Jin-Yong Park et al.
PLOS BIOLOGY (2010)
Heteromerization of TRP channel subunits: extending functional diversity
Wei Cheng et al.
PROTEIN & CELL (2010)
Endogenous ephrinB2 mediates colon-urethra cross-organ sensitization via Src kinase-dependent tyrosine phosphorylation of NR2B
Hsien-Yu Peng et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2010)
TRPA1 in mast cell activation-induced long-lasting mechanical hypersensitivity of vagal afferent C-fibers in guinea pig esophagus
Shaoyong Yu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2009)
Ifenprodil Induced Antinociception and Decreased the Expression of NR2B Subunits in the Dorsal Horn After Chronic Dorsal Root Ganglia Compression in Rats
Wei Zhang et al.
ANESTHESIA AND ANALGESIA (2009)
Attenuation of Mechanical Hypersensitivity by an Antagonist of the TRPA1 Ion Channel in Diabetic Animals
Hong Wei et al.
ANESTHESIOLOGY (2009)
Signaling at Purinergic P2X Receptors
Annmarie Surprenant et al.
ANNUAL REVIEW OF PHYSIOLOGY (2009)
The antihyperalgesic activity of a selective P2X7 receptor antagonist, A-839977, is lost in IL-1αβ knockout mice
Prisca Honore et al.
BEHAVIOURAL BRAIN RESEARCH (2009)
Regulation of T-type calcium channels: Signalling pathways and functional implications
Sylvaine Huc et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
Suppression of Formalin-Induced Nociception by Cilnidipine, a Voltage-Dependent Calcium Channel Blocker
Hajime Koganei et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2009)
Identification and SAR of novel diaminopyrimidines. Part 1: The discovery of RO-4, a dual P2X3/P2X2/3 antagonist for the treatment of pain
David S. Carter et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Scaffold-based design and synthesis of potent N-type calcium channel blockers
Gerald W. Zamponi et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Differential expression of L- and N-type voltage-sensitive calcium channels in the spinal cord of morphine plus nimodipine treated rats
Dilip Verma et al.
BRAIN RESEARCH (2009)
Development, plasticity and modulation of visceral afferents
Julie A. Christianson et al.
BRAIN RESEARCH REVIEWS (2009)
Therapeutic potential of vanilloid receptor TRPV1 agonists and antagonists as analgesics: Recent advances and setbacks
Gilbert Y. Wong et al.
BRAIN RESEARCH REVIEWS (2009)
Chemokines and pain mechanisms
Catherine Abbadie et al.
BRAIN RESEARCH REVIEWS (2009)
Disruption of nNOS-PSD95 protein-protein interaction inhibits acute thermal hyperalgesia and chronic mechanical allodynia in rodents
S. K. Florio et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis
Cagla Eroglu et al.
CELL (2009)
Dissociation of the Opioid Receptor Mechanisms that Control Mechanical and Heat Pain
Gregory Scherrer et al.
CELL (2009)
Cellular and Molecular Mechanisms of Pain
Allan I. Basbaum et al.
CELL (2009)
Effects of neuropathy on high-voltage-activated Ca2+ current in sensory neurones
Li Yang et al.
CELL CALCIUM (2009)
Native and recombinant ASIC1a receptors conduct negligible Ca2+ entry
Damien S. K. Samways et al.
CELL CALCIUM (2009)
Kelch-like 1 protein upregulates T-type currents by an actin-F dependent increase in α1H channels via the recycling endosome
K. A. Aromolaran et al.
CHANNELS (2009)
TRP Channels and Pain
Daniel N. Cortright et al.
CURRENT PHARMACEUTICAL DESIGN (2009)
Selective T-Type Calcium Channel Blockade Alleviates Hyperalgesia in ob/ob Mice
Janelle R. Latham et al.
DIABETES (2009)
Spinal NK-1 receptor-expressing neurons and descending pathways support fentanyl-induced pain hypersensitivity in a rat model of postoperative pain
Cyril Rivat et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2009)
Acid increases inflammatory pain in rats: Effect of local peripheral ASICs inhibitors
Hector I. Rocha-Gonzalez et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Role of the spinal cord NR2B-containing NMDA receptors in the development of neuropathic pain
Xiao-Xiu Qu et al.
EXPERIMENTAL NEUROLOGY (2009)
The Ion Channel TRPA1 Is Required for Normal Mechanosensation and Is Modulated by Algesic Stimuli
Stuart M. Brierley et al.
GASTROENTEROLOGY (2009)
Transient receptor potential A1 mediates gastric distention-induced visceral pain in rats
T. Kondo et al.
GUT (2009)
Tyrosine Phosphorylation Modulates the Activity of TRPV4 in Response to Defined Stimuli
Tomasz Wegierski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The Cytoskeletal Protein α-Actinin Regulates Acid-sensing Ion Channel 1a through a C-terminal Interaction
Mikael K. Schnizler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Structural Elements for the Generation of Sustained Currents by the Acid Pain Sensor ASIC3
Miguel Salinas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
An Atypical Role for Collapsin Response Mediator Protein 2 (CRMP-2) in Neurotransmitter Release via Interaction with Presynaptic Voltage-gated Calcium Channels
Joel M. Brittain et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Regulation of N-type voltage-gated calcium channels (Cav2.2) and transmitter release by collapsin response mediator protein-2 (CRMP-2) in sensory neurons
Xian Xuan Chi et al.
JOURNAL OF CELL SCIENCE (2009)
Mechanisms underlying fibronectin-induced up-regulation of P2X(4)R expression in microglia: distinct roles of PI3K-Akt and MEK-ERK signalling pathways
Makoto Tsuda et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)
Involvement of R-Type Ca2+ Channels in Neurotransmitter Release From Spinal Dorsolateral Funiculus Terminals Synapsing Motoneurons
Alberto Castro et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2009)
Polymodal Ligand Sensitivity of TRPA1 and Its Modes of Interactions
Sangsu Bang et al.
JOURNAL OF GENERAL PHYSIOLOGY (2009)
Antagonists of the P2X7 Receptor. From Lead Identification to Drug Development
Simon D. Guile et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Alternative Splicing in the Synaptic Protein Interaction Site of Rat Cav2.2 (α1B) Calcium Channels: Changes Induced by Chronic Inflammatory Pain
Sareh Asadi et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2009)
A functional link between T-type calcium channels and μ-opioid receptor expression in adult primary sensory neurons
Zi-Zhen Wu et al.
JOURNAL OF NEUROCHEMISTRY (2009)
TPRV1 Expression Defines Functionally Distinct Pelvic Colon Afferents
Sacha A. Malin et al.
JOURNAL OF NEUROSCIENCE (2009)
T-Type Calcium Channel Inhibition Underlies the Analgesic Effects of the Endogenous Lipoamino Acids
Guillaume Barbara et al.
JOURNAL OF NEUROSCIENCE (2009)
The Increased Trafficking of the Calcium Channel Subunit α2δ-1 to Presynaptic Terminals in Neuropathic Pain Is Inhibited by the α2δ Ligand Pregabalin
Claudia S. Bauer et al.
JOURNAL OF NEUROSCIENCE (2009)
Morphine Enhances Microglial Migration through Modulation of P2X4 Receptor Signaling
Ryan J. Horvath et al.
JOURNAL OF NEUROSCIENCE (2009)
P2X4-Receptor-Mediated Synthesis and Release of Brain-Derived Neurotrophic Factor in Microglia Is Dependent on Calcium and p38-Mitogen-Activated Protein Kinase Activation
Tuan Trang et al.
JOURNAL OF NEUROSCIENCE (2009)
Acid-Sensing Ion Channel 3 Expression in Mouse Knee Joint Afferents and Effects of Carrageenan-Induced Arthritis
Masahiko Ikeuchi et al.
JOURNAL OF PAIN (2009)
Comparison of Oxaliplatin- and Cisplatin-Induced Painful Peripheral Neuropathy in the Rat
Elizabeth K. Joseph et al.
JOURNAL OF PAIN (2009)
Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity
Alban Latremoliere et al.
JOURNAL OF PAIN (2009)
Brain-derived neurotrophic factor drives the changes in excitatory synaptic transmission in the rat superficial dorsal horn that follow sciatic nerve injury
Van B. Lu et al.
JOURNAL OF PHYSIOLOGY-LONDON (2009)
NGX-4010, a high concentration capsaicin patch, for the treatment of postherpetic neuralgia: a randomised, double-blind study (vol 7, pg 1106, 2008)
M. Backonja et al.
LANCET NEUROLOGY (2009)
Mice with cisplatin and oxaliplatin-induced painful neuropathy develop distinct early responses to thermal stimuli
Lauren E. Ta et al.
MOLECULAR PAIN (2009)
An in vivo mouse model of long-term potentiation at synapses between primary afferent C-fibers and spinal dorsal horn neurons: essential role of EphB1 receptor
Wen-Tao Liu et al.
MOLECULAR PAIN (2009)
Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays
Makoto Tsuda et al.
MOLECULAR PAIN (2009)
Pore architecture and ion sites in acid-sensing ion channels and P2X receptors
Eric B. Gonzales et al.
NATURE (2009)
Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors
Rebecca P. Seal et al.
NATURE (2009)
Crystal structure of the ATP-gated P2X4 ion channel in the closed state
Toshimitsu Kawate et al.
NATURE (2009)
Phenotyping sensory nerve endings in vitro in the mouse
Katharina Zimmermann et al.
NATURE PROTOCOLS (2009)
Transient receptor potential channels: targeting pain at the source
Ardem Patapoutian et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Possible role for TRPV1 in neomycin-induced inhibition of visceral hypersensitivity in rat
R. M. van den Wijngaard et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2009)
Neurochemical and morphological phenotypes of vagal afferent neurons innervating the adult mouse jejunum
L. L. Tan et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2009)
Influence of intra-oesophageal capsaicin instillation on heartburn induction and oesophageal sensitivity in man
S. Kindt et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2009)
Nociceptive Signals Induce Trafficking of TRPA1 to the Plasma Membrane
Manuela Schmidt et al.
NEURON (2009)
Synaptic AMPA Receptor Plasticity and Behavior
Helmut W. Kessels et al.
NEURON (2009)
ATP-gated P2X cation-channels
Michael F. Jarvis et al.
NEUROPHARMACOLOGY (2009)
HYPOALGESIC BEHAVIORS OF P/Q-TYPE VOLTAGE-GATED Ca2+ CHANNEL MUTANT MOUSE, ROLLING MOUSE NAGOYA
N. Fukumoto et al.
NEUROSCIENCE (2009)
PURINERGIC RECEPTOR IMMUNOREACTIVITY IN THE ROSTRAL VENTROMEDIAL MEDULLA
L. N. Close et al.
NEUROSCIENCE (2009)
Targeting the NMDA Receptor Subunit NR2B for the Treatment of Neuropathic Pain
Long-Jun Wu et al.
NEUROTHERAPEUTICS (2009)
Repeated dosing of ABT-102, a potent and selective TRPV1 antagonist, enhances TRPV1-mediated analgesic activity in rodents, but attenuates antagonist-induced hyperthermia
Prisca Honore et al.
PAIN (2009)
In vivo silencing of the CaV3.2 T-type calcium channels in sensory neurons alleviates hyperalgesia in rats with streptozocin-induced diabetic neuropathy
Richard B. Messinger et al.
PAIN (2009)
Peripheral inflammation increased the synaptic expression of NMDA receptors in spinal dorsal horn
Xian Yang et al.
PAIN (2009)
N-Methyl-d-aspartate receptor (NMDAR) independent maintenance of inflammatory pain
Amanda R. Weyerbacher et al.
PAIN (2009)
Determinants of the voltage dependence of G protein modulation within calcium channel β subunits
Andriy V. Dresviannikov et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2009)
Regulation of the murine TRPP3 channel by voltage, pH, and changes in cell volume
Takahiro Shimizu et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2009)
IFN-γ receptor signaling mediates spinal microglia activation driving neuropathic pain
Makoto Tsuda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Genetics of the P2X7 receptor and human disease
Stephen J. Fuller et al.
PURINERGIC SIGNALLING (2009)
Congenital insensitivity to pain
N. Danziger et al.
REVUE NEUROLOGIQUE (2009)
Neurotransmitters Drive Combinatorial Multistate Postsynaptic Density Networks
Marcelo P. Coba et al.
SCIENCE SIGNALING (2009)
TRPV1 antagonists: the challenges for therapeutic targeting
Neelima Khairatkar-Joshi et al.
TRENDS IN MOLECULAR MEDICINE (2009)
Regulation of neuronal T-type calcium channels
Mircea C. Iftinca et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2009)
Intrathecal Ziconotide for Neuropathic Pain: A Review
Richard L. Rauck et al.
PAIN PRACTICE (2009)
P2X7 receptor-Pannexin1 complex:: pharmacology and signaling
R. Iglesias et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2008)
Enhanced muscle fatigue occurs in male but not female ASIC3-/- mice
Lynn A. Burnes et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2008)
Modulators of calcium influx regulate membrane excitability in rat dorsal root ganglion neurons
Philipp Lirk et al.
ANESTHESIA AND ANALGESIA (2008)
Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: a molecular mechanism of inflammatory pain
Shenglan Wang et al.
BRAIN (2008)
Comparison of icilin- and cold-evoked responses of spinal neurones, and their modulation of mechanical activity, in a model of neuropathic pain
Jennifer L. Brignell et al.
BRAIN RESEARCH (2008)
The ORL-1 Receptor System: Are There Opportunities for Antagonists in Pain Therapy?
Beatriz Fioravanti et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2008)
ASIC3, a sensor of acidic and primary inflammatory pain
Emmanuel Deval et al.
EMBO JOURNAL (2008)
Formation of a new receptor-operated channel by heteromeric assembly of TRPP2 and TRPC1 subunits
Chang-Xi Bai et al.
EMBO REPORTS (2008)
Regulation of ASIC activity by ASIC4 - new insights into ASIC channel function revealed by a yeast two-hybrid assay
Emmanuelle Donier et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2008)
Viscero-somatic reflexes in referred pain areas evoked by capsaicin stimulation of the human gut
Lars Arendt-Nielsen et al.
EUROPEAN JOURNAL OF PAIN (2008)
Intrathecal antinociceptive interaction between the NMDA antagonist ketamine and the opioids, morphine and biphalin
Dariusz Kosson et al.
EUROPEAN JOURNAL OF PAIN (2008)
Inflammation causes expression of NGF in epithelial cells of the rat colon
Roger D. P. Stanzel et al.
EXPERIMENTAL NEUROLOGY (2008)
Expression, transport, and axonal sorting of neuronal CCL21 in large dense-core vesicles
Eiko K. de Jong et al.
FASEB JOURNAL (2008)
Transient receptor potential vanilloid-4 has a major role in visceral hypersensitivity symptoms
Nicolas Cenac et al.
GASTROENTEROLOGY (2008)
Selective role for TRPV4 ion channels in visceral sensory pathways
Stuart M. Brierley et al.
GASTROENTEROLOGY (2008)
Fibronectin/integrin system is involved in P2X4 receptor upregulation in the spinal cord and neuropathic pain after nerve injury
Makoto Tsuda et al.
GLIA (2008)
P2X7 receptor stimulation in primary cultures of rat spinal microglia induces downregulation of the activity for glutamate transport
Norimitsu Morioka et al.
GLIA (2008)
Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain
A. Akbar et al.
GUT (2008)
CaV3.2 T-type calcium channels are involved in calcium-dependent secretion of neuroendocrine prostate cancer cells
Florian Gackiere et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Upregulation of the T-type calcium current in small rat sensory neurons after chronic constrictive injury of the sciatic nerve
Miljen M. Jagodic et al.
JOURNAL OF NEUROPHYSIOLOGY (2008)
Bradykinin enhances AMPA and NMDA receptor activity in spinal cord dorsal horn neurons by activating multiple kinases to produce pain hypersensitivity
Tatsuro Kohno et al.
JOURNAL OF NEUROSCIENCE (2008)
Mechanisms of compartmentalized expression of Mrg class G-protein-coupled sensory receptors
Yang Liu et al.
JOURNAL OF NEUROSCIENCE (2008)
Analgesic α-Conotoxins Vc1.1 and Rg1A Inhibit N-Type Calcium Channels in Rat Sensory Neurons via GABAB Receptor Activation
Brid Callaghan et al.
JOURNAL OF NEUROSCIENCE (2008)
Visualizing cold spots: TRPM8-expressing sensory neurons and their projections
Ajay Dhaka et al.
JOURNAL OF NEUROSCIENCE (2008)
Overexpressed Transient Receptor Potential Vanilloid 3 Ion Channels in Skin Keratinocytes Modulate Pain Sensitivity via Prostaglandin E2
Susan M. Huang et al.
JOURNAL OF NEUROSCIENCE (2008)
Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress
David A. Andersson et al.
JOURNAL OF NEUROSCIENCE (2008)
Interaction of transient receptor potential vanilloid 4, integrin, and Src tyrosine kinase in mechanical hyperalgesia
Nicole Alessandri-Haber et al.
JOURNAL OF NEUROSCIENCE (2008)
Acid sensing ion channels in dorsal spinal cord neurons
Anne Baron et al.
JOURNAL OF NEUROSCIENCE (2008)
Cytokine mechanisms of central sensitization:: Distinct and overlapping role of interleukin-1β, interleukin-6, and tumor necrosis factor-β in regulating synaptic and neuronal activity in the superficial spinal cord
Yasuhiko Kawasaki et al.
JOURNAL OF NEUROSCIENCE (2008)
Phosphoinositides Regulate P2X4 ATP-Gated Channels through Direct Interactions
Louis-Philippe Bernier et al.
JOURNAL OF NEUROSCIENCE (2008)
Up-Regulation of P2X4 Receptors in Spinal Microglia after Peripheral Nerve Injury Mediates BDNF Release and Neuropathic Pain
Lauriane Ulmann et al.
JOURNAL OF NEUROSCIENCE (2008)
Spinal Dynorphin and Bradykinin Receptors Maintain Inflammatory Hyperalgesia
Miaw-Chyi Luo et al.
JOURNAL OF PAIN (2008)
σ-1 Receptor Modulation of Acid-Sensing Ion Channel a (ASIC1a) and ASIC1a-Induced Ca2+ Influx in Rat Cortical Neurons
Yelenis Herrera et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
Switch to Ca2+-permeable AMPA and reduced NR2B NMDA receptor-mediated neurotransmission at dorsal horn nociceptive synapses during inflammatory pain in the rat
Kristina S. Vikman et al.
JOURNAL OF PHYSIOLOGY-LONDON (2008)
Functional contributions of synaptically localized NR2B subunits of the NMDA receptor to synaptic transmission and long-term potentiation in the adult mouse CNS
Hideki Miwa et al.
JOURNAL OF PHYSIOLOGY-LONDON (2008)
NR2B- and NR2D-containing synaptic NMDA receptors in developing rat substantia nigra pars compacta dopaminergic neurones
S. L. C. Brothwell et al.
JOURNAL OF PHYSIOLOGY-LONDON (2008)
Signaling complexes of voltage-gated calcium channels and G protein-coupled receptors
Christophe Altier et al.
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2008)
Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice
Thomas Christoph et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2008)
NMDA receptors in clinical neurology: excitatory times ahead
Lorraine V. Kalia et al.
LANCET NEUROLOGY (2008)
Distinct expression of synaptic NR2A and NR2B in the central nervous system and impaired morphine tolerance and physical dependence in mice deficient in postsynaptic density-93 protein
Wen-Jinn Liaw et al.
MOLECULAR PAIN (2008)
Functional identification of NR2 subunits contributing to NMDA receptors on substance P receptor-expressing dorsal horn neurons
Chi-Kun Tong et al.
MOLECULAR PAIN (2008)
HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity
Samer R. Eid et al.
MOLECULAR PAIN (2008)
Cell-permeable Peptide Tat-PSD-95 PDZ2 Inhibits Chronic Inflammatory Pain Behaviors in Mice
Feng Tao et al.
MOLECULAR THERAPY (2008)
Repeated electro-acupuncture attenuates chronic visceral hypersensitivity and spinal cord NMDA receptor phosphorylation in a rat irritable bowel syndrome model
Shun-Lian Tian et al.
LIFE SCIENCES (2008)
Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex
Xue Jun Liu et al.
NATURE MEDICINE (2008)
Controlled trial of high-concentration capsaicin patch for treatment of painful HIV neuropathy
David M. Simpson et al.
NEUROLOGY (2008)
An open-label, multicenter study of the safety and efficacy of intrathecal ziconotide for severe chronic pain when delivered via an external pump
Ann Ver Donck et al.
NEUROMODULATION (2008)
Proinflammatory mediators modulate the heat-activated ion channel TRPV1 via the scaffolding protein AKAP79/150
Xuming Zhang et al.
NEURON (2008)
D1 receptors physically interact with N-type calcium channels to regulate channel distribution and dendritic calcium entry
Alexandra E. Kisilevsky et al.
NEURON (2008)
Multiple roles of calcium ions in the regulation of neurotransmitter release
Erwin Neher et al.
NEURON (2008)
Inflammatory pain-induced signaling events following a conditional deletion of the N-methyl-D-aspartate receptor in spinal cord dorsal horn
H. T. Cheng et al.
NEUROSCIENCE (2008)
Anatomical localization and expression pattern for the NMDA-2D receptor subunit in a rat model of neuropathic pain
M. Hummel et al.
NEUROSCIENCE (2008)
EphrinB2 induces tyrosine phosphorylation of NR2B via Src-family kinases during inflammatory hyperalgesia
S. Slack et al.
NEUROSCIENCE (2008)
Interleukin 1β facilitates bone cancer pain in rats by enhancing NMDA receptor NR-1 subunit phosphorylation
R. -X. Zhang et al.
NEUROSCIENCE (2008)
Distinct chemical classes of medium-sized transient receptor potential channel vanilloid 1-immunoreactive dorsal root ganglion neurons innervate the adult mouse jejunum and colon
L. L. Tan et al.
NEUROSCIENCE (2008)
TRPA1 receptor localisation in the human peripheral nervous system and functional studies in cultured human and rat sensory neurons
U. Anand et al.
NEUROSCIENCE LETTERS (2008)
Compensatory increase in P/Q-calcium current-mediated synaptic transmission following chronic block of N-type channels
Christiane Grimm et al.
NEUROSCIENCE LETTERS (2008)
Transient receptor potential ankyrin-1 participates in visceral hyperalgesia following experimental colitis
Jing Yang et al.
NEUROSCIENCE LETTERS (2008)
Activity-dependent potentiation of calcium signals in spinal sensory networks in inflammatory pain states
Ceng Luo et al.
PAIN (2008)
Estrogen alters spinal NMDA receptor activity via a PKA signaling pathway in a visceral pain model in the rat
Bin Tang et al.
PAIN (2008)
EphrinB-EphB receptor signaling contributes to neuropathic pain by regulating neural excitability and spinal synaptic plasticity in rats
Xue-Ju Song et al.
PAIN (2008)
IL-1ra alleviates inflammatory hyperalgesia through preventing phosphorylation of NMDA receptor NR-1 subunit in rats
Rui-Xin Zhang et al.
PAIN (2008)
Role of ASIC3 in the primary and secondary hyperalgesia produced by joint inflammation in mice
M. Ikeuchi et al.
PAIN (2008)
Injury discharges regulate calcium channel alpha-2-delta-1 subunit upregulation in the dorsal horn that contributes to initiation of neuropathic pain
Amin Boroujerdi et al.
PAIN (2008)
Activation of P2X7 receptors in glial satellite cells reduces pain through downregulation of P2X3 receptors in nociceptive neurons
Yong Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Acid-sensing ion channels interact with and inhibit BKK+ channels
Elena Yerimolaieva Petroff et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Pharmacological disruption of calcium channel trafficking by the α2δ ligand gabapentin
Jan Hendrich et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Neuronal TRP channels: thermometers, pathfinders and life-savers
Karel Talavera et al.
TRENDS IN NEUROSCIENCES (2008)
NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia: a randomised, double-blind study
Miroslav Backonja et al.
LANCET NEUROLOGY (2008)
Are α9α10 nicotinic acetylcholine receptors a pain target for α-conotoxins?
S. T. Nevin et al.
MOLECULAR PHARMACOLOGY (2007)
Regulation of P2X4 receptors by lysosomal targeting, glycan protection and exocytosis
Omar S. Qureshi et al.
JOURNAL OF CELL SCIENCE (2007)
Extrasynaptic and synaptic and uniform pools in rat hi NMDA receptors form stable ppocampal slices
Alexander Z. Harris et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
Upregulation of acid-sensing ion channel ASIC1a in spinal dorsal horn neurons contributes to inflammatory pain hypersensitivity
Bo Duan et al.
JOURNAL OF NEUROSCIENCE (2007)
Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers
Alexander M. Binshtok et al.
NATURE (2007)
Pharmacological comparison of anticonvulsant drugs in animal models of persistent pain and anxiety
Gordon Munro et al.
NEUROPHARMACOLOGY (2007)
Transformation of the output of spinal lamina I neurons after nerve injury and microglia stimulation underlying neuropathic pain
A. Florence Keller et al.
MOLECULAR PAIN (2007)
Structure of acid-sensing ion channel 1 at 1.9A resolution and low pH
Jayasankar Jasti et al.
NATURE (2007)
Design and evaluation of small interfering RNAs that target expression of the N-methyl-D-aspartate receptor NR1 subunit gene in the spinal cord dorsal horn
Sandra M. Garraway et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
TRPA1 mediates formalin-induced pain
Colleen R. McNamara et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
Marcello Trevisani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
A tarantula peptide against pain via ASIC1a channels and opioid mechanisms
Michel Mazzuca et al.
NATURE NEUROSCIENCE (2007)
The menthol receptor TRPM8 is the principal detector of environmental cold
Diana M. Bautista et al.
NATURE (2007)
Regulation of T-type calcium channels by Rho-associated kinase
Mircea Iftinca et al.
NATURE NEUROSCIENCE (2007)
Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain
Yi Dai et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Attenuated pain responses in mice lacking CaV3.2 T-type channels
S. Choi et al.
GENES BRAIN AND BEHAVIOR (2007)
Short-term sensitization of colon mechano receptors is associated with long-term hypersensitivity to colon distention in the mouse
R. Carter et al.
GASTROENTEROLOGY (2007)
The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity
Polina V. Lishko et al.
NEURON (2007)
Differential role of N-type calcium channel splice isoforms in pain
Christophe Altier et al.
JOURNAL OF NEUROSCIENCE (2007)
Purinergic actions on neurons that modulate nociception in the rostral ventromedial medulla
N. R. Selden et al.
NEUROSCIENCE (2007)
A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons
Wenqin Luo et al.
NEURON (2007)
Pain facilitation and activity-dependent plasticity in pain modulatory circuitry: Role of BDNF-TrkB signaling and NMDA receptors
Ke Ren et al.
MOLECULAR NEUROBIOLOGY (2007)
The Cav2.3 calcium channel antagonist SNX-482 reduces dorsal horn neuronal responses in a rat model of chronic neuropathic pain
Elizabeth A. Matthews et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2007)
Ca2+ channel α2-δ ligands for the treatment of neuropathic pain
Mark J. Field et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
Behavioral and immunohistological assessment of painful neuropathy induced by a single oxaliplatin injection in the rat
Bing Ling et al.
TOXICOLOGY (2007)
Sex-related differences in NMDA-evoked rat masseter muscle afferent discharge result from estrogen-mediated modulation of peripheral NMDA receptor activity
X-D. Dong et al.
NEUROSCIENCE (2007)
Attenuated cold sensitivity in TRPM8 null mice
Raymond W. Colburn et al.
NEURON (2007)
Spinal NK-1 receptor expressing neurons mediate opioid-induced hyperalgesia and antinociceptive tolerance via activation of descending pathways
Louis P. Vera-Portocarrero et al.
PAIN (2007)
Differential involvement of TRPV1 receptors at the central and peripheral nerves in CFA-induced mechanical and thermal hyperalgesia
Yoshihito Kanai et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2007)
Functional biology of the α2δ subunits of voltage-gated calcium channels
Anthony Davies et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2007)
Activation of TRPA1 channel facilitates excitatory synaptic transmission in substantia gelatinosa neurons of the adult rat spinal cord
Masafumi Kosugi et al.
JOURNAL OF NEUROSCIENCE (2007)
Characterization of sensations induced by capsaicin in the upper gastrointestinal tract
J. Hammer et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2007)
The vanilloid receptor TRPV1 is tonically activated in vivo and involved in body temperature regulation
Narender R. Gavva et al.
JOURNAL OF NEUROSCIENCE (2007)
Cell-specific alterations of T-type calcium current in painful diabetic neuropathy enhance excitability of sensory neurons
Miljen M. Jagodic et al.
JOURNAL OF NEUROSCIENCE (2007)
NMDA receptor 2B subunit-mediated synaptic transmission in the superficial dorsal horn of peripheral nerve-injured neuropathic mice
Hideaki Iwata et al.
BRAIN RESEARCH (2007)
Thermosensitive TRPV channel subunits coassemble into heteromeric channels with intermediate conductance and gating properties
Wei Cheng et al.
JOURNAL OF GENERAL PHYSIOLOGY (2007)
Alternative splicing controls G protein-dependent inhibition of N-type calcium channels in nociceptors
Jesica Raingo et al.
NATURE NEUROSCIENCE (2007)
Direct activation of the ion channel TRPA1 by Ca2+
Sandra Zurborg et al.
NATURE NEUROSCIENCE (2007)
Molecular basis of CaV2.3 calcium channels in rat nociceptive neurons
Zhi Fang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Localization and comparative analysis of acid-sensing ion channel (ASIC1, 2, and 3) mRNA expression in mouse colonic sensory neurons within thoracolumbar dorsal root ganglia
Patrick A. Hughes et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2007)
Assembly domains in TRP channels
R. Schindl et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
Specification and connectivity of neuronal subtypes in the sensory lineage
Frederic Marmigere et al.
NATURE REVIEWS NEUROSCIENCE (2007)
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
Lindsey J. Macpherson et al.
NATURE (2007)
Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice
Andrew D. Grant et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
Effects of intrathecal injection of T-type calcium channel blockers in the rat formalin test
Jen-Kun Cheng et al.
BEHAVIOURAL PHARMACOLOGY (2007)
A stomatin-domain protein essential for touch sensation in the mouse
Christiane Wetzel et al.
NATURE (2007)
Regulation of NMDA receptors by phosphorylation
Bo-Shiun Chen et al.
NEUROPHARMACOLOGY (2007)
omega-Conotoxin CVIB differentially inhibits native and recombinant N- and P/Q-type calcium channels
Leonid Motin et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2007)
Moving from an averaged to specific view of spinal cord pain processing circuits
B. A. Graham et al.
JOURNAL OF NEUROPHYSIOLOGY (2007)
Transient receptor potential cation channels in disease
Bernd Nilius et al.
PHYSIOLOGICAL REVIEWS (2007)
Physiology and pathophysiology of purinergic neurotransmission
Geoffrey Burnstock
PHYSIOLOGICAL REVIEWS (2007)
The role of P2X(7) in pain and inflammation
Jane P. Hughes et al.
PURINERGIC SIGNALLING (2007)
Timeline - Ideas about pain, a historical view
Edward R. Perl
NATURE REVIEWS NEUROSCIENCE (2007)
Investigation into the role of P2X3/P2X2/3 receptors in neuropathic pain following chronic constriction injury in the rat:: an electrophysiological study
Caroline J. Sharp et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
An SCN9A channelopathy causes congenital inability to experience pain
James J. Cox et al.
NATURE (2006)
The Role of T-Type Calcium Channels in Peripheral and Central Pain Processing
Slobodan M. Todorovic et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2006)
Direct G protein modulation of Cav2 calcium channels
H. William Tedford et al.
PHARMACOLOGICAL REVIEWS (2006)
The orofacial formalin test in the mouse: A behavioral model for studying physiology and modulation of trigeminal nociception
Philippe Luccarini et al.
JOURNAL OF PAIN (2006)
Dynorphin A activates bradykinin receptors to maintain neuropathic pain
Josephine Lai et al.
NATURE NEUROSCIENCE (2006)
Non-peptide antagonists for kinin B1 receptors:: never insights into their therapeutic potential for the management of inflammation and pain
Maria M. Campos et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2006)
Primary afferent NMDA receptors increase dorsal horn excitation and mediate opiate tolerance in neonatal rats
Jinsong Zeng et al.
JOURNAL OF NEUROSCIENCE (2006)
Identification of the α2-δ-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin
Mark J. Field et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
TRPV1: a therapeutic target for novel analgesic drugs?
Arpad Szallasi et al.
TRENDS IN MOLECULAR MEDICINE (2006)
Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane
Alexander T. Stein et al.
JOURNAL OF GENERAL PHYSIOLOGY (2006)
Differential effects of endogenous cysteine analogs on peripheral thermal nociception in intact rats
Sriyani Pathirathna et al.
PAIN (2006)
Pannexin-1 mediates large pore formation and interleukin-1β release by the ATP-gated P2X7 receptor
Pablo Pelegrin et al.
EMBO JOURNAL (2006)
CaV3 T-type calcium channel isoforms differentially distribute to somatic and dendritic compartments in rat central neurons
Bruce E. McKay et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2006)
Calcium channel α2δ1 subunit mediates spinal hyperexcitability in pain modulation
Chun-Ying Li et al.
PAIN (2006)
Acid-sensing ion channel 1a is a postsynaptic proton receptor that affects the density of dendritic spines
Xiang-ming Zha et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Pain sensitivity in mice lacking the Cav2.1α1 subunit of P/Q-type Ca2+ channels
S. Luvisetto et al.
NEUROSCIENCE (2006)
Molecular and immunohistochemical studies in expression of voltage-dependent Ca2+ channels in dorsal root ganglia from streptozotocin-induced diabetic mice
Mariko Umeda et al.
LIFE SCIENCES (2006)
Alternative splicing of the CaV1.3 channel IQ domain, a molecular switch for Ca2+-dependent inactivation within auditory hair cells
Yiru Shen et al.
JOURNAL OF NEUROSCIENCE (2006)
Acid-sensing ion channels: advances, questions and therapeutic opportunities
John A. Wemmie et al.
TRENDS IN NEUROSCIENCES (2006)
Distinct ASIC currents are expressed in rat putative nociceptors and are modulated by nerve injury
Olivier Poirot et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
Alternative splicing in the C-terminus of CaV2.2 controls expression and gating of N-type calcium channels
Andrew J. Castiglioni et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
Endogenous nociceptin/orphanin FQ signalling produces opposite spinal antinociceptive and supraspinal pronociceptive effects in the mouse formalin test: Pharmacological and genetic evidences
Anna Rizzi et al.
PAIN (2006)
Sustained currents through ASIC3 ion channels at the modest pH changes that occur during myocardial ischemia
Junichi Yagi et al.
CIRCULATION RESEARCH (2006)
Inhibition of protein tyrosine kinases attenuated Aβ-fiber-evoked synaptic transmission in spinal dorsal horn of rats with sciatic nerve transection
Xiao-Dong Hu et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2006)
Protease-activated receptor 2 sensitizes TRPV1 by protein kinase Cε- and A-dependent mechanisms in rats and mice
Silvia Amadesi et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain
Clare J. Proudfoot et al.
CURRENT BIOLOGY (2006)
Both Ca2+-permeable and -impermeable AMPA receptors contribute to primary synaptic drive onto rat dorsal horn neurons
Chi-Kun Tong et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
The synthesis, structural characterization, and receptor specificity of the α-conotoxin Vc1.1
Richard J. Clark et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
P2X receptors as cell-surface ATP sensors in health and disease
Baljit S. Khakh et al.
NATURE (2006)
Purinoceptors in microglia and neuropathic pain
Tuan Trang et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2006)
Experimental colitis modulates the functional properties of NMDA receptors in dorsal root ganglia neurons
Jichang Li et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2006)
PDZ domains at excitatory synapses: Potential molecular targets for persistent pain treatment
Yuan-Xiang Tao et al.
CURRENT NEUROPHARMACOLOGY (2006)
Blocking T-type Ca2+ channels with efonidipine decreased plasma aldosterone concentration in healthy volunteers
Satoshi Okayama et al.
HYPERTENSION RESEARCH (2006)
Voltage-gated calcium channels and idiopathic generalized epilepsies
Houman Khosravani et al.
PHYSIOLOGICAL REVIEWS (2006)
Antisense knock down of TRPA1, but not TRPM8. alleviates cold hyperalgesia after spinal nerve ligation in rats
Hirokazu Katsura et al.
EXPERIMENTAL NEUROLOGY (2006)
Synaptic amplifier of inflammatory pain in the spinal dorsal horn
Hiroshi Ikeda et al.
SCIENCE (2006)
Rapid ATP-induced release of matrix metalloproteinase 9 is mediated by the P2X7 receptor
Ben J. Gu et al.
BLOOD (2006)
A C-terminal lysine that controls human P2X4 receptor desensitization
Samuel J. Fountain et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Spinal NMDA receptor phosphorylation correlates with the presence of neuropathic signs following peripheral nerve injury in the rat
Camilla Ultenius et al.
NEUROSCIENCE LETTERS (2006)
The effect of neurotrophic factors on morphology, TRPV1 expression and capsaicin responses of cultured human DRG sensory neurons
U. Anand et al.
NEUROSCIENCE LETTERS (2006)
Possible involvement of increase in spinal fibronectin a following peripheral nerve injury in upregulation of microglial P2X4, a key molecule for mechanical allodynia
K Nasu-Tada et al.
GLIA (2006)
Intrathecal ziconotide in the treatment of chronic nonmalignant pain: A randomized, double-blind, placebo-controlled clinical trial
MS Wallace et al.
NEUROMODULATION (2006)
The P2X7 receptor:: A key player in IL-1 processing and release
Davide Ferrari et al.
JOURNAL OF IMMUNOLOGY (2006)
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents
DM Bautista et al.
CELL (2006)
Disinhibition opens the gate to pathological pain signaling in superficial neurokinin 1 receptor-expressing neurons in rat spinal cord
C Torsney et al.
JOURNAL OF NEUROSCIENCE (2006)
Regulation of sensory neuron-specific acid-sensing ion channel 3 by the adaptor protein Na+/H+ exchanger regulatory factor-1
E Deval et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
NMDA receptors in layer 4 spiny stellate cells of the mouse barrel cortex contain the NR2C subunit
AM Binshtok et al.
JOURNAL OF NEUROSCIENCE (2006)
Congenital insensitivity to pain - review and report of a case with dental implications
J Butler et al.
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY (2006)
ORL1 receptor-mediated internalization of N-type calcium channels
C Altier et al.
NATURE NEUROSCIENCE (2006)
NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels
XM Zhang et al.
EMBO JOURNAL (2005)
Heat activation of TRPM5 underlies thermal sensitivity of sweet taste
K Talavera et al.
NATURE (2005)
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
JAM Coull et al.
NATURE (2005)
Spinal L-type calcium channel blockade abolishes opioid-induced sensory hypersensitivity and antinociceptive tolerance
A Dogrul et al.
ANESTHESIA AND ANALGESIA (2005)
International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels
WA Catterall et al.
PHARMACOLOGICAL REVIEWS (2005)
Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death
J Gao et al.
NEURON (2005)
Functional NR2B- and NR2D-containing NMDA receptor channels in rat substantia nigra dopaminergic neurones
S Jones et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Subunit arrangement and function in NMDA receptors
H Furukawa et al.
NATURE (2005)
N-methyl-D-glucamine and propidium dyes utilize different permeation pathways at rat P2X7 receptors
LH Jiang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2005)
TRPV4 mediates pain-related behavior induced by mild hypertonic stimuli in the presence of inflammatory mediator
N Alessandri-Haber et al.
PAIN (2005)
Involvement of N-methyl-D-aspartate-type glutamate receptor εI and ε4 subunits in tonic inflammatory pain and neuropathic pain
M Hizue et al.
NEUROREPORT (2005)
Low dose of S(+)-ketamine prevents long-term potentiation in pain pathways under strong opioid analgesia in the rat spinal cord in vivo
J Benrath et al.
BRITISH JOURNAL OF ANAESTHESIA (2005)
Functional aspects and mechanisms of TRPV1 involvement in neurogenic inflammation that leads to thermal hyperalgesia
R Planells-Cases et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2005)
Different contributions of ASIC channels 1a, 2, and 3 in gastrointestinal mechanosensory function
AJ Page et al.
GUT (2005)
Fyn kinase-mediated phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of neuropathic pain
T Abe et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Modulation of Ca2+ channels by opioid receptor-like 1 receptors natively expressed in rat stellate ganglion neurons innervating cardiac muscle
V Ruiz-Velasco et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP
DA Cockayne et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Electrophysiological and in vivo characterization of A-317567, a novel blocker of acid sensing ion channels
GR Dubé et al.
PAIN (2005)
Bradykinin produces pain hypersensitivity by potentiating spinal cord glutamatergic synaptic transmission
HB Wang et al.
JOURNAL OF NEUROSCIENCE (2005)
Pungent products from garlic activate the sensory ion channel TRPA1
DM Bautista et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Vesicle-mediated transport and release of CCL21 in endangered neurons: A possible explanation for microglia activation remote from a primary lesion
EK de Jong et al.
JOURNAL OF NEUROSCIENCE (2005)
Effects of N-methyl-D-aspartate receptor antagonists on acute morphine-induced and I-methadone-induced antinociception in mice
BD Fischer et al.
JOURNAL OF PAIN (2005)
G protein-gated inhibitory module of N-type (CaV2.2) Ca2+ channels
HL Agler et al.
NEURON (2005)
Electrophysiological differences between nociceptive and non-nociceptive dorsal root ganglion neurones in the rat in vivo
X Fang et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Ionotropic glutamate receptors are expressed in GABAergic terminals in the rat superficial dorsal horn
CR Lu et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2005)
Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing
K Nagata et al.
JOURNAL OF NEUROSCIENCE (2005)
Attenuated fever response in mice lacking TRPV1
T Iida et al.
NEUROSCIENCE LETTERS (2005)
Inhibition by spinal μ- and δ-opioid agonists of afferent-evoked substance P release
I Kondo et al.
JOURNAL OF NEUROSCIENCE (2005)
Spinal G-protein-gated potassium channels contribute in a dose-dependent manner to the analgesic effect of μ- and δ- but not κ-opioids
CL Marker et al.
JOURNAL OF NEUROSCIENCE (2005)
Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain
IP Chessell et al.
PAIN (2005)
Atomic force microscopy imaging demonstrates that P2X2 receptors are trimers but that P2X6 receptor subunits do not oligomerize
NP Barrera et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Acid-sensing properties in rat gastric sensory neurons from normal and ulcerated stomach
T Sugiura et al.
JOURNAL OF NEUROSCIENCE (2005)
Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution
N Unwin
JOURNAL OF MOLECULAR BIOLOGY (2005)
Presynaptic 'Cav2.3-containing' E-type Ca2+ channels share dual roles during neurotransmitter release
MA Kamp et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Homo- and heteromeric assembly of TRPV channel subunits
N Hellwig et al.
JOURNAL OF CELL SCIENCE (2005)
Activation of the melastatin-related cation channel TRMP3 by D-erythro-sphingosine
C Grimm et al.
MOLECULAR PHARMACOLOGY (2005)
Association of CaV1.3 L-type calcium channels with shank
H Zhang et al.
JOURNAL OF NEUROSCIENCE (2005)
Neuropathic pain and spinal microglia: a big problem from molecules in 'small' glia
M Tsuda et al.
TRENDS IN NEUROSCIENCES (2005)
Silencing of the Cav3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception
E Bourinet et al.
EMBO JOURNAL (2005)
Sensitization of TRPV1 by EP1 and IP reveals peripheral nociceptive mechanism of prostaglandins
Tomoko Moriyama et al.
MOLECULAR PAIN (2005)
NR2 subunit-depenclence of NMDA receptor channel block by external Mg2+
A Qian et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Early painful diabetic neuropathy is associated with differential changes in the expression and function of vanilloid receptor 1
SS Hong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Gene knockdown with intrathecal siRNA of NMDA receptor NR2B subunit reduces formalin-induced nociception in the rat
PH Tan et al.
GENE THERAPY (2005)
Ethosuximide reverses paclitaxel- and vincristine-induced painful peripheral neuropathy
SJL Flatters et al.
PAIN (2004)
Biochemical pharmacology of the vanilloid receptor TRPV1 - An update
DN Cortright et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2004)
Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a
O Yermolaieva et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Unique domain anchoring of Src to synaptic NMDA receptors via the mitochondrial protein NADH dehydrogenase subunit 2
JR Gingrich et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons
S Diochot et al.
EMBO JOURNAL (2004)
Gabapentin may inhibit synaptic transmission in the mouse spinal cord dorsal horn through a preferential block of P/Q-type Ca2+ channels
K Bayer et al.
NEUROPHARMACOLOGY (2004)
Protease-activated receptors: Contribution to physiology and disease
VS Ossovskaya et al.
PHYSIOLOGICAL REVIEWS (2004)
Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin
M Bandell et al.
NEURON (2004)
Presynaptic NMDA receptors modulate glutamate release from primary sensory neurons in rat spinal cord dorsal horn
R Bardoni et al.
JOURNAL OF NEUROSCIENCE (2004)
Effects of capsaicin on the sensorimotor function of the proximal stomach in humans
KJ Lee et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2004)
Agonist-independent modulation of N-type calcium channels by ORL1 receptors
AM Beedle et al.
NATURE NEUROSCIENCE (2004)
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
SE Jordt et al.
NATURE (2004)
Cell-specific alternative splicing increases calcium channel current density in the pain pathway
TJ Bell et al.
NEURON (2004)
Intrathecal ziconotide in the treatment of refractory pain in patients with cancer or AIDS - A randomized controlled trial
PS Staats et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2004)
Aβ-fiber nociceptive primary afferent neurons:: a review of incidence and properties in relation to other afferent A-fiber neurons in mammals
L Djouhri et al.
BRAIN RESEARCH REVIEWS (2004)
Role of T-type calcium current in identified D-hair mechanoreceptor neurons studied in vitro
AS Dubreuil et al.
JOURNAL OF NEUROSCIENCE (2004)
Spinal dorsal horn calcium channel α2δ-1 subunit upregulation contributes to peripheral nerve injury-induced tactile allodynia
CY Li et al.
JOURNAL OF NEUROSCIENCE (2004)
Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization
Y Kawasaki et al.
JOURNAL OF NEUROSCIENCE (2004)
Neuroprotection in ischemia: Blocking calcium-permeable acid-sensing ion channels
ZG Xiong et al.
CELL (2004)
The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel
HH Chuang et al.
NEURON (2004)
Molecular properties of ATP-gated P2X receptor ion channels
C Vial et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2004)
Warm temperature-sensitive transient receptor potential vanilloid 4 (TRPV4) plays an essential role in thermal hyperalgesia
H Todaka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Activation of protein kinase C antagonizes the opioid inhibition of calcium current in rat spinal dorsal horn neurons
JJ Lee et al.
BRAIN RESEARCH (2004)
The α2δ auxiliary subunit reduces affinity of ω-conotoxins for recombinant N-type (Cav2.2) calcium channels
J Mould et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels
T Voets et al.
NATURE (2004)
Changes in tissue pH and temperature after incision indicate acidosis may contribute to postoperative pain
YC Woo et al.
ANESTHESIOLOGY (2004)
Chemical nociception in the jejunum induced by capsaicin
B Schmidt et al.
GUT (2004)
Stomatin modulates gating of acid-sensing ion channels
MP Price et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Differential sensitivity of N- and P/Q-type Ca2+ channel currents to a μ opioid in isolectin B4-positive and -negative dorsal root ganglion neurons
ZZ Wu et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
Reanalysis of P2X7 receptor expression in rodent brain
JA Sim et al.
JOURNAL OF NEUROSCIENCE (2004)
Plasma membrane expression of T-type calcium channel α1 subunits is modulated by high voltage-activated auxiliary subunits
SJ Dubel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Peripheral noxious stimulation induces phosphorylation of the NMDA receptor NR1 subunit at the PKC-dependent site, serine-896, in spinal cord dorsal horn neurons
GJ Brenner et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
Auxiliary subunit regulation of high-voltage activated calcium channels expressed in mammalian cells
T Yasuda et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function
AJ Page et al.
GASTROENTEROLOGY (2004)
Synaptic distribution of the NR1, NR2A and NR2B subunits of the N-methyl-D-aspartate receptor in the rat lumbar spinal cord revealed with an antigen-unmasking technique
GG Nagy et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
Ziconotide: Neuronal calcium channel blocker for treating severe chronic pain
GP Miljanich
CURRENT MEDICINAL CHEMISTRY (2004)
Acid-induced pain and its modulation in humans
NG Jones et al.
JOURNAL OF NEUROSCIENCE (2004)
Evidence for an exclusive antinociceptive effect of nociceptin/orphanin FQ, an endogenous ligand for the ORL1 receptor, in two animal models of neuropathic pain
C Courteix et al.
PAIN (2004)
Novel mechanism of enhanced nociception in a model of AIDS therapy-induced painful peripheral neuropathy in the rat
EK Joseph et al.
PAIN (2004)
PSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+-gated current
AM Hruska-Hageman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Deletion of N-type calcium channels alters ethanol reward and reduces ethanol consumption in mice
PM Newton et al.
JOURNAL OF NEUROSCIENCE (2004)
A developmental switch in acute sensitization of small dorsal root ganglion (DRG) neurons to capsaicin or noxious heating by NGF
WG Zhu et al.
JOURNAL OF NEUROPHYSIOLOGY (2004)
2-aminoethoxydiphenyl borate activates and sensitizes the heat-gated ion channel TRPV3
MK Chung et al.
JOURNAL OF NEUROSCIENCE (2004)
Jejunal afferent nerve sensitivity in wild-type and TRPV1 knockout mice
WF Rong et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
NMDA receptors are movin' in
Y Nong et al.
CURRENT OPINION IN NEUROBIOLOGY (2004)
Modulation of morphine analgesia by site-specific N-methyl-D-aspartate receptor antagonists: dependence on sex, site of antagonism, morphine dose, and time
KVS Nemmani et al.
PAIN (2004)
Electrophysiological characterization of N-methyl-D-aspartate receptors in rat dorsal root ganglia neurons
JC Li et al.
PAIN (2004)
Characterization of N-methyl-D-aspartate receptor subunits responsible for postoperative pain
W Nishimura et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2004)
Transcript scanning reveals novel and extensive splice variations in human L-type voltage-gated calcium channel, Cav1.2 α1 subunit
ZZ Tang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Characterization of acid-sensing ion channels in dorsal horn neurons of rat spinal cord
LJ Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Group I metabotropic glutamate receptor NMDA receptor coupling and signaling cascade mediate spinal dorsal horn NMDA receptor 2B tyrosine phosphorylation associated with inflammatory hyperalgesia
W Guo et al.
JOURNAL OF NEUROSCIENCE (2004)
Molecular mechanisms underlying calcium current modulation by nociceptin
KY Yeon et al.
NEUROREPORT (2004)
Brain-derived neurotrophic factor induces NMDA receptor subunit one phosphorylation via ERK and PKC in the rat spinal cord
SE Slack et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
ASIC2b-dependent regulation of ASIC3, an essential acid-sensing ion channel subunit in sensory neurons via the partner protein PICK-1
E Deval et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia
S Amadesi et al.
JOURNAL OF NEUROSCIENCE (2004)
Proteinase-activated receptor 2-mediated potentiation of transient receptor potential vanilloid subfamily 1 activity reveals a mechanism for proteinase-induced inflammatory pain
Y Dai et al.
JOURNAL OF NEUROSCIENCE (2004)
Peripheral inflammation-induced increase of AMPA-mediated currents and Ca2+ transients in the presence of cyclothiazide in the rat substantia gelatinosa neurons
N Voitenko et al.
CELL CALCIUM (2004)
How nerve growth factor drives physiological and inflammatory expressions of acid-sensing ion channel 3 in sensory neurons
J Mamet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
G protein modulation of voltage-gated calcium channels
AC Dolphin
PHARMACOLOGICAL REVIEWS (2003)
Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans
W Liedtke et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Abnormal coronary function in mice deficient in α1H T-type Ca2+ channels
CC Chen et al.
SCIENCE (2003)
Abnormal osmotic regulation in trpv4-/- mice
W Liedtke et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
ERK integrates PKA and PKC signaling in superficial dorsal horn neurons.: I.: Modulation of A-type K+ currents
HJ Hu et al.
JOURNAL OF NEUROPHYSIOLOGY (2003)
Reversal of experimental neuropathic pain by T-type calcium channel blockers
A Dogrul et al.
PAIN (2003)
Voltage dependence of the Ca2+-activated cation channel TRPM4
B Nilius et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury
M Tsuda et al.
NATURE (2003)
Nerve growth factor and gastric hyperalgesia in the rat
K Lamb et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2003)
Hypotonicity induces TRPV4-mediated nociception in rat
N Alessandri-Haber et al.
NEURON (2003)
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels
H Watanabe et al.
NATURE (2003)
TRPM5 is a voltage-modulated and Ca2+-activated monovalent selective cation channel
T Hofmann et al.
CURRENT BIOLOGY (2003)
Facilitation of spinal NMDA receptor currents by spillover of synaptically released glycine
S Ahmadi et al.
SCIENCE (2003)
Impaired pressure sensation in mice lacking TRPV4
M Suzuki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
γ Subunit of voltage-activated calcium channels
MG Kang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
1,4-dihydropyridines as calcium channel ligands and privileged structures
DJ Triggle
CELLULAR AND MOLECULAR NEUROBIOLOGY (2003)
Unaltered pain-related behavior in mice lacking NMDA receptor GluRε1 subunit
AB Petrenko et al.
NEUROSCIENCE RESEARCH (2003)
Determinants of inhibition of transiently expressed voltage-gated calcium channels by ω-conotoxins GVIA and MVIIA
ZP Feng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Primary afferent terminals that express presynaptic NR1 in rats are mainly from myelinated, mechanosensitive fibers
CR Lu et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2003)
Effect of resiniferatoxin on the noxious heat threshold temperature in the rat:: a novel heat allodynia model sensitive to analgesics
R Almási et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
painless, a Drosophila gene essential for nociception
WD Tracey et al.
CELL (2003)
EphB receptors and ephrin-B ligands regulate spinal sensory connectivity and modulate pain processing
AA Battaglia et al.
NATURE NEUROSCIENCE (2003)
Effects of neuropeptide SF and related peptides on acid sensing ion channel 3 and sensory neuron excitability
E Deval et al.
NEUROPHARMACOLOGY (2003)
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures
GM Story et al.
CELL (2003)
Glycine binding primes NMDA receptor internalization
Y Nong et al.
NATURE (2003)
Synaptic plasticity in spinal lamina I projection neurons that mediate hyperalgesia
H Ikeda et al.
SCIENCE (2003)
Neuropathic Sensitization of Behavioral reflexes and spinal NMDA receptor/CaM kinase II interactions are disrupted in PSD-95 mutant mice
EM Garry et al.
CURRENT BIOLOGY (2003)
ω-conotoxin CVID inhibits a pharmacologically distinct voltage sensitive calcium channel associated with transmitter release from preganglionic nerve terminals
DJ Adams et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency
CLH Chan et al.
LANCET (2003)
γ1 subunit interactions within the skeletal muscle L-type voltage-gated calcium channels
J Arikkath et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1
KA Sluka et al.
PAIN (2003)
Neurological phenotype and synaptic function in mice lacking the Ca(V)1.3 alpha subunit of nueronal L-type voltage-dependent Ca2+ channels
NC Clark et al.
NEUROSCIENCE (2003)
Differential response properties of IB4-positive and -negative unmyelinated sensory neurons to protons and capsaicin
S Dirajlal et al.
JOURNAL OF NEUROPHYSIOLOGY (2003)
N-methyl-D-aspartate-induced excitation and sensitization of normal and inflamed nociceptors
J Du et al.
NEUROSCIENCE (2003)
BDNF sensitizes the response of lamina II neurons to high threshold primary afferent inputs
SM Garraway et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2003)
Plastic change of N-type Ca channel expression after preconditioning is responsible for prostaglandin E-2-induced long-lasting allodynia
K Yokoyama et al.
ANESTHESIOLOGY (2003)
Effects of A-317491, a novel and selective P2X(3)/P2X(2/3) receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration
S McGaraughty et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
Molecular physiology of low-voltage-activated T-type calcium channels
E Perez-Reyes
PHYSIOLOGICAL REVIEWS (2003)
Protein kinase C stimulates the acid-sensing ion channel ASIC2a via the PDZ domain-containing protein PICK1
A Baron et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
A-317491, a novel potent and selective nonnucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat
MF Jarvis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Injury type-specific calcium channel α2δ-1 subunit up-regulation in rat neuropathic pain models correlates with antiallodynic effects of gabapentin
ZD Luo et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Localization of N-type Ca2+ channels in the rat spinal cord following chronic constrictive nerve injury
D Cizkova et al.
EXPERIMENTAL BRAIN RESEARCH (2002)
Spinal brain-derived neurotrophic factor (BDNF) produces hyperalgesia in normal mice while antisense directed against either BDNF or trkB, prevent inflammation-induced hyperalgesia
R Groth et al.
PAIN (2002)
Treatment of ischemic brain damage by perturbing NMDA receptor-PSD-95 protein interactions
M Aarts et al.
SCIENCE (2002)
Cutting edge: A natural P451L mutation in the cytoplasmic domain impairs the function of the mouse P2X7 receptor
S Adriouch et al.
JOURNAL OF IMMUNOLOGY (2002)
Actions of intrathecal ω-conotoxins CVID, GVIA, MVIIA, and morphine in acute and neuropathic pain in the rat
DA Scott et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2002)
Analgesic profile of intrathecal P2X3 antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats
P Honore et al.
PAIN (2002)
VR1, but not P2X3, increases in the spared L4 DRG in rats with L5 spinal nerve ligation
T Fukuoka et al.
PAIN (2002)
GDNF and NGF reverse changes in repriming of TTX-sensitive Na+ currents following axotomy of dorsal root ganglion neurons
A Leffler et al.
JOURNAL OF NEUROPHYSIOLOGY (2002)
Endovanilloid signaling in pain
V Di Marzo et al.
CURRENT OPINION IN NEUROBIOLOGY (2002)
Epithelial sodium channel/degenerin family of ion channels: A variety of functions for a shared structure
S Kellenberger et al.
PHYSIOLOGICAL REVIEWS (2002)
A role for ASIC3 in the modulation of high-intensity pain stimuli
CC Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Two N-methyl-D-aspartate receptors in rat dorsal root ganglia with different subunit composition and localization
JCG Marvizón et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2002)
The multivalent PDZ domain-containing protein CIPP is a partner of acid-sensing ion channel 3 in sensory neurons
N Anzai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Effects of ablation of N- and R-type Ca2+ channels on pain transmission
H Saegusa et al.
NEUROSCIENCE RESEARCH (2002)
Defining the role for gabapentin in the treatment of trigeminal neuralgia: A retrospective study
WP Cheshire
JOURNAL OF PAIN (2002)
Tyrosine phosphatase STEP is a tonic brake on induction of long-term potentiation
KA Pelkey et al.
NEURON (2002)
A TRP channel that senses cold stimuli and menthol
AM Peier et al.
CELL (2002)
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
DD McKemy et al.
NATURE (2002)
The PDZ domain protein PICK1 and the sodium channel BNaC1 interact and localize at mechanosensory terminals of dorsal root ganglion neurons and dendrites of central neurons
A Duggan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The novel N-type calcium channel blocker, AM336, produces potent dose-dependent antinociception after intrathecal dosing in rats and inhibits substance P release in rat spinal cord slices
MT Smith et al.
PAIN (2002)
TNP-ATP, a potent P2X(3) receptor antagonist, blocks acetic acid-induced abdominal constriction in mice: comparison with reference analgesics
P Honore et al.
PAIN (2002)
Gabapentin-mediated inhibition of voltage-activated Ca2+ channel currents in cultured sensory neurones is dependent on culture conditions and channel subunit expression
DJ Martin et al.
NEUROPHARMACOLOGY (2002)
Glutamate-induced currents reveal three functionally distinct NMDA receptor populations in rat dorsal horn - Effects of peripheral nerve lesion and inflammation
U Karlsson et al.
NEUROSCIENCE (2002)
Gabapentin inhibits high-threshold calcium channel currents in cultured rat dorsal root ganglion neurones
KG Sutton et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
ASIC-like, proton-activated currents in rat hippocampal neurons
A Baron et al.
JOURNAL OF PHYSIOLOGY-LONDON (2002)
Differential facilitation of N- and P/Q-type calcium channels during trains of action potential-like waveforms
KPM Currie et al.
JOURNAL OF PHYSIOLOGY-LONDON (2002)
The DRASIC cation channel contributes to the detection of cutaneous touch and acid stimuli in mice
MP Price et al.
NEURON (2001)
Direct inhibition of T-type calcium channels by the endogenous cannabinoid anandamide
J Chemin et al.
EMBO JOURNAL (2001)
Calcium channel β subunits differentially regulate the inhibition of N-type channels by individual Gβ isoforms
ZP Feng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Novel capsaicin (VR1) and purinergic (P2X3) receptors in Hirschsprung's intestine
P Facer et al.
JOURNAL OF PEDIATRIC SURGERY (2001)
NMDA receptors as targets for drug action in neuropathic pain
CG Parsons
EUROPEAN JOURNAL OF PHARMACOLOGY (2001)
Signaling to the nucleus by an L-type calcium channel - Calmodulin complex through the MAP kinase pathway
RE Dolmetsch et al.
SCIENCE (2001)
Expression of voltage-gated calcium channel subunits in rat dorsal root ganglion neurons
SP Yusaf et al.
NEUROSCIENCE LETTERS (2001)
Zn2+ and H+ are coactivators of acid-sensing ion channels
A Baron et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Molecular and functional characterization of acid-sensing ion channel (ASIC) 1b
EL Bässler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Lactate enhances the acid-sensing Na+ channel on ischemia-sensing neurons
DC Immke et al.
NATURE NEUROSCIENCE (2001)
Differential nociceptive responses in mice lacking the αIB subunit of N-type Ca2+ channels
S Hatakeyama et al.
NEUROREPORT (2001)
Altered nociceptive response in mice deficient in the α1B subunit of the voltage-dependent calcium channel
C Kim et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2001)
Analysis of the native quaternary structure of vanilloid receptor 1
N Kedei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway
N Vergnolle et al.
NATURE MEDICINE (2001)
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
HH Chuang et al.
NATURE (2001)
Suppression of inflammatory and neuropathic pain symptoms in mice lacking the N-type Ca2+ channel
H Saegusa et al.
EMBO JOURNAL (2001)
Residue Gly1326 of the N-type calcium channel α1B subunit controls reversibility of ω-conotoxin GVIA and MVIIA block
ZP Feng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The role of δ-opioid receptor subtypes in neuropathic pain
J Mika et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2001)
Protease-activated receptors in inflammation, neuronal signaling and pain
N Vergnolle et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2001)
Comparison of the effects of MK-801, ketamine and memantine on responses of spinal dorsal horn neurones in a rat model of mononeuropathy
R Suzuki et al.
PAIN (2001)
Alternatively spliced α1G (Cav3.1) intracellular loops promote specific T-type Ca2+ channel gating properties
J Chemin et al.
BIOPHYSICAL JOURNAL (2001)
CAKβ/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus
YQ Huang et al.
NEURON (2001)
On the immunohistochemical distribution of ionotropic P2X receptors in the nucleus tractus solitarius of the rat
ST Yao et al.
NEUROSCIENCE (2001)
Developmental regulation of N-methyl-D-aspartate- and kainate-type glutamate receptor expression in the rat spinal cord
SL Stegenga et al.
NEUROSCIENCE (2001)
Modulation of BzATP and formalin induced nociception: attenuation by the P2X receptor antagonist, TNP-ATP and enhancement by the P2X(3) allosteric modulator, cibacron blue
MF Jarvis et al.
BRITISH JOURNAL OF PHARMACOLOGY (2001)
Nociceptin is a potent inhibitor of N-type Ca2+ channels in rat sympathetic ganglion neurons
KP Larsson et al.
NEUROSCIENCE LETTERS (2000)
EphB receptors interact with NMDA receptors and regulate excitatory synapse formation
MB Dalva et al.
CELL (2000)
Tyrosine-kinase-dependent recruitment of RGS12 to the N-type calcium channel
ML Schiff et al.
NATURE (2000)
Novel ω-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes
RJ Lewis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice
DA Cockayne et al.
NATURE (2000)
The mammalian sodium channel BNC1 is required for normal touch sensation
MP Price et al.
NATURE (2000)
Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors
V Souslova et al.
NATURE (2000)
Mammalian ASIC2a and ASIC3 subunits co-assemble into heteromeric proton-gated channels sensitive to Gd3+
K Babinski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Differential modulation of N-type α1B and P/Q-type α1A calcium channels by different G protein β subunit isoforms
MI Arnot et al.
JOURNAL OF PHYSIOLOGY-LONDON (2000)
Oligomerization of μ- and δ-opioid receptors -: Generation of novel functional properties
SR George et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Isolation of a tarantula toxin specific for a class of proton-gated Na+ channels
P Escoubas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Calcium channel β subunit promotes voltage-dependent modulation of α1B by Gβγ
A Meir et al.
BIOPHYSICAL JOURNAL (2000)
Spared nerve injury: an animal model of persistent peripheral neuropathic pain
I Decosterd et al.
PAIN (2000)
A new member of the acid-sensing ion channel family
AN Akopian et al.
NEUROREPORT (2000)
Voltage- and time-dependent properties of the recombinant rat vanilloid receptor (rVR1)
MJ Gunthorpe et al.
JOURNAL OF PHYSIOLOGY-LONDON (2000)
ATP in human skin elicits a dose-related pain response which is potentiated under conditions of hyperalgesia
SG Hamilton et al.
BRAIN (2000)
Altered pain responses in mice lacking α1E subunit of the voltage-dependent Ca2+ channel
H Saegusa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
The role of pH and osmolarity in evoking the acetic acid-induced wiping response in a model of nociception in frogs
DT Hamamoto et al.
BRAIN RESEARCH (2000)
Impaired nociception and pain sensation in mice lacking the capsaicin receptor
MJ Caterina et al.
SCIENCE (2000)
A protein kinase C site highly conserved in P2X subunits controls the desensitization kinetics of P2X2 ATP-gated channels
É Boué-Grabot et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Distinct synaptic and extrasynaptic NMDA receptors identified in dorsal horn neurones of the adult rat spinal cord
A Momiyama
JOURNAL OF PHYSIOLOGY-LONDON (2000)
Effects of intrathecal administration of ziconotide, a selective neuronal N-type calcium channel blocker, on mechanical allodynia and heat hyperalgesia in a rat model of postoperative pain
YX Wang et al.
PAIN (2000)
Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism
M Steinhoff et al.
NATURE MEDICINE (2000)
Silent NMDA receptor-mediated synapses are developmentally regulated in the dorsal horn of the rat spinal cord
H Baba et al.
JOURNAL OF NEUROPHYSIOLOGY (2000)
Effect of G protein heterotrimer composition on coupling of neurotransmitter receptors to N-type Ca2+ channel modulation in sympathetic neurons
SW Jeong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Prostaglandin E-2-induced sensitization of bradykinin-evoked responses in rat dorsal root ganglion neurons is mediated by cAMP-dependent protein kinase A
JAM Smith et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2000)
Localization of N-methyl-D-aspartate NR2B subunits on primary sensory neurons that give rise to small-caliber sciatic nerve fibers in rats
QP Ma et al.
NEUROSCIENCE (2000)
Adverse effects associated with the intrathecal administration of ziconotide
RD Penn et al.
PAIN (2000)
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