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NDR Kinase Is Activated by RASSF1A/MST1 in Response to Fas Receptor Stimulation and Promotes Apoptosis
Anton Vichalkovski et al.
CURRENT BIOLOGY (2008)
Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling
Mitsunori Ota et al.
DEVELOPMENT (2008)
The TEAD/TEF family protein scalloped mediates transcriptional output of the hippo growth-regulatory pathway
Shian Wu et al.
DEVELOPMENTAL CELL (2008)
The TEAD/TEF family of transcription factor scalloped mediates hippo signaling in organ size control
Lei Zhang et al.
DEVELOPMENTAL CELL (2008)
A crucial role of WW45 in developing epithelial tissues in the mouse
Joo-Hyeon Lee et al.
EMBO JOURNAL (2008)
YAP regulates neural progenitor cell number via the TEA domain transcription factor
Xinwei Cao et al.
GENES & DEVELOPMENT (2008)
TEAD mediates YAP-dependent gene induction and growth control
Bin Zhao et al.
GENES & DEVELOPMENT (2008)
Expression of Yes-associated protein in common solid tumors
Angela A. Steinhardt et al.
HUMAN PATHOLOGY (2008)
TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway
Qun-Ying Lei et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Redundant roles of Tead1 and Tead2 in notochord development and the regulation of cell proliferation and survival
Atsushi Sawada et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Yap1 phosphorylation by c-AbI is a critical step in selective activation of proapoptotic genes in response to DNA damage
Dan Levy et al.
MOLECULAR CELL (2008)
Somatic mutations affect key pathways in lung adenocarcinoma
Li Ding et al.
NATURE (2008)
TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal
Xaralabos Varelas et al.
NATURE CELL BIOLOGY (2008)
Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos
Noriyuki Nishioka et al.
MECHANISMS OF DEVELOPMENT (2008)
Unraveling the microenvironmental influences on the normal mammary gland and breast cancer
Britta Weigelt et al.
SEMINARS IN CANCER BIOLOGY (2008)
Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ
Ryosuke Makita et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2008)
Yes-Associated Protein (YAP) is a critical mediator of c-Jun-dependent apoptosis
S. A. Danovi et al.
CELL DEATH AND DIFFERENTIATION (2008)
YAP1 increases organ size and expands undifferentiated progenitor cells
Fernando D. Camargo et al.
CURRENT BIOLOGY (2007)
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
Bin Zhao et al.
GENES & DEVELOPMENT (2007)
Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development
Rieko Yagi et al.
DEVELOPMENT (2007)
A Sveinsson's chorioretinal atrophy-associated missense mutation in mouse Tead1 affects its interaction with the co-factors YAP and TAZ
Michinori Kitagawa
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Elucidation of a universal size-control mechanism in Drosophila and mammals
Jixin Dong et al.
CELL (2007)
RASSRA elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the P73 tumor suppressor protein
David Matallanas et al.
MOLECULAR CELL (2007)
Lats2 is an essential mitotic regulator required for the coordination of cell division
Norikazu Yabuta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1
Zakir Hossain et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The RUNX2 transcrition factor cooperates with the YES-Associated protein, YAP65, to promote cell transformation
Michele I. Vitolol et al.
CANCER BIOLOGY & THERAPY (2007)
The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73
D. Levy et al.
CELL DEATH AND DIFFERENTIATION (2007)
Wnt/β-catenin signaling in development and disease
Hans Clevers
CELL (2006)
A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization
Yael Aylon et al.
GENES & DEVELOPMENT (2006)
Matrix elasticity directs stem cell lineage specification
Adam J. Engler et al.
CELL (2006)
Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon
Michael Overholtzer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Activation of sterile20-like kinase 1 in proteasome inhibitor bortezomib-induced apoptosis in oncogenic K-ras-transformed cells
Fuminori Teraishi et al.
CANCER RESEARCH (2006)
A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span
Maria K. Lehtinen et al.
CELL (2006)
p130-Angiomotin associates to actin and controls endothelial cell shape
M Ernkvist et al.
FEBS JOURNAL (2006)
The tumor suppressors merlin and expanded function cooperatively to modulate receptor endocytosis and signaling
S Maitra et al.
CURRENT BIOLOGY (2006)
Role of the tumor suppressor RASSF1A in Mst1-medated apoptosis
HJ Oh et al.
CANCER RESEARCH (2006)
Defects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65
EM Morin-Kensicki et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
F Hamaratoglu et al.
NATURE CELL BIOLOGY (2006)
Tensional homeostasis and the malignant phenotype
MJ Paszek et al.
CANCER CELL (2005)
TAZ, a transcriptional modulator of mesenchymal stem cell differentiation
JH Hong et al.
SCIENCE (2005)
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila homolog of YAP
JB Huang et al.
CELL (2005)
The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA damage
S Strano et al.
MOLECULAR CELL (2005)
The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1
EH Chan et al.
ONCOGENE (2005)
A novel TEAD1 mutation is the causative allele in Sveinsson's chorioretinal atrophy (helicoid peripapillary chorioretinal degeneration)
R Fossdal et al.
HUMAN MOLECULAR GENETICS (2004)
TAZ interacts with TTF-1 and regulates expression of surfactant protein-C
KS Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Ligand-regulated association of ErbB-4 to the transcriptional co-activator YAP65 controls transcription at the nuclear level
J Omerovic et al.
EXPERIMENTAL CELL RESEARCH (2004)
Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment
R McBeath et al.
DEVELOPMENTAL CELL (2004)
Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity
JP McPherson et al.
EMBO JOURNAL (2004)
Rote of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1
E O'Neill et al.
SCIENCE (2004)
Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras
M Praskova et al.
BIOCHEMICAL JOURNAL (2004)
Tumor suppressor WARTS ensures genomic integrity by regulating both mitotic progression and G1 tetraploidy checkpoint function
S Iida et al.
ONCOGENE (2004)
WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus
A Komuro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis
KF Harvey et al.
CELL (2003)
Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase
WL Cheung et al.
CELL (2003)
NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions
D Lallemand et al.
GENES & DEVELOPMENT (2003)
Transcriptional coactivation of bone-specific transcription factor Cbfa1 by TAZ
CB Cui et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis
S Basu et al.
MOLECULAR CELL (2003)
salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
N Tapon et al.
CELL (2002)
Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-β/Smad signaling
O Ferrigno et al.
ONCOGENE (2002)
Identification of a novel Ras-regulated proapoptotic pathway
A Khokhlatchev et al.
CURRENT BIOLOGY (2002)
TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm
A Vassilev et al.
GENES & DEVELOPMENT (2001)
Both phosphorylation and caspase-mediated cleavage contribute to regulation of the Ste20-like protein kinase Mst1 during CD95/Fas-induced apoptosis
JD Graves et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Physical interaction with Yes-associated protein enhances p73 transcriptional activity
S Strano et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins
F Kanai et al.
EMBO JOURNAL (2000)
Functional analysis of the neurofibromatosis type 2 protein by means of disease-causing point mutations
RP Stokowski et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2000)
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