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JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
The kidney-specific WNK1 isoform is induced by aldosterone and stimulates epithelial sodium channel-mediated Na+ transport
A Náray-Fejes-Tóth et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Renal expression of osmotically responsive cation channel TRPV4 is restricted to water-impermeant nephron segments
W Tian et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2004)
Autism as a disorder of neural information processing: directions for research and targets for therapy
MK Belmonte et al.
MOLECULAR PSYCHIATRY (2004)
Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertension
XS Min et al.
STRUCTURE (2004)
Cloning, genomic organization, alternative splicing and expression analysis of the human gene RWK3 (PRKWNK3)
S Holden et al.
GENE (2004)
Analysis of insulin signalling by RNAi-based gene silencing
QL Zhou et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2004)
Paracellular Cl- permeability is regulated by WNK4 kinase:: Insight into normal physiology and hypertension
KT Kahle et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Comparison of WNK4 and WNK1 kinase and inhibiting activities
ZH Wang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
A mutation in the HSN2 gene causes sensory neuropathy type II in a Lebanese family
JB Rivière et al.
ANNALS OF NEUROLOGY (2004)
Sodium and potassium handling by the aldosterone-sensitive distal nephron: the pivotal role of the distal and connecting tubule
P Meneton et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2004)
Identification of 108 SNPs in TSC, WNK1, and WNK4 and their association with hypertension in a Japanese general population
Y Kokubo et al.
JOURNAL OF HUMAN GENETICS (2004)
Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system -: Evidence for a scaffolding role of the kinase
K Piechotta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
A protein interaction map of Drosophila melanogaster
L Giot et al.
SCIENCE (2003)
Constitutive EGFR signaling confers a motile phenotype to neural stem cells
JA Boockvar et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2003)
WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion
KT Kahle et al.
NATURE GENETICS (2003)
Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5
JGJ Hoenderop et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Multiple promoters in the WNK1 gene: One controls expression of a kidney-specific kinase-defective isoform
C Delaloy et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
BP Zambrowicz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Abnormal osmotic regulation in trpv4-/- mice
W Liedtke et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Association of EDNRA, but not WNK4 or FKBP1B, polymorphisms with essential hypertension
AV Benjafield et al.
CLINICAL GENETICS (2003)
WNK1, a gene within a novel blood pressure control pathway, tissue-specifically generates radically different isoforms with and without a kinase domain
M O'Reilly et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2003)
PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1)
BFX Dowd et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Impaired osmotic sensation in mice lacking TRPV4
A Mizuno et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
Inflammatory pseudotumor of the spleen associated with a clonal Epstein-Barr virus genome - Case report and review of the literature
JT Lewis et al.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2003)
Genetic variants of WNK4 in Whites and African Americans with hypertension
PM Erlich et al.
HYPERTENSION (2003)
Familial hyperkalemic hypertension:: Phenotypic analysis in a large family with the WNK1 deletion mutation
JM Achard et al.
AMERICAN JOURNAL OF MEDICINE (2003)
Role of tumor-associated gangliosides in cancer progression
S Birklé et al.
BIOCHIMIE (2003)
WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl- -: transporting epithelia
KA Choate et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Molecular pathogenesis of inherited hypertension with hyperkalemia: The Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4
FH Wilson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Regulation of WNK1 by an autoinhibitory domain and autophosphorylation
BE Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The protein kinase complement of the human genome
G Manning et al.
SCIENCE (2002)
Compilation and characterization of a novel WNK family of protein kinases in Arabiodpsis thaliana with reference to circadian rhythms
N Nakamichi et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2002)
The K-Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum
HC Howard et al.
NATURE GENETICS (2002)
Molecular characterization of the murine Slc26a6 anion exchanger: functional comparison with Slc26a1
QH Xie et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2002)
Genome-wide detection of tissue-specific alternative splicing in the human transcriptome
Q Xu et al.
NUCLEIC ACIDS RESEARCH (2002)
Rac-PAK signaling stimulates extracellular signal- regulated kinase (ERK) activation by regulating formation of MEKI-ERK complexes
ST Eblen et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Role of synaptotagmin in Ca2+-triggered exocytosis
WC Tucker et al.
BIOCHEMICAL JOURNAL (2002)
Genetic signature of oligoastrocytomas correlates with tumor location and denotes distinct molecular subsets
W Mueller et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
The APRR3 component of the clock-associated APRR1/TOC1 quintet is phosphorylated by a novel protein kinase belonging to the WNK family, the gene for which is also transcribed rhythmically in Arabidopsis thaliana
M Murakami-Kojima et al.
PLANT AND CELL PHYSIOLOGY (2002)
Functional characterization of three novel tissue-specific anion exchangers SLC26A7,-A8, and-A9
H Lohi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway
LC Coles et al.
ONCOGENE (2002)
Distribution of transcellular calcium and sodium transport pathways along mouse distal nephron
J Loffing et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2001)
Akt1/PKBα is required for normal growth but dispensable for maintenance of glucose homeostasis in mice
H Cho et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
WNK kinases, a novel protein kinase subfamily in multi-cellular organisms
F Veríssimo et al.
ONCOGENE (2001)
Growth retardation and increased apoptosis in mice with homozygous disruption of the akt1 gene
WS Chen et al.
GENES & DEVELOPMENT (2001)
Human hypertension caused by mutations in WNK kinases
FH Wilson et al.
SCIENCE (2001)
SLC26A2 (diastrophic dysplasia sulfate transporter) is expressed in developing and mature cartilage but also in other tissues and cell types
S Haila et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2001)
Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells
F Knauf et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Multiple WW domains, but not the C2 domain, are required for inhibition of the epithelial Na+ channel by human Nedd4
PM Snyder et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKBβ)
H Cho et al.
SCIENCE (2001)
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
JM Kyriakis et al.
PHYSIOLOGICAL REVIEWS (2001)
Identification and characterization of a novel human vanilloid receptor-like protein, VRL-2
NS Delany et al.
PHYSIOLOGICAL GENOMICS (2001)
Circadian regulation of cGMP-gated cationic channels of chick retinal cones: Erk MAP kinase and Ca2+/calmodulin-dependent protein kinase II
GYP Ko et al.
NEURON (2001)
Circadian activation of bullfrog retinal mitogen-activated protein kinase associates with oscillator function
Y Harada et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Inactivation of Smad-transforming growth factor β signaling by Ca2+-calmodulin-dependent protein kinase II
SJ Wicks et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor
W Liedtke et al.
CELL (2000)
Discrimination of GLUT4 vesicle trafficking from fusion using a temperature-sensitive Munc18c mutant
DC Thurmond et al.
EMBO JOURNAL (2000)
WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II
BE Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Rho family proteins in cell adhesion and cell migration
EE Evers et al.
EUROPEAN JOURNAL OF CANCER (2000)
PSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and regulates actin cytoskeletal organization
TM Moore et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas
JS Smith et al.
JOURNAL OF CLINICAL ONCOLOGY (2000)
Mammalian distal tubule: Physiology, pathophysiology, and molecular anatomy
RF Reilly et al.
PHYSIOLOGICAL REVIEWS (2000)
Munc18e function is required for insulin-stimulated plasma membrane fusion of GLUT4 and insulin-responsive amino peptidase storage vesicles
DC Thurmond et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination
O Staub et al.
KIDNEY INTERNATIONAL (2000)
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