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CELL DEATH AND DIFFERENTIATION (2003)
Nature's TRAIL - On a path to cancer immunotherapy
MJ Smyth et al.
IMMUNITY (2003)
IKK beta is required for prevention of apoptosis mediated by cell-bound but not by circulating TNF alpha
S Maeda et al.
IMMUNITY (2003)
Cathepsin D mediates cytochrome c release and caspase activation in human fibroblast apoptosis induced by staurosporine
AC Johansson et al.
CELL DEATH AND DIFFERENTIATION (2003)
The long form of FLIP is an activator of caspase-8 at the fas death-inducing signaling complex
O Micheau et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Defining characteristics of Types I and II apoptotic cells in response to TRAIL
N Özören et al.
NEOPLASIA (2002)
Cholestasis increases tumor necrosis factor-related apoptotis-inducing ligand (TRAIL)-R2/DR5 expression and sensitizes the liver to TRAIL-mediated cytotoxicity
H Higuchi et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Tumor necrosis factor-α-associated lysosomal permeabilization is cathepsin B dependent
NW Werneburg et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2002)
Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway
KD Tardif et al.
JOURNAL OF VIROLOGY (2002)
c-FLIPL is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis
DW Chang et al.
EMBO JOURNAL (2002)
Apoptotic pathways: Involvement of lysosomal proteases
B Turk et al.
BIOLOGICAL CHEMISTRY (2002)
Coupling endoplasmic reticulum stress to the cell death program - An Apaf-1-independent intrinsic pathway
RV Rao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Bile acid-mediated hepatocyte apoptosis and cholestatic liver disease
ME Guicciardi et al.
DIGESTIVE AND LIVER DISEASE (2002)
Plasma total and free fatty acids composition in human non-alcoholic steatohepatitis
IT De Almeida et al.
CLINICAL NUTRITION (2002)
Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice
E Cretney et al.
JOURNAL OF IMMUNOLOGY (2002)
Tumor necrosis factor alpha, but not Fas, mediates hepatocellular apoptosis in the murine ischemic liver
HA Rudiger et al.
GASTROENTEROLOGY (2002)
Cathepsin B knockout mice are resistant to tumor necrosis factor-α-mediated hepatocyte apoptosis and liver injury -: Implications for therapeutic applications
ME Guicciardi et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
Inhibition of JNK activation through NF-κB target genes
GL Tang et al.
NATURE (2001)
Induction of gadd45β by NF-κB downregulates pro-apoptotic JNK signalling
E De Smaele et al.
NATURE (2001)
Inhibition of matrix metalloproteinases blocks lethal hepatitis and apoptosis induced by tumor necrosis factor and allows safe antitumor therapy
B Wielockx et al.
NATURE MEDICINE (2001)
Nutritional and metabolic considerations in the etiology of nonalcoholic steatohepatitis
V Nehra et al.
DIGESTIVE DISEASES AND SCIENCES (2001)
Induction of cell death in human immunodeficiency virus-infected macrophages and resting memory CD4 T cells by TRAIL/Apo2L
JJ Lum et al.
JOURNAL OF VIROLOGY (2001)
Human herpesvirus 7 induces the functional up-regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) coupled to TRAIL-R1 down-modulation in CD4+ T cells
P Secchiero et al.
BLOOD (2001)
Activation of pro-death Bcl-2 family proteins and mitochondria apoptosis pathway in tumor necrosis factor-α-induced liver injury
YG Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice
T Uesugi et al.
HEPATOLOGY (2001)
Ursodeoxycholic acid 'mechanisms of action and clinical use in hepatobiliary disorders'
KN Lazaridis et al.
JOURNAL OF HEPATOLOGY (2001)
Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor
L Foghsgaard et al.
JOURNAL OF CELL BIOLOGY (2001)
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
MC Wei et al.
SCIENCE (2001)
Lysosomal protease pathways to apoptosis -: Cleavage of Bid, not pro-caspases, is the most likely route
V Stoka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Hepatocyte apoptosis is a pathologic feature of human alcoholic hepatitis
S Natori et al.
JOURNAL OF HEPATOLOGY (2001)
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bc12 and perturbing the cellular redox state
KD McCullough et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis
JP Zha et al.
SCIENCE (2000)
The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues
T Lindsten et al.
MOLECULAR CELL (2000)
Cathepsin B contributes to TNF-α-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c
ME Guicciardi et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Reovirus-induced apoptosis is mediated by TRAIL
P Clarke et al.
JOURNAL OF VIROLOGY (2000)
FADD is required for DR4-and DR5-mediated apoptosis - Lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts
AA Kuang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Temperature-sensitive differential affinity of TRAIL for its receptors - DR5 is the highest affinity receptor
A Truneh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Cysteine 230 is essential for the structure and activity of the cytotoxic ligand TRAIL
JL Bodmer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations
RM Siegel et al.
SCIENCE (2000)
Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas
T Sodeman et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2000)
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
F Urano et al.
SCIENCE (2000)
Hepatocytes sensitized to tumor necrosis factor-α cytotoxicity undergo apoptosis through caspase-dependent and caspase-independent pathways
BE Jones et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
T Nakagawa et al.
NATURE (2000)
Hepatitis C virus RNA codes for proteins and replicates: Does it also trigger the interferon response?
AD Branch
SEMINARS IN LIVER DISEASE (2000)
Prevention of hepatic apoptosis and embryonic lethality in RelA/TNFR-1 double knockout mice
ME Rosenfeld et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
Relative sensitivity of hepatitis B virus and other hepatotropic viruses to the antiviral effects of cytokines
H McClary et al.
JOURNAL OF VIROLOGY (2000)
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