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EUROPEAN JOURNAL OF NEUROSCIENCE (2003)
Understanding mental retardation in Down's syndrome using trisomy 16 mouse models
Z Galdzicki et al.
GENES BRAIN AND BEHAVIOR (2003)
Global up-regulation of chromosome 21 gene expression in the developing Down syndrome brain
R Mao et al.
GENOMICS (2003)
Regional alterations in amyloid precursor protein and nerve growth factor across age in a mouse model of Down's syndrome
CL Hunter et al.
NEUROSCIENCE RESEARCH (2003)
Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system
E Martí et al.
BRAIN RESEARCH (2003)
Induced gene expression in human brain after the split from chimpanzee
JY Gu et al.
TRENDS IN GENETICS (2003)
Behavioral comparison of 4 and 6 month-old Ts65Dn mice: Age-related impairments in working and reference memory
CL Hunter et al.
BEHAVIOURAL BRAIN RESEARCH (2003)
Toward the genetics of mammalian reproduction: Induction and mapping of gametogenesis mutants in mice
JO Ward et al.
BIOLOGY OF REPRODUCTION (2003)
Estrogen alters amyloid precursor protein as well as dendritic and cholinergic markers in a mouse model of Down syndrome
AC Granholm et al.
HIPPOCAMPUS (2003)
The neuropsychology of Down syndrome: Evidence for hippocampal dysfunction
BF Pennington et al.
CHILD DEVELOPMENT (2003)
Genome-wide detection of segmental duplications and potential assembly errors in the human genome sequence
J Cheung et al.
GENOME BIOLOGY (2003)
Spatial representation and attention in toddlers with Williams syndrome and Down syndrome
JH Brown et al.
NEUROPSYCHOLOGIA (2003)
Transcriptome analysis of human autosomal trisomy
DR FitzPatrick et al.
HUMAN MOLECULAR GENETICS (2002)
Numerous potentially functional but non-genic conserved sequences on human chromosome 21
ET Dermitzakis et al.
NATURE (2002)
A gene expression map of human chromosome 21 orthologues in the mouse
Y Gitton et al.
NATURE (2002)
Human chromosome 21 gene expression atlas in the mouse
A Reymond et al.
NATURE (2002)
Initial sequencing and comparative analysis of the mouse genome
RH Waterston et al.
NATURE (2002)
Reading, language and memory skills: A comparative longitudinal study of children with Down syndrome and their mainstream peers
A Byrne et al.
BRITISH JOURNAL OF EDUCATIONAL PSYCHOLOGY (2002)
The effects of piracetam on cognitive performance in a mouse model of Down's syndrome
TH Moran et al.
PHYSIOLOGY & BEHAVIOR (2002)
Estrogen restores cognition and cholinergic phenotype in an animal model of Down syndrome
ACE Granholm et al.
PHYSIOLOGY & BEHAVIOR (2002)
FMRI reveals brain regions mediating slow prosodic modulations in spoken sentences
M Meyer et al.
HUMAN BRAIN MAPPING (2002)
Predicting longitudinal change in language production and comprehension in individuals with Down syndrome: Hierarchical linear modeling
RS Chapman et al.
JOURNAL OF SPEECH LANGUAGE AND HEARING RESEARCH (2002)
Spatial memory dissociations in mice lacking GluR1
D Reisel et al.
NATURE NEUROSCIENCE (2002)
Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice
V Fotaki et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Breaking the neuronal sphere: Regulation of the actin cytoskeleton in neuritogenesis
JS Da Silva et al.
NATURE REVIEWS NEUROSCIENCE (2002)
Chromosomal regions containing high-density and ambiguously mapped putative single nucleotide polymorphisms (SNPs) correlate with segmental duplications in the human genome
X Estivill et al.
HUMAN MOLECULAR GENETICS (2002)
Recent segmental duplications in the human genome
JA Bailey et al.
SCIENCE (2002)
Reactivity to object and spatial novelty is normal in older Ts65Dn mice that model Down syndrome and Alzheimer's disease
LA Hyde et al.
BRAIN RESEARCH (2002)
Perinatal growth of prefrontal layer III pyramids in Down syndrome
M Vuksic et al.
PEDIATRIC NEUROLOGY (2002)
The role of genes in the etiology of specific language impairment
DVM Bishop
JOURNAL OF COMMUNICATION DISORDERS (2002)
Mnb/Dyrk1A is transiently expressed and asymmetrically segregated in neural progenitor cells at the transition to neurogenic divisions
B Hämmerle et al.
DEVELOPMENTAL BIOLOGY (2002)
Molecular-evolutionary mechanisms for genomic disorders
P Stankiewicz et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2002)
Nineteen additional unpredicted transcripts from human chromosome 21
A Reymond et al.
GENOMICS (2002)
Intra- and interspecific variation in primate gene expression patterns
W Enard et al.
SCIENCE (2002)
Craniofacial phenotypes in segmentally trisomic mouse models for Down syndrome
JT Richtsmeier et al.
AMERICAN JOURNAL OF MEDICAL GENETICS (2002)
A callosal transfer deficit in children with developmental language disorder
F Fabbro et al.
NEUROPSYCHOLOGIA (2002)
Relation of medial temporal lobe volumes to age and memory function in nondemented adults with Down's syndrome: Implications for the prodromal phase of Alzheimer's disease
JS Krasuski et al.
AMERICAN JOURNAL OF PSYCHIATRY (2002)
Mapping genetic influences on human brain structure
P Thompson et al.
ANNALS OF MEDICINE (2002)
Changes in explicit memory associated with early dementia in adults with Down's syndrome
SJ Krinsky-McHale et al.
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH (2002)
Working memory in children and adolescents with Down syndrome: evidence from a colour memory experiment
G Laws
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES (2002)
Genetic influences on brain structure
PM Thompson et al.
NATURE NEUROSCIENCE (2001)
Chromosomal variation in neurons of the developing and adult mammalian nervous system
SK Rehen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
From PREDs and open reading frames to cDNA isolation: Revisiting the human chromosome 21 transcription map
A Reymond et al.
GENOMICS (2001)
Evolutionary breakpoints on human chromosome 21
MT Davisson et al.
GENOMICS (2001)
Protein kinase Dyrk1 activates cAMP response element-binding protein during neuronal differentiation in hippocampal progenitor cells
EJ Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Neuroanatomy of Down's syndrome: A high-resolution MRI study
JD Pinter et al.
AMERICAN JOURNAL OF PSYCHIATRY (2001)
Failed retrograde transport of NGF in a mouse model of Down's syndrome: Reversal of cholinergic neurodegenerative phenotypes following NGF infusion
JD Cooper et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Murine models for Down syndrome
M Dierssen et al.
PHYSIOLOGY & BEHAVIOR (2001)
The effects of bilateral hippocampal damage on fMRI regional activations and interactions during memory retrieval
EA Maguire et al.
BRAIN (2001)
Mice containing a human chromosome 21 model behavioral impairment and cardiac anomalies of Down's syndrome
T Shinohara et al.
HUMAN MOLECULAR GENETICS (2001)
Amygdala and hippocampal volumes in children with Down syndrome: A high-resolution MRI study
JD Pinter et al.
NEUROLOGY (2001)
To ERR (meiotically) is human: The genesis of human aneuploidy
T Hassold et al.
NATURE REVIEWS GENETICS (2001)
On the cause of mental retardation in Down syndrome: extrapolation from full and segmental trisomy 16 mouse models
Z Galdzicki et al.
BRAIN RESEARCH REVIEWS (2001)
Tbx1 haploinsufficiency in the DiGeorge syndrome region causes aortic arch defects in mice
EA Lindsay et al.
NATURE (2001)
Ts65Dn mice, a model for Down syndrome, have deficits in context discrimination learning suggesting impaired hippocampal function
LA Hyde et al.
BEHAVIOURAL BRAIN RESEARCH (2001)
Germline transmission of a transferred human chromosome 21 fragment in transchromosomal mice
Y Kazuki et al.
JOURNAL OF HUMAN GENETICS (2001)
The mouse brain transcriptome by SAGE: Differences in gene expression between P30 brains of the partial trisomy 16 mouse model of Down syndrome (Ts65Dn) and normals
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GENOME RESEARCH (2000)
The 22q11 deletion syndromes
PJ Scambler
HUMAN MOLECULAR GENETICS (2000)
Intersectin 2, a new multimodular protein involved in clathrin-mediated endocytosis
C Pucharcos et al.
FEBS LETTERS (2000)
The DNA sequence of human chromosome 21
M Hattori et al.
NATURE (2000)
Synaptic deficit in the temporal cortex of partial trisomy 16 (Ts65Dn) mice
MA Kurt et al.
BRAIN RESEARCH (2000)
Combined ultrasound biometry, serum markers and age for Down syndrome risk estimation
RO Bahado-Singh et al.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY (2000)
Predicting language production in children and adolescents with Down syndrome: The role of comprehension
RS Chapman et al.
JOURNAL OF SPEECH LANGUAGE AND HEARING RESEARCH (2000)
Cerebellar and frontal lobe hypoplasia in fetuses with trisomy 21: Usefulness as combined US markers
TC Winter et al.
RADIOLOGY (2000)
Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome
ACE Granholm et al.
EXPERIMENTAL NEUROLOGY (2000)
Discovery and genetic localization of Down syndrome cerebellar phenotypes using the Ts65Dn mouse
LL Baxter et al.
HUMAN MOLECULAR GENETICS (2000)
Functional neuroanatomy of spatial working memory in children
CA Nelson et al.
DEVELOPMENTAL PSYCHOLOGY (2000)
The developmental cognitive neuroscience of language: A new research domain
AD Friederici
BRAIN AND LANGUAGE (2000)
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