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Adenovirus-mediated overexpression of diacylglycerol kinase-ζ inhibits endothelin-1-induced cardiomyocyte hypertrophy
H Takahashi et al.
CIRCULATION (2005)
Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells
M De Palma et al.
BLOOD (2005)
Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart
Z Wang et al.
NATURE BIOTECHNOLOGY (2005)
Large-scale molecular characterization of adeno-associated virus vector integration in mouse liver
H Nakai et al.
JOURNAL OF VIROLOGY (2005)
Hsp20, a novel α-crystallin, prevents Aβ fibril formation and toxicity
S Lee et al.
PROTEIN SCIENCE (2005)
S100A6 is a negative regulator of the induction of cardiac genes by trophic stimuli in cultured rat myocytes
JN Tsoporis et al.
EXPERIMENTAL CELL RESEARCH (2005)
PKC mediates cyclic stretch-induced cardiac hypertrophy through Rho family GTPases and mitogen-activated protein kinases in cardiomyocytes
J Pan et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2005)
Sarcomeric proteins and familial hypertrophic cardiomyopathy: Linking mutations in structural proteins to complex cardiovascular phenotypes
JC Tardiff
HEART FAILURE REVIEWS (2005)
Intracellular calcium release and cardiac disease
XHT Wehrens et al.
ANNUAL REVIEW OF PHYSIOLOGY (2005)
Efficient transduction of vascular endothelial cells with recombinant adeno-associated virus serotype 1 and 5 vectors
SF Chen et al.
HUMAN GENE THERAPY (2005)
In vivo and in vitro analysis of cardiac troponin I phosphorylation
S Sakthivel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Small heat shock protein with apparent molecular mass 20 kDa (Hsp20, HspB6) is not a genuine actin-binding protein
OV Bukach et al.
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY (2005)
Role of specific protein kinase C isoforms in modulation of beta(1)- and beta(2)-adrenergic receptors
J Guimond et al.
CELLULAR SIGNALLING (2005)
Serine 68 phosphorylation of phospholemman: acute isoforrn-specific activation of cardiac Na/K ATPase
BD Silverman et al.
CARDIOVASCULAR RESEARCH (2005)
Overexpression of sarcolipin decreases myocyte contractility and calcium transient
GJ Babu et al.
CARDIOVASCULAR RESEARCH (2005)
Unrestricted hepatocyte transduction with adeno-associated virus serotype 8 vectors in mice
H Nakai et al.
JOURNAL OF VIROLOGY (2005)
Over-expression of FK506-binding protein FKBP12.6 alters excitation-contraction coupling in adult rabbit cardiomyocytes
CM Loughrey et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
RACK1 regulates specific functions of Gβγ
SH Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Myocyte nitric oxide synthase 2 contributes to blunted β-adrenergic response in failing human hearts by decreasing Ca2+ transients
MT Ziolo et al.
CIRCULATION (2004)
Hydroporation as the mechanism of hydrodynamic delivery
G Zhang et al.
GENE THERAPY (2004)
Comparison of adenoviral and adeno-associated viral vectors for pancreatic gene delivery in vivo
AY Wang et al.
HUMAN GENE THERAPY (2004)
Successful gene transfer using adeno-associated virus vectors into the kidney: Comparison among adeno-associated virus serotype 1-5 vectors in vitro and in vivo
S Takeda et al.
NEPHRON EXPERIMENTAL NEPHROLOGY (2004)
Myofibrillogenesis in the developing chicken heart: Role of actin isoforms and of the pointed end actin capping protein tropomodulin during thin filament assembly
E Ehler et al.
DEVELOPMENTAL DYNAMICS (2004)
Modulation of in vivo cardiac function by myocyte-specific nitric oxide synthase-3
HC Champion et al.
CIRCULATION RESEARCH (2004)
Restoration of resting sarcomere length after uniaxial static strain is regulated by protein kinase Cε and focal adhesion kinase
H Mansour et al.
CIRCULATION RESEARCH (2004)
Abnormal calcium signaling and sudden cardiac death associated with mutation of calsequestrin
S Viatchenko-Karpinski et al.
CIRCULATION RESEARCH (2004)
PKC-α regulates cardiac contractility and propensity toward heart failure
JC Braz et al.
NATURE MEDICINE (2004)
Rapid uncoating of vector genomes is the key to efficient liver transduction with pseudotyped adeno-associated virus vectors
CE Thomas et al.
JOURNAL OF VIROLOGY (2004)
The giant protein titin - A major player in myocardial mechanics, signaling, and disease
HL Granzier et al.
CIRCULATION RESEARCH (2004)
Phosphoproteome analysis of cardiomyocytes subjected to β-adrenergic stimulation -: Identification and characterization of a cardiac heat shock protein p20
GX Chu et al.
CIRCULATION RESEARCH (2004)
Covalent and noncovalent modification of thin filament action - The essential role of troponin in cardiac muscle regulation
JM Metzger et al.
CIRCULATION RESEARCH (2004)
Adenovirus gene transfer of recombinant endothelial nitric oxide synthase enhances contractile function in ventricular myocytes
J Ren et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2004)
Mice overexpressing the cardiac sodium-calcium exchanger: defects in excitation-contraction coupling
H Reuter et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
Repeated adeno-associated virus serotype 2 aerosol-mediated cystic fibrosis transmembrane regulator gene transfer to the lungs of patients with cystic fibrosis - A multicenter, double-blind, placebo-controlled trial
RB Moss et al.
CHEST (2004)
Targeting neuronal nitric oxide synthase with gene transfer to modulate cardiac autonomic function
RM Mohan et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2004)
Sustained improvement of muscle function one year after full-length dystrophin gene transfer into mdx mice by a gutted helper-dependent adenoviral vector
RWR Dudley et al.
HUMAN GENE THERAPY (2004)
Effects of cardiomyopathic mutations on the biochemical and biophysical properties of the human α-tropomyosin
E Hilario et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2004)
Regulation of myocardial function by histidine-rich, calcium-binding protein
GC Fan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Functional adult myocardium in the absence of Na+-Ca2+ exchange -: Cardiac-specific knockout of NCX1
SA Henderson et al.
CIRCULATION RESEARCH (2004)
Inhibition of matrix metalloproteinase activity by TIMP-1 gene transfer effectively treats ischemic cardiomyopathy
V Jayasankar et al.
CIRCULATION (2004)
α-tropomyosin mutations Asp175Asn and Glu180Gly affect cardiac function in transgenic rats in different ways
D Wernicke et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2004)
A-kinase anchoring protein targeting of protein kinase A in the heart
ML Ruehr et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2004)
Therapeutic gene transfer to dystrophic diaphragm by an adenoviral vector deleted of all viral genes
S Matecki et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2004)
Safe two-plasmid production for the first clinical lentivirus vector that achieves >99% transduction in primary cells using a one-step protocol
XB Lu et al.
JOURNAL OF GENE MEDICINE (2004)
Thin filament-based modulation of contractile performance in human heart failure
T Noguchi et al.
CIRCULATION (2004)
Creation of a genetic calcium channel blocker by targeted gem gene transfer in the heart
M Murata et al.
CIRCULATION RESEARCH (2004)
G protein-coupled receptor-mediated phosphorylation of the activation loop of protein kinase D -: Dependence on plasma membrane translocation and protein kinase Cε
O Rey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Asymmetric septal hypertrophy in heterozygous cMyBP-C null mice
L Carrier et al.
CARDIOVASCULAR RESEARCH (2004)
Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system
C Burger et al.
MOLECULAR THERAPY (2004)
Molecular restoration of β-adrenergic receptor signaling improves contractile function of failing hearts
HT Tevaearai et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2004)
Parvalbumin gene delivery improves diastolic function in the aged myocardium in vivo
DE Michele et al.
MOLECULAR THERAPY (2004)
Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation
C Kupatt et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
Cellular and molecular aspects of familial hypertrophic cardiomyopathy caused by mutations in the cardiac troponin I gene
AV Gomes et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2004)
Role of troponin T in disease
AV Gomes et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2004)
Systemic delivery of genes to striated muscles using adeno-associated viral vectors
P Gregorevic et al.
NATURE MEDICINE (2004)
Impact of beta-myosin heavy chain expression on cardiac function during stress
M Krenz et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2004)
Distinctive activation mechanisms and functions for protein kinase Cδ
SF Steinberg
BIOCHEMICAL JOURNAL (2004)
Impaired regulation of neuronal nitric oxide synthase and heart rate during exercise in mice lacking one nNOS allele
EJF Danson et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
Intracoronary adenovirus encoding adenylyl cyclase VI increases left ventricular function in heart failure
NC Lai et al.
CIRCULATION (2004)
Depressed cardiac tension cost in experimental diabetes is due to altered myosin heavy chain isoform expression
VLM Rundell et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Indirect intracoronary delivery of adenovirus encoding adenylyl cyclase increases left ventricular contractile function in mice
DM Roth et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Modulation of cytosolic and intra-sarcoplasmic reticulum calcium waves by calsequestrin in rat cardiac myocytes
Z Kubalova et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
Differential cross-bridge kinetics of FHC myosin mutations R403Q and R453C in heterozygous mouse myocardium
BM Palmer et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
β2 Adrenoceptor gene therapy ameliorates left ventricular dysfunction following cardiac surgery
JM Jones et al.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2004)
Mild irritant prevents ethanol-induced gastric mucosal microcirculatory disturbances through actions of calcitonin gene-related peptide and PGI(2) in rats
T Saeki et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2004)
Genetic manipulation of myocardial β-adrenergic receptor activation and desensitization
JA Hata et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2004)
Protein kinase D is a novel mediator of cardiac troponin I phosphorylation and regulates myofilament function
RS Haworth et al.
CIRCULATION RESEARCH (2004)
Angiotensin II type 2 receptor gene transfer elicits cardioprotective effects in an angiotensin II infusion rat model of hypertension
BL Falcón et al.
PHYSIOLOGICAL GENOMICS (2004)
Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy
J Mogensen et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2004)
Age-dependent changes in contraction and regional myocardial myosin heavy chain isoform expression in rats
CA Carnes et al.
JOURNAL OF APPLIED PHYSIOLOGY (2004)
Cardiac-specific overexpression of sarcolipin inhibits sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA2a) activity and impairs cardiac function in mice
M Asahi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Inhibitory G protein overexpression provides physiologically relevant heart rate control in persistent atrial fibrillation
A Bauer et al.
CIRCULATION (2004)
Clinical and genetic characteristics of a cardiac actin gene mutations in hypertrophic cardiomyopathy
J Mogensen et al.
JOURNAL OF MEDICAL GENETICS (2004)
Small heat-shock protein Hsp20 phosphorylation inhibits β-agonist-induced cardiac apoptosis
GC Fan et al.
CIRCULATION RESEARCH (2004)
Gene transfer of parvalbumin improves diastolic dysfunction in senescent myocytes
F Huq et al.
CIRCULATION (2004)
Endothelial nitric oxide synthase overexpression attenuates myocardial reperfusion injury
SP Jones et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Adenovirus-mediated overexpression of inhibitor kappa B-alpha attenuates postinfarct remodeling in the rat heart
K Trescher et al.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2004)
Negatively charged self-assembling DNA/poloxamine nanospheres for in vivo gene transfer
B Pitard et al.
NUCLEIC ACIDS RESEARCH (2004)
FKBP12.6 overexpression decreases Ca2+ spark amplitude but enhances [Ca2+]i transient in rat cardiac myocytes
AM Gómez et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Safety and efficacy of factor IX gene transfer to skeletal muscle in murine and canine hemophilia B models by adeno-associated viral vector serotype 1
VR Arruda et al.
BLOOD (2004)
Comparative analysis of parvalbumin and SERCA2a cardiac myocyte gene transfer in a large animal model of diastolic dysfunction
JC Hirsch et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Clades of Adeno-associated viruses are widely disseminated in human tissues
GP Gao et al.
JOURNAL OF VIROLOGY (2004)
Functional diversity of protein phosphatase-1, a cellular economizer and reset button
H Ceulemans et al.
PHYSIOLOGICAL REVIEWS (2004)
Na+/Ca2+ exchanger overexpression impairs frequency- and ouabain-dependent cell shortening in adult rat cardiomyocytes
B Bölck et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Cardiac myosin binding protein C - Its role in physiology and disease
E Flashman et al.
CIRCULATION RESEARCH (2004)
Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5
RB Vega et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Efficient transduction of skeletal muscle using vectors based on adeno-associated virus serotype 6
MJ Blankinship et al.
MOLECULAR THERAPY (2004)
Cytoskeletal modulation of electrical and mechanical activity in cardiac myocytes
SC Calaghan et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2004)
Parvalbumin corrects slowed relaxation in adult cardiac myocytes expressing hypertrophic cardiomyopathy-linked α-tropomyosin mutations
P Coutu et al.
CIRCULATION RESEARCH (2004)
Cardiomyocyte-specific overexpression of nitric oxide synthase 3 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction
S Janssens et al.
CIRCULATION RESEARCH (2004)
Mutation of the slow myosin heavy chain rod domain underlies hyaline body myopathy
S Bohlega et al.
NEUROLOGY (2004)
Nitroprusside increases gene transfer associated with intracoronary delivery of adenovirus
DM Roth et al.
HUMAN GENE THERAPY (2004)
Structural based insights into the role of troponin in cardiac muscle pathophysiology
MX Li et al.
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY (2004)
Mutations in the slow skeletal muscle fiber myosin heavy chain gene (MYH7) cause laing early-onset distal myopathy (MPD1)
C Meredith et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2004)
S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature)
I Marenholz et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Cross-dressing the virion: the transcapsidation of adeno-associated virus serotypes functionally defines subgroups
JE Rabinowitz et al.
JOURNAL OF VIROLOGY (2004)
Characterization of recombinant skeletal muscle (Ser-2843) and cardiac muscle (Ser-2809) ryanodine receptor phosphorylation mutants
M Stange et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality
KL Fritz-Six et al.
JOURNAL OF CELL BIOLOGY (2003)
Cardiac SR-coupled PP1 activity and expression are increased and inhibitor 1 protein expression is decreased in failing hearts
RC Gupta et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2003)
Self-complementary adeno-associated virus serotype 2 vector: Global distribution and broad dispersion of AAV-mediated transgene expression in mouse brain
HY Fu et al.
MOLECULAR THERAPY (2003)
Inhibitory G-proteins and their role in desensitization of the adenylyl cyclase pathway in heart failure
A El-Armouche et al.
CARDIOVASCULAR RESEARCH (2003)
C-terminal truncation of cardiac troponin I causes divergent effects on ATPase and force - Implications for the pathophysiology of myocardial stunning
DB Foster et al.
CIRCULATION RESEARCH (2003)
What is the role of β-adrenergic signaling in heart failure?
MJ Lohse et al.
CIRCULATION RESEARCH (2003)
Inhibition of δ-protein kinase C protects against reperfusion injury of the ischemic heart in vivo
K Inagaki et al.
CIRCULATION (2003)
Dynamic regulation of sodium/calcium exchange function in human heart failure
CR Weber et al.
CIRCULATION (2003)
Tropomodulins: life at the slow end
RS Fischer et al.
TRENDS IN CELL BIOLOGY (2003)
Cardiomyopathic tropomyosin mutations that increase thin filament Ca2+ sensitivity and tropomyosin N-domain flexibility
MJ Heller et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
S Hacein-Bey-Abina et al.
SCIENCE (2003)
Myosin storage myopathy associated with a heterozygous missense mutation in MYH7
H Tajsharghi et al.
ANNALS OF NEUROLOGY (2003)
Microdystrophin gene therapy of cardiomyopathy restores dystrophin-glycoprotein complex and improves sarcolemma integrity in the mdx mouse heart
YP Yue et al.
CIRCULATION (2003)
Calsequestrin determines the functional size and stability of cardiac intracellular calcium stores:: Mechanism for hereditary arrhythmia
D Terentyev et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Role of antisense RNA in coordinating cardiac myosin heavy chain gene switching
F Haddad et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Sorcin inhibits calcium release and modulates excitation-contraction coupling in the heart
EF Farrell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Transgenic overexpression of the Ca2+-binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performance
P Most et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Role of troponin I phosphorylation in protein kinase C-mediated enhanced contractile performance of rat myocytes
MV Westfall et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
SE Raper et al.
MOLECULAR GENETICS AND METABOLISM (2003)
A mouse model of familial hypertrophic cardiomyopathy caused by a α-tropomyosin mutation
R Prabhakar et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2003)
Adenovirus-mediated gene transfer to adult mouse cardiomyocytes is selectively influenced by culture medium
ZB Li et al.
JOURNAL OF GENE MEDICINE (2003)
Contractile effects of adenovirally-mediated increases in SERCA2a activity: A comparison between adult rat and rabbit ventricular myocytes
B Chaudhri et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2003)
Additive protection of the ischemic heart ex vivo by combined treatment with δ-protein kinase C inhibitor and ε-protein kinase C activator
K Inagaki et al.
CIRCULATION (2003)
Recombinant AAV serotype 1 transduction efficiency and tropism in the murine brain
C Wang et al.
GENE THERAPY (2003)
Transgenic rat hearts overexpressing SERCA2a show improved contractility under baseline conditions and pressure overload
OJ Müller et al.
CARDIOVASCULAR RESEARCH (2003)
Sorcin regulates excitation-contraction coupling in the heart
MB Meyers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Effects of two Gβγ-binding proteins -: N-terminally truncated phosducin and β-adrenergic receptor kinase C terminus (βARKct) -: in heart failure
Z Li et al.
GENE THERAPY (2003)
Effects of adenovirus-mediated sorcin overexpression on excitation-contraction coupling in isolated rabbit cardiomyocytes
T Seidler et al.
CIRCULATION RESEARCH (2003)
Information transfer in the penta-EF-hand protein sorcin does not operate via the canonical structural/functional pairing - A study with site-specific mutants
M Mella et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Structure of the core domain of human cardiac troponin in the Ca2+-saturated form
S Takeda et al.
NATURE (2003)
Cardiac excitation-contraction coupling in the absence of Na+-Ca2+ exchange
H Reuter et al.
CELL CALCIUM (2003)
Isoenzyme-selective regulation of SERCA2 gene expression by protein kinase C in neonatal rat ventricular myocytes
MJ Porter et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
Role of phosphoinositide 3-kinase in cardiac function and heart failure
SVN Prasad et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2003)
AAV serotype 2 vectors preferentially integrate into active genes in mice
H Nakai et al.
NATURE GENETICS (2003)
Nebulin: The nebulous, multifunctional giant of striated muscle
AS McElhinny et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2003)
Phospholamban: A crucial regulator of cardiac contractility
DH MacLennan et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
The MKK6-p38 MAPK pathway prolongs the cardiac contractile calcium transient, downregulates SERCA2, and activates NF-AT
C Andrews et al.
CARDIOVASCULAR RESEARCH (2003)
Ca2+-dependent interaction of S100A1 with the sarcoplasmic reticulum Ca2+-ATPase2a and phospholamban in the human heart
R Kiewitz et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death
XHT Wehrens et al.
CELL (2003)
Cdc42 plays a critical role in assembly of sarcomere units in series of cardiac myocytes
T Nagai et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Recombinant adeno-associated virus serotype 4 mediates unique and exclusive long-term transduction of retinal pigmented epithelium in rat, dog, and nonhuman primate after subretinal delivery
M Weber et al.
MOLECULAR THERAPY (2003)
Prolonged dystrophin expression and functional correction of mdx mouse muscle following gene transfer with a helper-dependent (gutted) adenovirus-encoding murine dystrophin
R Gilbert et al.
HUMAN MOLECULAR GENETICS (2003)
β-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure
S Reiken et al.
CIRCULATION (2003)
Multiply attenuated, self-inactivating lentiviral vectors efficiently deliver and express genes for extended periods of time in adult rat cardiomyocytes in vivo
S Fleury et al.
CIRCULATION (2003)
Analysis of myosin heavy chain functionality in the heart
M Krenz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Conditional expression of SV40 T-antigen in mouse cardiomyocytes facilitates an inducible switch from proliferation to differentiation
II Rybkin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mitogen-activated protein kinases:: A new therapeutic target in cardiac pathology
T Ravingerová et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2003)
Regulation of sarco(endo)plasmic reticulum Ca2+ adenosine triphosphatase by phospholamban and sarcolipin:: Implication for cardiac hypertrophy and failure
M Asahi et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2003)
Cardiomyopathic features associated with muscular dystrophy are independent of dystrophin absence in cardiovasculature
TA Hainsey et al.
NEUROMUSCULAR DISORDERS (2003)
E-Tmod capping of actin filaments at the slow-growing end is required to establish mouse embryonic circulation
X Chu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2003)
Multigene adenoviral therapy for the attenuation of ischemia-reperfusion injury after preservation for cardiac transplantation
HJ Abunasra et al.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2003)
Costameres: The Achilles' heel of herculean muscle
JM Ervasti
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Gene therapy with inducible nitric oxide synthase protects against myocardial infarction via a cyclooxygenase-2-dependent mechanism
QH Li et al.
CIRCULATION RESEARCH (2003)
Cross-regulation of novel protein kinase C (PKC) isoform function in cardiomyocytes -: Role of PKCε in activation loop phosphorylations and PKCδ in hydrophobic motif phosphorylations
VO Rybin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B
CS Manno et al.
BLOOD (2003)
Cellular basis of abnormal calcium transients of failing human ventricular myocytes
V Piacentino et al.
CIRCULATION RESEARCH (2003)
Lateral force transmission across costameres in skeletal muscle
RJ Bloch et al.
EXERCISE AND SPORT SCIENCES REVIEWS (2003)
'Advanced' generation lentivirruses as efficient vectors for cardiomyocyte gene transduction in vitro and in vivo
D Bonci et al.
GENE THERAPY (2003)
The protective effect of cardiac gene transfer of CuZn-sod in comparison with the cardioprotector monohydroxyethylrutoside against doxorubicin-induced cardiotoxicity in cultured cells
MAIA El Hassan et al.
CANCER GENE THERAPY (2003)
Phosphorylation or glutamic acid substitution at protein kinase C sites on cardiac troponin I differentially depress myofilament tension and shortening velocity
EM Burkart et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The functional effect of adenoviral Na+/Ca2+ exchanger overexpression in rabbit myocytes depends on the activity of the Na+/K+-ATPase
W Schillinger et al.
CARDIOVASCULAR RESEARCH (2003)
[Na+]i handling in the failing human heart
B Pieske et al.
CARDIOVASCULAR RESEARCH (2003)
Retroviral vector integration occurs in preferred genomic targets of human bone marrow-repopulating cells
S Laufs et al.
BLOOD (2003)
Intracellular Na+ regulation in cardiac myocytes
DM Bers et al.
CARDIOVASCULAR RESEARCH (2003)
Atrial chamber-specific expression of sarcolipin is regulated during development and hypertrophic remodeling
S Minamisawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Endothelial nitric-oxide synthase enhances lipopolysaccharide-stimulated tumor necrosis factor-α expression via cAMP-mediated p38 MAPK pathway in cardiomyocytes
TQ Peng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Decreased efficiency of adenovirus-mediated gene transfer in aging cardiomyocytes
C Communal et al.
CIRCULATION (2003)
Utility of genetic screening in hypertrophic cardiomyopathy:: Prevalence and significance of novel and double (homozygous and heterozygous) β-myosin mutations
SA Mohiddin et al.
GENETIC TESTING (2003)
Cardiac assessment in childhood carriers of Duchenne and Becker muscular dystrophies
MA Nolan et al.
NEUROMUSCULAR DISORDERS (2003)
Overexpression of eNOS in RVLM improves impaired baroreflex control of heart rate in SHRSP
T Kishi et al.
HYPERTENSION (2003)
Acute effects of desmin mutations on cytoskeletal and cellular integrity in cardiac myocytes
K Haubold et al.
CELL MOTILITY AND THE CYTOSKELETON (2003)
Targeting diastolic dysfunction by genetic engineering of calcium handling proteins
P Coutu et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2003)
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
S Hacein-Bey-Abina et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Idiopathic restrictive cardiomyopathy is part of the clinical expression of cardiac troponin I mutations
J Mogensen et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Alterations in protein kinase C isoenzyme expression and autophosphorylation during the progression of pressure overload-induced left ventricular hypertrophy
AL Bayer et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2003)
Phospholemman modulates Na+/Ca2+ exchange in adult rat cardiac myocytes
XQ Zhang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2003)
Phenotypic consequences of beta(1)-tubulin expression and MAP4 decoration of microtubules in adult cardiocytes
M Takahashi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2003)
Helper-independent and AAV-ITR-independent chromosomal integration of double-stranded linear DNA vectors in mice
H Nakai et al.
MOLECULAR THERAPY (2003)
The heart in human dystrophinopathies
J Finsterer et al.
CARDIOLOGY (2003)
Prolonged survival of heart allografts transduced with AAV-CTLA4IG
ZY Chen et al.
MICROSURGERY (2003)
Nonviral gene gun mediated transfer into the beating heart
Y Matsuno et al.
ASAIO JOURNAL (2003)
Adeno-associated virus type 5: Transduction efficiency and cell-type specificity in the primate retina
AJ Lotery et al.
HUMAN GENE THERAPY (2003)
Requirement of nuclear factor of activated T-cells in calcineurin-mediated cardiomyocyte hypertrophy
E van Rooij et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Efficient gene transfer into the CNS by lentiviral vectors purified by anion exchange chromatography
M Scherr et al.
GENE THERAPY (2002)
A novel muscle-specific enhancer identified within the deletion overlap region of two XLDC patients lacking muscle exon 1 of the human dystrophin gene
C Bastianutto et al.
GENOMICS (2002)
Adenovirus and adeno-associated virus vectors
CM Lai et al.
DNA AND CELL BIOLOGY (2002)
Skeletal muscle of mice with a mutation in slow α-tropomyosin is weaker at lower lengths
A de Haan et al.
NEUROMUSCULAR DISORDERS (2002)
Abnormal Ca2+ release, but normal ryanodine receptors, in canine and human heart failure
MT Jiang et al.
CIRCULATION RESEARCH (2002)
Structures, functions and molecular evolution of the penta-EF-hand Ca2+-binding proteins
M Maki et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2002)
Desmin cytoskeleton: A potential regulator of muscle mitochondrial behavior and function
Y Capetanaki
TRENDS IN CARDIOVASCULAR MEDICINE (2002)
Gene gun-mediated CTLA4Ig-gene transfer for modification of allogeneic cardiac grafts
Y Umeda et al.
TRANSPLANTATION PROCEEDINGS (2002)
Insect cells as a factory to produce adeno-associated virus type 2 vectors
M Urabe et al.
HUMAN GENE THERAPY (2002)
c-Jun N-terminal kinase activation mediates downregulation of connexin43 in cardiomyocytes
BG Petrich et al.
CIRCULATION RESEARCH (2002)
Effects of Na+/Ca2+ exchanger downregulation on contractility and [Ca2+]i transients in adult rat myocytes
GM Tadros et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2002)
Cardiovascular and metabolic alterations in mice lacking β1- and β2-adrenergic receptors
D Bernstein
TRENDS IN CARDIOVASCULAR MEDICINE (2002)
Molecular mechanisms of inherited cardiomyopathies
D Fatkin et al.
PHYSIOLOGICAL REVIEWS (2002)
Functional correction of adult mdx mouse muscle using gutted adenoviral vectors expressing full-length dystrophin
C DelloRusso et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Single mutation (A162H) in human cardiac troponin I corrects acid pH sensitivity of Ca2+-regulated actomyosin S1 ATPase
R Dargis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Myofilament calcium sensitivity and cardiac disease - Insights from troponin I isoforms and mutants
MV Westfall et al.
CIRCULATION RESEARCH (2002)
Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy
GP Gao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Lentiviral vectors for delivery of genes into neonatal and adult ventricular cardiac myocytes in vitro and in vivo
J Zhao et al.
BASIC RESEARCH IN CARDIOLOGY (2002)
A nonionic amphiphile agent promotes gene delivery in vivo to skeletal and cardiac muscles
B Pitard et al.
HUMAN GENE THERAPY (2002)
Gutted adenoviral vector growth using E1/E2b/E3-deleted helper viruses
C Barjot et al.
JOURNAL OF GENE MEDICINE (2002)
Physiological and morphological effects of alendronate on rabbit esophageal epithelium
A Dobrucali et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2002)
Delivery of α- and β-sarcoglycan by recombinant adeno-associated virus:: Efficient rescue of muscle, but differential toxicity
D Dressman et al.
HUMAN GENE THERAPY (2002)
Phospholemman (FXYD1) associates with Na,K-ATPase and regulates its transport properties
G Crambert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Expression of cyclin D1 and CDK4 causes hypertrophic growth of cardiomyocytes in culture: a possible implication for cardiac hypertrophy
M Tamamori-Adachi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Cardiac dysfunction in hypertrophic cardiomyopathy mutant tropomyosin mice is transgene-dependent, hypertrophy-independent, and improved by β-blockade
DE Michele et al.
CIRCULATION RESEARCH (2002)
A mitogen-activated protein kinase is involved in the inotropic but not chronotropic actions of adrenoceptor agonists and endothelin-1
SLM Peters et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2002)
Calcium, calmodulin, and calcium-calmodulin kinase II: Heartbeat to heartbeat and beyond
LS Maier et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2002)
Intracellular β-blockade:: overexpression of Gαi2 depresses the β-adrenergic response in intact myocardium
PML Janssen et al.
CARDIOVASCULAR RESEARCH (2002)
Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery
M Hoshijima et al.
NATURE MEDICINE (2002)
Calcium cycling in congestive heart failure
G Hasenfuss et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2002)
Sarcolipin inhibits polymerization of phospholamban to induce superinhibition of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs)
M Asahi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Knockout mice for pharmacological screening testing the specificity of Na+-Ca2+ exchange inhibitors
H Reuter et al.
CIRCULATION RESEARCH (2002)
Myocardial gene transfer and overexpression of β2-adrenergic receptors potentiates the functional recovery of unloaded failing hearts
HT Tevaearai et al.
CIRCULATION (2002)
Global cardiac-specific transgene expression using cardiopulmonary bypass with cardiac isolation
CR Bridges et al.
ANNALS OF THORACIC SURGERY (2002)
Overexpression of SERCA2a accelerates repolarisation in rabbit ventricular myocytes
CMN Terracciano et al.
CELL CALCIUM (2002)
α-Adrenergic response and myofilament activity in mouse hearts lacking PKC phosphorylation sites on cardiac TnI
DE Montgomery et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2002)
Inhibition of βARK1 restores impaired biochemical β-adrenergic receptor responsiveness but does not rescue CREBA133 induced cardiomyopathy
AD Eckhart et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2002)
Micro-dystrophin cDNA ameliorates dystrophic phenotypes when introduced into mdx mice as a transgene
M Sakamoto et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Divergent abnormal muscle relaxation by hypertrophic cardiomyopathy and nemaline myopathy mutant tropomyosins
DE Michele et al.
PHYSIOLOGICAL GENOMICS (2002)
Adenoviral gene transfer to the heart during cardiopulmonary bypass: effect of myocardial protection technique on transgene expression
JM Jones et al.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2002)
Optimal range for parvalbumin as relaxing agent in adult cardiac myocytes: Gene transfer and mathematical modeling
P Coutu et al.
BIOPHYSICAL JOURNAL (2002)
Phosphorylation of troponin I controls cardiac twitch dynamics - Evidence from phosphorylation site mutants expressed on a troponin I-null background in mice
YQ Pi et al.
CIRCULATION RESEARCH (2002)
Effects of Na+/Ca2+-exchanger overexpression on excitation-contraction coupling in adult rabbit ventricular myocytes
HK Ranu et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2002)
Enhancement of L-type Ca2+ current from neonatal mouse ventricular myocytes by constitutively active PKC-βII
KJ Alden et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2002)
Adeno-associated virus vector gene transfer and sarcolemmal expression of a 144 kDa micro-dystrophin effectively restores the dystrophin-associated protein complex and inhibits myofibre degeneration in nude/mdx mice
SA Fabb et al.
HUMAN MOLECULAR GENETICS (2002)
Impaired cardiac contractility response to hemodynamic stress in S100A1-deficient mice
XJ Du et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion -: The roles of PI3-kinase, akt, and endothelial nitric oxide synthase phosphorylation
F Gao et al.
CIRCULATION (2002)
Hypertrophic cardiomyopathy in cardiac myosin binding protein-C knockout mice
SP Harris et al.
CIRCULATION RESEARCH (2002)
PKCα regulates the hypertrophic growth of cardiomyocytes through extracellular signal-regulated kinase1/2 (ERK1/2)
JC Braz et al.
JOURNAL OF CELL BIOLOGY (2002)
Targeting phospholamban by gene transfer in human heart failure
F del Monte et al.
CIRCULATION (2002)
The Na+-Ca2+ exchanger cardiac is essential for the action of glycosides
H Reuter et al.
CIRCULATION RESEARCH (2002)
Intracellular [Na+] and Na+ pump rate in rat and rabbit ventricular myocytes
S Despa et al.
JOURNAL OF PHYSIOLOGY-LONDON (2002)
p38 mitogen-activated protein kinase mediates a negative inotropic effect in cardiac myocytes
P Liao et al.
CIRCULATION RESEARCH (2002)
Old and new tools to dissect calcineurin's role in pressure-overload cardiac hypertrophy
WG Zhang
CARDIOVASCULAR RESEARCH (2002)
Cardiovascular effects of overexpression of endothelial nitric oxide synthase in the rostral ventrolateral medulla in stroke-prone spontaneously hypertensive rats
T Kishi et al.
HYPERTENSION (2002)
Enhancement of phosphatidylcholine biosynthesis by angiotensin-(1-7) in the rat renal cortex
MM Gironacci et al.
BIOCHEMICAL PHARMACOLOGY (2002)
Restoration of deficient membrane proteins in the cardiomyopathic hamster by in vivo cardiac gene transfer
Y Ikeda et al.
CIRCULATION (2002)
Rescue of hereditary form of dilated cardiomyopathy by rAAV-mediated somatic gene therapy: Amelioration of morphological findings, sarcolemmal permeability, cardiac performances, and the prognosis of TO-2 hamsters
T Kawada et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Seven-transmembrane-spanning receptors and heart function
HA Rockman et al.
NATURE (2002)
Expression of a beta-adrenergic receptor kinase inhibitor reverses dysfunction in failing cardiomyocytes
AD Eckhart et al.
MOLECULAR THERAPY (2002)
Altered Na/Ca exchange activity in cardiac hypertrophy and heart failure: a new target for therapy?
KR Sipido et al.
CARDIOVASCULAR RESEARCH (2002)
Modular flexibility of dystrophin: Implications for gene therapy of Duchenne muscular dystrophy
SQ Harper et al.
NATURE MEDICINE (2002)
Myocardial contractile function and heart rate in mice with myocyte-specific overexpression of endothelial nitric oxide synthase
F Brunner et al.
CIRCULATION (2001)
Power output is increased after phosphorylation of myofibrillar proteins in rat skinned cardiac myocytes
TJ Herron et al.
CIRCULATION RESEARCH (2001)
Frequency and clinical characteristics of dilated cardiomyopathy caused by desmin gene mutation in a Japanese population
Y Miyamoto et al.
EUROPEAN HEART JOURNAL (2001)
Immune evasion by muscle-specific gene expression in dystrophic muscle
D Hartigan-O'Connor et al.
MOLECULAR THERAPY (2001)
The complete gene sequence of titin, expression of an unusual ≈700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system
ML Bang et al.
CIRCULATION RESEARCH (2001)
S100A1:: A regulator of myocardial contractility
P Most et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Differential activation of mitogen-activated protein kinase cascades and apoptosis by protein kinase C ε and δ in neonatal rat ventricular myocytes
MC Heidkamp et al.
CIRCULATION RESEARCH (2001)
Expression of slow skeletal troponin I in adult transgenic mouse heart muscle reduces the force decline observed during acidic conditions
BM Wolska et al.
JOURNAL OF PHYSIOLOGY-LONDON (2001)
Cardioprotective function of inducible nitric oxide synthase and role of nitric oxide in myocardial ischemia and preconditioning: an overview of a decade of research
R Bolli
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2001)
Dystrophin muscle enhancer 1 is implicated in the activation of non-muscle isoforms in the skeletal muscle of patients with X-linked dilated cardiomyopathy
C Bastianutto et al.
HUMAN MOLECULAR GENETICS (2001)
Ventricular dysfunction after cardioplegic arrest is improved after myocardial gene transfer of a β-adrenergic receptor kinase inhibitor
HT Tevaearai et al.
CIRCULATION (2001)
Evidence for selective coupling of α1-adrenergic receptors to phospholipase C-β1 in rat neonatal cardiomyocytes
JF Arthur et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Titin-actin interaction in mouse myocardium:: Passive tension modulation and its regulation by calcium/S100A1
R Yamasaki et al.
BIOPHYSICAL JOURNAL (2001)
Adaptor proteins in protein kinase C-mediated signal transduction
D Schechtman et al.
ONCOGENE (2001)
A familial hypertrophic cardiomyopathy α-tropomyosin mutation causes severe cardiac hypertrophy and death in mice
R Prabhakar et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2001)
Dystrophin expression in muscle following gene transfer with a fully deleted (gutted') adenovirus is markedly improved by trans-acting adenoviral gene products
R Gilbert et al.
HUMAN GENE THERAPY (2001)
Improvement in survival and cardiac metabolism after gene transfer of sarcoplasmic reticulum Ca2+-ATPase in a rat model of heart failure
F del Monte et al.
CIRCULATION (2001)
A novel method using baculovirus-mediated gene transfer for production of recombinant adeno-associated virus vectors
K Sollerbrant et al.
JOURNAL OF GENERAL VIROLOGY (2001)
How to optimize in vivo gene transfer to cardiac myocytes:: Mechanical or pharmacological procedures?
D Logeart et al.
HUMAN GENE THERAPY (2001)
Loaded shortening and power output in cardiac myocytes are dependent on myosin heavy chain isoform expression
TJ Herron et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2001)
Hsp90 ensures the transition from the early Ca2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells
A Brouet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Cardiac gap junction channels: modulation of expression and channel properties
TAB van Veen et al.
CARDIOVASCULAR RESEARCH (2001)
Transgenic mice with cardiac-specific expression of activating transcription factor 3, a stress-inducible gene, have conduction abnormalities and contractile dysfunction
Y Okamoto et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
Adeno-associated virus type 6 (AAV6) vectors mediate efficient transduction of airway epithelial cells in mouse lungs compared to that of AAV2 vectors
CL Halbert et al.
JOURNAL OF VIROLOGY (2001)
Efficacy of adenoviral gene transfer with manganese superoxide dismutase and endothelial nitric oxide synthase in reducing ischemia and reperfusion injury
HJ Abunasra et al.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2001)
Overexpression of γ-sarcoglycan induces severe muscular dystrophy -: Implications for the regulation of sarcoglycan assembly
XL Zhu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Overwhelming evidence of the beneficial effects of SERCA gene transfer in heart failure
F del Monte et al.
CIRCULATION RESEARCH (2001)
Morphological and physiological restorations of hereditary form of dilated cardiomyopathy by somatic gene therapy
T Kawada et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
SERCA pump level is a critical determinant of Ca2+ homeostasis and cardiac contractility
M Periasamy et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2001)
Increased basal contractility of cardiomyocytes overexpressing protein kinase Cε and blunted positive inotropic response to endothelin-1
S Baudet et al.
CARDIOVASCULAR RESEARCH (2001)
Actin dynamics at pointed ends regulates thin filament length in striated muscle
R Littlefield et al.
NATURE CELL BIOLOGY (2001)
Nemaline myopathy caused by mutations in the muscle α-skeletal-actin gene
B Ilkovski et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2001)
Phosphorylation of troponin I by protein kinase A accelerates relaxation and crossbridge cycle kinetics in mouse ventricular muscle
JC Kentish et al.
CIRCULATION RESEARCH (2001)
Cardiac βARK1 inhibition prolongs survival and augments β blocker therapy in a mouse model of severe heart failure
VB Harding et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Activation of cardiac c-Jun NH2-terminal kinases and p38-mitogen-activated protein kinases with abrupt changes in hemodynamic load
TA Fischer et al.
HYPERTENSION (2001)
SERCA2a overexpression decreases the incidence of aftercontractions in adult rabbit ventricular myocytes
K Davia et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2001)
Gene transfer of heterologous G protein-coupled receptors to cardiomyocytes -: Differential effects on contractility
KL Laugwitz et al.
CIRCULATION RESEARCH (2001)
Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo
LJ De Windt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
FKBP binding characteristics of cardiac microsomes from diverse vertebrates
LH Jeyakumar et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Cardiac abnormalities and skeletal muscle weakness in carriers of Duchenne and Becker muscular dystrophies and controls
L Grain et al.
NEUROMUSCULAR DISORDERS (2001)
The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms
JG Seidman et al.
CELL (2001)
AKAP-mediated targeting of protein kinase A regulates contractility in cardiac myocytes
MA Fink et al.
CIRCULATION RESEARCH (2001)
A mutation in α-tropomyosinslow affects muscle strength, maturation and hypertrophy in a mouse model for nemaline myopathy
MA Corbett et al.
HUMAN MOLECULAR GENETICS (2001)
Dual modulation of cell survival and cell death by β2-adrenergic signaling in adult mouse cardiac myocytes
WZ Zhu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Cardiac hypertrophy and impaired relaxation in transgenic mice overexpressing triadin 1
U Kirchhefer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Structural alterations in cardiac calcium release units resulting from overexpression of junctin
L Zhang et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2001)
Nonviral gene gun-mediated CTLA4-Ig gene transfer for modification of donor organs
Y Umeda et al.
TRANSPLANTATION PROCEEDINGS (2001)
Transgenic mouse models of angiotensin receptor subtype function in the cardiovascular system
M Brede et al.
REGULATORY PEPTIDES (2001)
The dual-specificity phosphatase MKP-1 limits the cardiac hypertrophic response in vitro and in vivo
OF Bueno et al.
CIRCULATION RESEARCH (2001)
Overexpression of the Na+/Ca2+ exchanger and inhibition of the sarcoplasmic reticulum Ca2+-ATPase in ventricular myocytes from transgenic mice
CMN Terracciano et al.
CARDIOVASCULAR RESEARCH (2001)
In vivo acceleration of heart relaxation performance by parvalbumin gene delivery
ML Szatkowski et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Manipulating the contractile apparatus: Genetically defined animal models of cardiovascular disease
F Dalloz et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2001)
Tibialis anterior muscles in mdx mice are highly susceptible to contraction-induced injury
C Dellorusso et al.
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY (2001)
Protein kinase c-epsilon mediates phorbol ester-induced phosphorylation of connexin-43
BW Doble et al.
CELL COMMUNICATION AND ADHESION (2001)
β2-adrenergic receptor-induced p38 MAPK activation is mediated by protein kinase A rather than by Gi or Gβγ in adult mouse cardiomyocytes
M Zheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Adeno-associated virus vector carrying human minidystrophin genes effectively ameliorates muscular dystrophy in mdx mouse model
B Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Direct intra-cardiomuscular transfer of β2-adrenergic receptor gene augments cardiac output in cardiomyopathic hamsters
K Tomiyasu et al.
GENE THERAPY (2000)
Overexpression of eNOS in NTS causes hypotension and bradycardia in vivo
K Sakai et al.
HYPERTENSION (2000)
Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors
HJ Chao et al.
MOLECULAR THERAPY (2000)
Targeted disruption of Na+/Ca2+ exchanger gene leads to cardiomyocyte apoptosis and defects in heartbeat
K Wakimoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Intracoronary delivery of adenovirus encoding adenylyl cyclase VT increases left ventricular function and cAMP-generating capacity
NC Lai et al.
CIRCULATION (2000)
Blocking free radical production via adenoviral gene transfer decreases cardiac ischemia-reperfusion injury
HL Zhu et al.
MOLECULAR THERAPY (2000)
Pretreatment with protease is a useful experimental strategy for enhancing adenovirus-mediated cancer gene therapy
N Kuriyama et al.
HUMAN GENE THERAPY (2000)
Dynamics of actin and α-actinin in nascent myofibrils and stress fibers
F Hasebe-Kishi et al.
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY (2000)
Altered hemodynamics in transgenic mice harboring mutant tropomyosin linked to hypertrophic cardiomyopathy
CC Evans et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2000)
Transgenic modeling of a cardiac troponin I mutation linked to familial hypertrophic cardiomyopathy
J James et al.
CIRCULATION RESEARCH (2000)
In vivo gene gun-mediated transduction into rat heart with Epstein-Barr virus-based episomal vectors
K Nishizaki et al.
ANNALS OF THORACIC SURGERY (2000)
Impaired contractile performance of cultured rabbit ventricular myocytes after adenoviral gene transfer of Na+-Ca2+ exchanger
W Schillinger et al.
CIRCULATION RESEARCH (2000)
Assembly of the dystrophin-associated protein complex does not require the dystrophin COOH-terminal domain
GE Crawford et al.
JOURNAL OF CELL BIOLOGY (2000)
Transduction of murine cerebellar neurons with recombinant FIV and AAV5 vectors
JM Alisky et al.
NEUROREPORT (2000)
The FXYD gene family of small ion transport regulators or channels: cDNA sequence, protein signature sequence, and expression
KJ Sweadner et al.
GENOMICS (2000)
Molecular and genetic characterization of sarcospan:: insights into sarcoglycan-sarcospan interactions
RH Crosbie et al.
HUMAN MOLECULAR GENETICS (2000)
Early adenovirus-mediated gene transfer effectively prevents muscular dystrophy in alpha-sarcoglycan-deficient mice
V Allamand et al.
GENE THERAPY (2000)
Application of cDNA microarrays in determining molecular phenotype in cardiac growth, development, and response to injury
PD Sehl et al.
CIRCULATION (2000)
PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts
SO Marx et al.
CELL (2000)
Adenovirus-based phospholamban antisense expression as a novel approach to improve cardiac contractile dysfunction - Comparison of a constitutive viral versus an endothelin-1-responsive cardiac promoter
K Eizema et al.
CIRCULATION (2000)
Preservation of myocardial β-adrenergic receptor signaling delays the development of heart failure after myocardial infarction
DC White et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Single-molecule mechanics of R403Q cardiac myosin isolated from the mouse model of familial hypertrophic cardiomyopathy
MJ Tyska et al.
CIRCULATION RESEARCH (2000)
The way things move: Looking under the hood of molecular motor proteins
RD Vale et al.
SCIENCE (2000)
Enhanced cardiac contractility after gene transfer of V2 vasopressin receptors in vivo by ultrasound-guided injection or transcoronary delivery
HJ Weig et al.
CIRCULATION (2000)
Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer
J Zabner et al.
JOURNAL OF VIROLOGY (2000)
Highly efficient adenovirus-mediated gene transfer to cardiac myocytes after single-pass coronary delivery
D Logeart et al.
HUMAN GENE THERAPY (2000)
Cardiac troponin I inhibitory peptide: location of interaction sites on troponin C
MB Abbott et al.
FEBS LETTERS (2000)
Myosin heavy chain isoform expression in the failing and nonfailing human heart
S Miyata et al.
CIRCULATION RESEARCH (2000)
Chimera analysis of troponin I domains that influence Ca2+-activated myofilament tension in adult cardiac myocytes
MV Westfall et al.
CIRCULATION RESEARCH (2000)
Restoration of diastolic function in senescent rat hearts through adenoviral gene transfer of sarcoplasmic reticulum Ca2+-ATPase
U Schmidt et al.
CIRCULATION (2000)
Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo - An apoptosis-independent model of dilated heart failure
LJ De Windt et al.
CIRCULATION RESEARCH (2000)
Expression of the β (slow)-isoform of MHC in the adult mouse heart causes dominant-negative functional effects
JC Tardiff et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2000)
Intracoronary adenovirus-mediated delivery and overexpression of the β2-adrenergic receptor in the heart -: Prospects for molecular ventricular assistance
AS Shah et al.
CIRCULATION (2000)
Formation of sarcoglycan complex with differentiation in cultured myocytes
S Noguchi et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)
Disruption of heart sarcoglycan complex and severe cardiomyopathy caused by β sarcoglycan mutations
R Barresi et al.
JOURNAL OF MEDICAL GENETICS (2000)
Rescue of skeletal muscles of γ-sarcoglycan-deficient mice with adeno-associated virus-mediated gene transfer
L Cordier et al.
MOLECULAR THERAPY (2000)
Transgenic mouse model of stunned myocardium
AM Murphy et al.
SCIENCE (2000)
Inhibition of the c-Jun N-terminal kinase/AP-1 and NF-κB pathways by PICOT, a novel protein kinase C-interacting protein with a thioredoxin homology domain
S Witte et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure
MI Miyamoto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Differential expression of cardiac titin isoforms and modulation of cellular stiffness
O Cazorla et al.
CIRCULATION RESEARCH (2000)
Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector
MA Kay et al.
NATURE GENETICS (2000)
Activation of the small GTP-binding protein Ras in the heart by hypertrophic agonists
PH Sugden et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2000)
Remodeling the cardiac sarcomere using transgenesis
J Robbins
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